A prospective view of animal and human Fasciolosis

Fasciola hepaticategumental antigens induce anergic-like T cells via dendritic cells in a mannose receptor-dependent manner

(2016) Allison Aldridge et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Higher physiopathogenicity byFasciola giganticathan by the genetically closeF. hepatica: experimental long-term follow-up of biochemical markers

(2016) M. Adela Valero et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Treatment Failure after Multiple Courses of Triclabendazole among Patients with Fascioliasis in Cusco, Peru: A Case Series

(2016) Miguel M. Cabada et al.   PLoS Neglected Tropical Diseases

Tegument Glycoproteins and Cathepsins of Newly Excysted Juvenile Fasciola hepatica Carry Mannosidic and Paucimannosidic N-glycans

(2016) Andres Garcia-Campos et al.   PLoS Neglected Tropical Diseases

The Intestinal Microbiota Contributes to the Ability of Helminths to Modulate Allergic Inflammation

(2015) Mario M. Zaiss et al.   IMMUNITY

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

(2015) Jia Sun et al.   IMMUNITY

Characterisation of a novel panel of polymorphic microsatellite loci for the liver fluke, Fasciola hepatica, using a next generation sequencing approach

(2015) Krystyna Cwiklinski et al.   INFECTION GENETICS AND EVOLUTION

Applying spatiotemporal models to study risk of smear-positive tuberculosis in Iran, 2001–2012

(2015) T. Jafari-Koshki et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

The Extracellular Vesicles of the Helminth Pathogen,Fasciola hepatica: Biogenesis Pathways and Cargo Molecules Involved in Parasite Pathogenesis

(2015) Krystyna Cwiklinski et al.   MOLECULAR & CELLULAR PROTEOMICS

Transcriptional analysis identifies key genes involved in metabolism, fibrosis/tissue repair and the immune response against Fasciola hepatica in sheep liver

(2015) Cristian A Alvarez Rojas et al.   Parasites & Vectors

Fasciola hepatica from naturally infected sheep and cattle in Great Britain are diploid

(2015) N. J. BEESLEY et al.   PARASITOLOGY

The gut microbiome in the helminth infected host

(2015) Francisca Mutapi   TRENDS IN PARASITOLOGY

Fasciola hepatica vaccine: We may not be there yet but we’re on the right road

(2015) Verónica Molina-Hernández et al.   VETERINARY PARASITOLOGY

The Interplay of the Gut Microbiome, Bile Acids, and Volatile Organic Compounds

(2015) Nidhi M. Sagar et al.   Gastroenterology Research and Practice

Differences in the Faecal Microbiome in Schistosoma haematobium Infected Children vs. Uninfected Children

(2015) Gemma Louise Kay et al.   PLoS Neglected Tropical Diseases

Hybridization in Parasites: Consequences for Adaptive Evolution, Pathogenesis, and Public Health in a Changing World

(2015) Kayla C. King et al.   PLoS Pathogens

The Fasciola hepatica genome: gene duplication and polymorphism reveals adaptation to the host environment and the capacity for rapid evolution

(2015) Krystyna Cwiklinski et al.   GENOME BIOLOGY

Chronic Trichuris muris Infection in C57BL/6 Mice Causes Significant Changes in Host Microbiota and Metabolome: Effects Reversed by Pathogen Clearance

(2015) Ashley Houlden et al.   PLoS One

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

The cross talk between microbiota and the immune system: metabolites take center stage

(2014) Hagit Shapiro et al.   CURRENT OPINION IN IMMUNOLOGY

Liver fluke vaccines in ruminants: strategies, progress and future opportunities

(2014) Hayley Toet et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Hybridization, Introgression, and the Nature of Species Boundaries

(2014) Richard G. Harrison et al.   JOURNAL OF HEREDITY

Helminth Infections Decrease Host Susceptibility to Immune-Mediated Diseases

(2014) Joel V. Weinstock et al.   JOURNAL OF IMMUNOLOGY

The revolution of whole genome sequencing to study parasites

(2014) Sarah Jayne Forrester et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Gaining biological perspectives from schistosome genomes

(2014) Geoffrey N. Gobert et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Life at the beginning: perturbation of the microbiota by antibiotics in early life and its role in health and disease

(2014) Sebastian Zeissig et al.   NATURE IMMUNOLOGY

Helminth.net: expansions to Nematode.net and an introduction to Trematode.net

(2014) John Martin et al.   NUCLEIC ACIDS RESEARCH

Generating a detailed protein profile ofFasciola hepaticaduring the chronic stage of infection in cattle

