Mechanistic studies on intramolecular C–H trifluoromethoxylation of (hetero)arenes via OCF3-migration

Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas

(2016) Yu Zhou et al.   CHEMICAL REVIEWS

Access to a new class of synthetic building blocks via trifluoromethoxylation of pyridines and pyrimidines

(2016) Pengju Feng et al.   Chemical Science

Silver-Mediated Oxidative Trifluoromethylation of Phenols: Direct Synthesis of Aryl Trifluoromethyl Ethers

(2015) Jian-Bo Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Sonidegib: First Global Approval

(2015) Celeste B. Burness   DRUGS

Trifluoromethoxylation of Arenes: Synthesis ofortho-Trifluoromethoxylated Aniline Derivatives by OCF3Migration

(2014) Katarzyna N. Hojczyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Rearrangement of N-Oxyenamines and Related Reactions

(2014) Andrey A. Tabolin et al.   CHEMICAL REVIEWS

A Unique Solution-Processable n-Type Semiconductor Material Design for High-Performance Organic Field-Effect Transistors

(2014) Masashi Mamada et al.   CHEMISTRY OF MATERIALS

Fluorinated Compounds in Medicinal Chemistry: Recent Applications, Synthetic Advances and Matched-Pair Analyses

(2014) David Barnes-Seeman et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Trifluoromethyl Ethers and –Thioethers as Tools for Medicinal Chemistry and Drug Discovery

(2014) Gregory Landelle et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

O-Trifluoromethylation ofN,N-Disubstituted Hydroxylamines with Hypervalent Iodine Reagents

(2014) Václav Matoušek et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Tandem Trifluoromethylation/Semipinacol Rearrangement of Allylic Alcohols

(2013) Zhi-Min Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylation-Initiated Radical 1,2-Aryl Migration in α,α-Diaryl Allylic Alcohols

(2013) Xiaowu Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Introduction of Fluorine and Fluorine-Containing Functional Groups

(2013) Theresa Liang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Redox chemistry of trifluoromethyl sulfonium salts as CF3 radical sources

(2013) Satoshi Mizuta et al.   JOURNAL OF FLUORINE CHEMISTRY

Trifluoromethylation of Allylsilanes under Photoredox Catalysis

(2013) Satoshi Mizuta et al.   ORGANIC LETTERS

Transition-Metal-Free Trifluoromethylaminoxylation of Alkenes

(2012) Yi Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Baseline sensitivity and efficacy of thifluzamide inRhizoctonia solani

(2012) Y. Chen et al.   ANNALS OF APPLIED BIOLOGY

Direct trifluoro-methoxylation of aromatics with perfluoro-methyl-hypofluorite

(2012) Francesco Venturini et al.   JOURNAL OF FLUORINE CHEMISTRY

NMS-P937, an Orally Available, Specific Small-Molecule Polo-like Kinase 1 Inhibitor with Antitumor Activity in Solid and Hematologic Malignancies

(2012) B. Valsasina et al.   MOLECULAR CANCER THERAPEUTICS

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

(2011) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NMS-P937, a 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivative as potent and selective Polo-like kinase 1 inhibitor

(2011) Italo Beria et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

(2011) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethoxylation of Aryl Stannanes and Arylboronic Acids

(2011) Chenghong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

4,5-Dihydro-1H-pyrazolo[4,3-h]quinazolines as potent and selective Polo-like kinase 1 (PLK1) inhibitors

(2010) Italo Beria et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

A General Approach to (Trifluoromethoxy)pyridines: First X-ray Structure Determinations and Quantum Chemistry Studies

(2010) Baptiste Manteau et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Trifluoromethyl ethers – synthesis and properties of an unusual substituent

(2008) Frédéric R Leroux et al.   Beilstein Journal of Organic Chemistry

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Reactivity of a 10-I-3 Hypervalent Iodine Trifluoromethylation Reagent With Phenols

(2008) Kyrill Stanek et al.   JOURNAL OF ORGANIC CHEMISTRY

Anion-π interactions

(2007) Brandi L. Schottel et al.   CHEMICAL SOCIETY REVIEWS

Understanding organofluorine chemistry. An introduction to the C–F bond

(2007) David O'Hagan   CHEMICAL SOCIETY REVIEWS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

Versatile application of trifluoromethyl triflate

(2007) Alexander A. Kolomeitsev et al.   TETRAHEDRON LETTERS