Pharmacological inhibition of TLR4-NOX4 signal protects against neuronal death in transient focal ischemia

Disruption of downstream MyD88 or TRIF Toll-like receptor signaling does not protect against cerebral ischemia

(2011) Bolanle M. Famakin et al.   BRAIN RESEARCH

Acute inhibition of TAK1 protects against neuronal death in cerebral ischemia

(2011) M Neubert et al.   CELL DEATH AND DIFFERENTIATION

Toll-like receptors 2 and 4 in ischemic stroke: Outcome and therapeutic values

(2011) David Brea et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TLR2 Ligand Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of Phosphoinositide 3-Kinase/Akt Signaling

(2011) C. Lu et al.   JOURNAL OF IMMUNOLOGY

Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury

(2010) S Ben Mkaddem et al.   CELL DEATH AND DIFFERENTIATION

HMBG1 Mediates Ischemia—Reperfusion Injury by TRIF-Adaptor Independent Toll-Like Receptor 4 Signaling

(2010) Qing-Wu Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Blocking TLR2 in vivo Protects against Accumulation of Inflammatory Cells and Neuronal Injury in Experimental Stroke

(2010) Gina Ziegler et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Toll-like receptor 4 (TLR4), but not TLR3 or TLR9, knock-out mice have neuroprotective effects against focal cerebral ischemia

(2010) K. Hyakkoku et al.   NEUROSCIENCE

Post-treatment of a BiP inducer prevents cell death after middle cerebral artery occlusion in mice

(2010) Yasuhisa Oida et al.   NEUROSCIENCE LETTERS

High-Mobility Group Box 1 Promotes Metalloproteinase-9 Upregulation Through Toll-Like Receptor 4 After Cerebral Ischemia

(2010) Jianhua Qiu et al.   STROKE

Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

(2010) Christoph Kleinschnitz et al.   PLOS BIOLOGY

The TRIF-dependent signaling pathway is not required for acute cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BRAIN RESEARCH

Analysis of binding site for the novel small-molecule TLR4 signal transduction inhibitor TAK-242 and its therapeutic effect on mouse sepsis model

(2009) K Takashima et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

TLR4-mediated MyD88-dependent signaling pathway is activated by cerebral ischemia–reperfusion in cortex in mice

(2008) Yin Gao et al.   BIOMEDICINE & PHARMACOTHERAPY

Upregulated Expression of Toll-Like Receptor 4 in Monocytes Correlates with Severity of Acute Cerebral Infarction

(2008) Qing-wu Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Toll-Like Receptor 4 Is Involved in Subacute Stress–Induced Neuroinflammation and in the Worsening of Experimental Stroke

(2008) Javier R. Caso et al.   STROKE