(2014) Orçun Haçarız et al.   PROTEOMICS

The gut microbiome, probiotics, bile acids axis, and human health

(2014) Mitchell Lawrence Jones et al.   TRENDS IN MICROBIOLOGY

The Opisthorchis viverrini genome provides insights into life in the bile duct

(2014) Neil D. Young et al.   Nature Communications

Comparative Assessment of ELISAs Using Recombinant Saposin-Like Protein 2 and recombinant Cathepsin L-1 from Fasciola hepatica for the Serodiagnosis of Human Fasciolosis

(2014) Bruno Gottstein et al.   PLoS Neglected Tropical Diseases

Helminth Colonization Is Associated with Increased Diversity of the Gut Microbiota

(2014) Soo Ching Lee et al.   PLoS Neglected Tropical Diseases

Repurposing drugs for the treatment and control of helminth infections

(2014) Gordana Panic et al.   International Journal for Parasitology-Drugs and Drug Resistance

Immunodetection of Fasciola gigantica Circulating Antigen in Sera of Infected Individuals for Laboratory Diagnosis of Human Fascioliasis

(2013) Abdelfattah M. Attallah et al.   Clinical and Vaccine Immunology

Fasciola hepatica Tegumental Coat Impairs Mast Cells' Ability To Drive Th1 Immune Responses

(2013) K. V. Vukman et al.   JOURNAL OF IMMUNOLOGY

Adult somatic stem cells in the human parasite Schistosoma mansoni

(2013) James J. Collins III et al.   NATURE

Effect of helminth-induced immunity on infections with microbial pathogens

(2013) Padmini Salgame et al.   NATURE IMMUNOLOGY

Commensal bacteria at the interface of host metabolism and the immune system

(2013) Jonathan R Brestoff et al.   NATURE IMMUNOLOGY

Fasciola hepaticategumental coat antigen suppresses MAPK signalling in dendritic cells and up-regulates the expression of SOCS3

(2013) K. V. Vukman et al.   PARASITE IMMUNOLOGY

Identification of putative markers of triclabendazole resistance by a genome-wide analysis of genetically recombinant Fasciola hepatica

(2013) J. HODGKINSON et al.   PARASITOLOGY

Th1 and Th2 cytokine gene expression in primary infection and vaccination against Fasciola gigantica in buffaloes by real-time PCR

(2013) Niranjan Kumar et al.   PARASITOLOGY RESEARCH

The Carcinogenic Liver Fluke, Clonorchis sinensis: New Assembly, Reannotation and Analysis of the Genome and Characterization of Tissue Transcriptomes

(2013) Yan Huang et al.   PLoS One

Patent Human Infections with the Whipworm, Trichuris trichiura, Are Not Associated with Alterations in the Faecal Microbiota

(2013) Philip Cooper et al.   PLoS One

The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic Treg Cell Homeostasis

(2013) P. M. Smith et al.   SCIENCE

Peripheral blood lymphocyte subsets in Fasciola hepatica infected and immunised goats

(2013) R. Zafra et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Immunomodulatory molecules of Fasciola hepatica: Candidates for both vaccine and immunotherapeutic development

(2013) John P. Dalton et al.   VETERINARY PARASITOLOGY

The Diagnosis of Human Fascioliasis by Enzyme-Linked Immunosorbent Assay (ELISA) Using Recombinant Cathepsin L Protease

(2013) Bibiana Gonzales Santana et al.   PLoS Neglected Tropical Diseases

Functional genomic characterization of neoblast-like stem cells in larval Schistosoma mansoni

(2013) Bo Wang et al.   eLife

Butyrate increases IL-23 production by stimulated dendritic cells

(2012) Bradford E. Berndt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Helminth-host immunological interactions: prevention and control of immune-mediated diseases

(2012) David E. Elliott et al.   Annals of the New York Academy of Sciences

The Microbiome in Infectious Disease and Inflammation

(2012) Kenya Honda et al.   Annual Review of Immunology

Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells

(2012) Lu Liu et al.   CELLULAR IMMUNOLOGY

Trematode Infections

(2012) Thomas Fürst et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Early and Late Peritoneal and Hepatic Changes in Goats Immunized with Recombinant Cathepsin L1 and Infected with Fasciola hepatica

