Platelet secretion and hemostasis require syntaxin-binding protein STXBP5

Genome-Wide Association Study for Circulating Tissue Plasminogen Activator Levels and Functional Follow-Up Implicates Endothelial STXBP5 and STX2

(2014) Jie Huang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Syntaxin-binding protein STXBP5 inhibits endothelial exocytosis and promotes platelet secretion

(2014) Qiuyu Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Harnessing the Platelet Signaling Network to Produce an Optimal Hemostatic Response

(2013) Lawrence F. Brass et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Munc18b/STXBP2 is required for platelet secretion

(2012) R. Al Hawas et al.   BLOOD

Syntaxin-11, but not syntaxin-2 or syntaxin-4, is required for platelet secretion

(2012) S. Ye et al.   BLOOD

Granule exocytosis is required for platelet spreading: differential sorting of  -granules expressing VAMP-7

(2012) C. G. Peters et al.   BLOOD

Synaptotagmin-like protein 4 and Rab8 interact and increase dense granule release in platelets

(2012) A. HAMPSON et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Effect of Genetic Variation in STXBP5 and STX2 on von Willebrand Factor and Bleeding Phenotype in Type 1 von Willebrand Disease Patients

(2012) Janine E. van Loon et al.   PLoS One

Genetic determinants of plasma von Willebrand factor antigen levels: a target gene SNP and haplotype analysis of ARIC cohort

(2011) M. Campos et al.   BLOOD

Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes

(2011) J. W. Rowley et al.   BLOOD

Biphasic roles for soluble guanylyl cyclase (sGC) in platelet activation

(2011) G. Zhang et al.   BLOOD

Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels

(2011) Guillemette Antoni et al.   BMC Medical Genetics

Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics

(2011) Julia Maria Burkhart et al.   Journal of Proteomics

Antiplatelet agents in cardiovascular disease

(2011) Renato D. Lopes   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Tomosyn-dependent regulation of synaptic transmission is required for a late phase of associative odor memory

(2011) K. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic Vesicle Exocytosis

(2011) T. C. Sudhof et al.   Cold Spring Harbor Perspectives in Biology

Platelet secretion defect in patients with familial hemophagocytic lymphohistiocytosis type 5 (FHL-5)

(2010) K. Sandrock et al.   BLOOD

Genetic variation associated with plasma von Willebrand factor levels and the risk of incident venous thrombosis

(2010) N. L. Smith et al.   BLOOD

A revised model for the secretion of tPA and cytokines from cultured endothelial cells

(2010) L. Knipe et al.   BLOOD

Novel Associations of Multiple Genetic Loci With Plasma Levels of Factor VII, Factor VIII, and von Willebrand Factor

(2010) Nicholas L. Smith et al.   CIRCULATION

Effect of Genetic Variations in Syntaxin-Binding Protein-5 and Syntaxin-2 on von Willebrand Factor Concentration and Cardiovascular Risk

(2010) Janine E. van Loon et al.   Circulation-Cardiovascular Genetics

Antiplatelet therapies for the treatment of cardiovascular disease

(2010) Alan D. Michelson   NATURE REVIEWS DRUG DISCOVERY

Endobrevin/VAMP-8-dependent dense granule release mediates thrombus formation in vivo

(2009) G. J. Graham et al.   BLOOD

Novel copy number variants in children with autism and additional developmental anomalies

(2009) L. K. Davis et al.   Journal of Neurodevelopmental Disorders

Novel molecules in calcium signaling in platelets

(2009) W. BERGMEIER et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Friends and foes in synaptic transmission: the role of tomosyn in vesicle priming

(2009) Uri Ashery et al.   TRENDS IN NEUROSCIENCES

Dual inhibition of SNARE complex formation by tomosyn ensures controlled neurotransmitter release

(2008) Toshiaki Sakisaka et al.   JOURNAL OF CELL BIOLOGY