Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases
Published 2016 View Full Article
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Title
Integrated Approaches to Drug Discovery for Oxidative Stress-Related Retinal Diseases
Authors
Keywords
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Journal
Oxidative Medicine and Cellular Longevity
Volume 2016, Issue -, Pages 1-9
Publisher
Hindawi Limited
Online
2016-12-08
DOI
10.1155/2016/2370252
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Note: Only part of the references are listed.- Systems Pharmacology Links GPCRs with Retinal Degenerative Disorders
- (2016) Yu Chen et al. Annual Review of Pharmacology and Toxicology
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- (2016) Gabriela de Moraes et al. CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
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- Using zebrafish in systems toxicology for developmental toxicity testing
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- Fenofibrate and Diabetic Retinopathy
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- (2016) R Richardson et al. EYE
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- (2016) Yuichi Saito et al. JOURNAL OF PHARMACOLOGICAL SCIENCES
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- Genome-wide association analysis identifies TXNRD2, ATXN2 and FOXC1 as susceptibility loci for primary open-angle glaucoma
- (2016) Jessica N Cooke Bailey et al. NATURE GENETICS
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- (2016) Chiea Chuen Khor et al. NATURE GENETICS
- The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults
- (2016) Małgorzata Nita et al. Oxidative Medicine and Cellular Longevity
- Drug discovery in ophthalmology: past success, present challenges, and future opportunities
- (2016) Nicholas J. D. Gower et al. BMC Ophthalmology
- Neuoroprotective efficacies by KUS121, a VCP modulator, on animal models of retinal degeneration
- (2016) Tomoko Hasegawa et al. Scientific Reports
- Using zebrafish in systems toxicology for developmental toxicity testing
- (2016) Yuhei Nishimura et al. CONGENITAL ANOMALIES
- Neuroprotection as a Therapeutic Target for Diabetic Retinopathy
- (2016) Cristina Hernández et al. Journal of Diabetes Research
- Downregulation of GSTK1 Is a Common Mechanism Underlying Hypertrophic Cardiomyopathy
- (2016) Shota Sasagawa et al. Frontiers in Pharmacology
- EP300 Protects from Light-Induced Retinopathy in Zebrafish
- (2016) Reiko Kawase et al. Frontiers in Pharmacology
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- (2015) Renu A. Kowluru et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Zebrafish as a systems toxicology model for developmental neurotoxicity testing
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- An Experimental Model for Exudative Age-related Macular Degeneration with Choroidal Neovascularization Using the Common Marmoset
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- BDNF impairment is associated with age-related changes in the inner retina and exacerbates experimental glaucoma
- (2014) Vivek Gupta et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Zebrafish—on the move towards ophthalmological research
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- (2013) Robert M. Plenge et al. NATURE REVIEWS DRUG DISCOVERY
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- (2013) Vivian Law et al. NUCLEIC ACIDS RESEARCH
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- (2012) Vicki Chrysostomou et al. CURRENT OPINION IN PHARMACOLOGY
- Architecture of the human regulatory network derived from ENCODE data
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- (2012) Kang Zhang et al. NATURE REVIEWS DRUG DISCOVERY
- Mechanisms of Age-Related Macular Degeneration
- (2012) Jayakrishna Ambati et al. NEURON
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- (2012) Jennifer L. Wilkinson-Berka et al. PEPTIDES
- An Alteration in the Lateral Geniculate Nucleus of Experimental Glaucoma Monkeys: In vivo Positron Emission Tomography Imaging of Glial Activation
- (2012) Masamitsu Shimazawa et al. PLoS One
- The Role of Mislocalized Phototransduction in Photoreceptor Cell Death of Retinitis Pigmentosa
- (2012) Takeshi Nakao et al. PLoS One
- Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia
- (2012) Yukiya Suzuki et al. Scientific Reports
- Interactome Networks and Human Disease
- (2011) Marc Vidal et al. CELL
- Probucol ameliorates renal and metabolic sequelae of primary CoQ deficiency inPdss2mutant mice
- (2011) Marni J. Falk et al. EMBO Molecular Medicine
- Retinal remodeling in the Tg P347L rabbit, a large-eye model of retinal degeneration
- (2011) Bryan William Jones et al. JOURNAL OF COMPARATIVE NEUROLOGY
- miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes
- (2011) X.-Y. Bai et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Self-organizing optic-cup morphogenesis in three-dimensional culture
- (2011) Mototsugu Eiraku et al. NATURE
- Nanoceria Inhibit the Development and Promote the Regression of Pathologic Retinal Neovascularization in the Vldlr Knockout Mouse
- (2011) Xiaohong Zhou et al. PLoS One
- Multi-way association extraction and visualization from biological text documents using hyper-graphs: Applications to genetic association studies for diseases
- (2010) Snehasis Mukhopadhyay et al. ARTIFICIAL INTELLIGENCE IN MEDICINE
- SUN N8075, a novel radical scavenger, protects against retinal cell death in mice
- (2010) Mai Akane et al. NEUROSCIENCE LETTERS
- CD36 ligands promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer
- (2009) Cameron R Stewart et al. NATURE IMMUNOLOGY
- The role of vascular endothelial growth factor and other endogenous interplayers in age-related macular degeneration
- (2008) Salvatore Grisanti et al. PROGRESS IN RETINAL AND EYE RESEARCH
- Peroxisome Proliferator-Activated Receptor and Age-Related Macular Degeneration
- (2008) Alexandra A. Herzlich et al. PPAR Research
- PPAR-αLigands as Potential Therapeutic Agents for Wet Age-Related Macular Degeneration
- (2008) Marisol del V Cano et al. PPAR Research
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