(2012) R. Zafra et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Proteomics and in Silico Approaches To Extend Understanding of the Glutathione Transferase Superfamily of the Tropical Liver Fluke Fasciola gigantica

(2012) Russell M. Morphew et al.   JOURNAL OF PROTEOME RESEARCH

Worm Burden-Dependent Disruption of the Porcine Colon Microbiota by Trichuris suis Infection

(2012) Sitao Wu et al.   PLoS One

Extracellular Vesicles from Parasitic Helminths Contain Specific Excretory/Secretory Proteins and Are Internalized in Intestinal Host Cells

(2012) Antonio Marcilla et al.   PLoS One

Early hepatic and peritoneal changes and immune response in goats vaccinated with a recombinant glutathione transferase sigma class and challenged with Fasciola hepatica

(2012) R. Zafra et al.   RESEARCH IN VETERINARY SCIENCE

Interactions Between the Microbiota and the Immune System

(2012) L. V. Hooper et al.   SCIENCE

Hyperendemic human fascioliasis in Andean valleys: An altitudinal transect analysis in children of Cajamarca province, Peru

(2011) L. Carolina González et al.   ACTA TROPICA

Dysregulation of Allergic Airway Inflammation in the Absence of Microbial Colonization

(2011) Tina Herbst et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Role of the Commensal Microbiota in Normal and Pathogenic Host Immune Responses

(2011) Dan R. Littman et al.   Cell Host & Microbe

Macrophage activation governs schistosomiasis-induced inflammation and fibrosis

(2011) Luke Barron et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The effects of commensal microbiota on immune cell subsets and inflammatory responses

(2011) Takatoshi Chinen et al.   IMMUNOLOGICAL REVIEWS

Molecular and immunological characterization of Fasciola antigens recognized by the MM3 monoclonal antibody

(2011) L. Muiño et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Resistance to liver fluke infection in the natural sheep host is correlated with a type-1 cytokine response

(2011) J. PLEASANCE et al.   PARASITE IMMUNOLOGY

Evaluation of a 14.5 kDa-Fasciola gigantica fatty acid binding protein as a diagnostic antigen for human fascioliasis

(2011) Gamal Allam et al.   PARASITOLOGY RESEARCH

Intestinal microbiota: Shaping local and systemic immune responses

(2011) Michael J. Molloy et al.   SEMINARS IN IMMUNOLOGY

Reducing the future threat from (liver) fluke: realistic prospect or quixotic fantasy?

(2011) Ian Fairweather   VETERINARY PARASITOLOGY

Innate and adaptive resistance of Indonesian Thin Tail sheep to liver fluke: A comparative analysis of Fasciola gigantica and Fasciola hepatica infection

(2011) Jill Pleasance et al.   VETERINARY PARASITOLOGY

A Portrait of the Transcriptome of the Neglected Trematode, Fasciola gigantica—Biological and Biotechnological Implications

(2011) Neil D. Young et al.   PLoS Neglected Tropical Diseases

Development and Evaluation of a New Lateral Flow Immunoassay for Serodiagnosis of Human Fasciolosis

(2011) Victoria Martínez-Sernández et al.   PLoS Neglected Tropical Diseases

Intestinal Bacteria and the Regulation of Immune Cell Homeostasis

(2010) David A. Hill et al.   Annual Review of Immunology

Helminths and dendritic cells: Sensing and regulating via pattern recognition receptors, Th2 and Treg responses

(2010) Bart Everts et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Regulatory T cells in human geohelminth infection suppress immune responses to BCG andPlasmodium falciparum

(2010) Linda J. Wammes et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Gut-Residing Segmented Filamentous Bacteria Drive Autoimmune Arthritis via T Helper 17 Cells

(2010) Hsin-Jung Wu et al.   IMMUNITY

Alteration of the murine gut microbiota during infection with the parasitic helminth Heligmosomoides polygyrus

(2010) Seth T. Walk et al.   INFLAMMATORY BOWEL DISEASES

Similarity and Diversity in Macrophage Activation by Nematodes, Trematodes, and Cestodes

(2010) Stephen J. Jenkins et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Interleukin-2 and interleukin-10 gene expression in calves experimentally infected with Fasciola gigantica

(2010) S.L. Ingale et al.   Livestock Science

FLOTAC: new multivalent techniques for qualitative and quantitative copromicroscopic diagnosis of parasites in animals and humans

(2010) Giuseppe Cringoli et al.   Nature Protocols

Worm secretory molecules are causing alarm

(2010) Mark W. Robinson et al.   TRENDS IN PARASITOLOGY

Evaluation of hepatic changes and local and systemic immune responses in goats immunized with recombinant Peroxiredoxin (Prx) and challenged with Fasciola hepatica

(2010) Ricardo E. Mendes et al.   VACCINE

A preliminary study to understand the effect of Fasciola hepatica tegument on naïve macrophages and humoral responses in an ovine model

(2010) O. Haçarız et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Climate change and infectious disease: helminthological challenges to farmed ruminants in temperate regions

(2009) J. van Dijk et al.   Animal

Food-Borne Trematodiases

(2009) J. Keiser et al.   CLINICAL MICROBIOLOGY REVIEWS

Major Secretory Antigens of the Helminth Fasciola hepatica Activate a Suppressive Dendritic Cell Phenotype That Attenuates Th17 Cells but Fails To Activate Th2 Immune Responses

(2009) D. J. Dowling et al.   INFECTION AND IMMUNITY

Mechanisms of mast cell signaling in anaphylaxis

(2009) Dean D. Metcalfe et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions

(2009) Matteo Fumagalli et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Bile Acid Receptor FXR Is a Modulator of Intestinal Innate Immunity

(2009) P. Vavassori et al.   JOURNAL OF IMMUNOLOGY

Infection with a Helminth Parasite Attenuates Autoimmunity through TGF- -Mediated Suppression of Th17 and Th1 Responses

(2009) K. P. Walsh et al.   JOURNAL OF IMMUNOLOGY

An Integrated Transcriptomics and Proteomics Analysis of the Secretome of the Helminth PathogenFasciola hepatica

(2009) Mark W. Robinson et al.   MOLECULAR & CELLULAR PROTEOMICS

IL-10 and TGF-β1 are associated with variations in fluke burdens following experimental fasciolosis in sheep

(2009) O. HAÇARIZ et al.   PARASITE IMMUNOLOGY

Immunity-mediated regulation of fecundity in the nematode Heligmosomoides polygyrus – the potential role of mast cells

(2009) K. HASHIMOTO et al.   PARASITOLOGY

Molecular characterization of Fasciola hepatica, Fasciola gigantica, and aspermic Fasciola sp. in China based on nuclear and mitochondrial DNA

(2009) Mao Peng et al.   PARASITOLOGY RESEARCH

Zoonotic helminth infections with particular emphasis on fasciolosis and other trematodiases

(2009) M. W. Robinson et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Climate change effects on trematodiases, with emphasis on zoonotic fascioliasis and schistosomiasis

(2009) Santiago Mas-Coma et al.   VETERINARY PARASITOLOGY

Short-chain fatty acids act as antiinflammatory mediatorsby regulating prostaglandin E2 and cytokines

(2009) Mary Ann Cox et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Expression and function of the bile acid receptor TGR5 in Kupffer cells

(2008) Verena Keitel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Diet-Induced Obesity Is Linked to Marked but Reversible Alterations in the Mouse Distal Gut Microbiome

(2008) Peter J. Turnbaugh et al.   Cell Host & Microbe

Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages

(2008) Sheila Donnelly et al.   FASEB JOURNAL

Review series on helminths, immune modulation and the hygiene hypothesis: Immunity against helminths and immunological phenomena in modern human populations: coevolutionary legacies?

(2008) Joseph A. Jackson et al.   IMMUNOLOGY

Helminth infections: the great neglected tropical diseases

(2008) Peter J. Hotez et al.   JOURNAL OF CLINICAL INVESTIGATION

Occurrence of spermic diploid and aspermic triploid forms of Fasciola in Vietnam and their molecular characterization based on nuclear and mitochondrial DNA

(2008) Tadashi Itagaki et al.   PARASITOLOGY INTERNATIONAL

The effect of Quil A adjuvant on the course of experimental Fasciola hepatica infection in sheep

(2008) O. Haçarız et al.   VACCINE

Human fascioliasis and the presence of hybrid/introgressed forms of Fasciola hepatica and Fasciola gigantica in Vietnam

(2007) Thanh Hoa Le et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Interferon-gamma and interleukin-4 expression during Fasciola gigantica primary infection in crossbred bovine calves as determined by real -time PCR

(2007) S.L. Ingale et al.   VETERINARY PARASITOLOGY