The autoimmunity-oral microbiome connection

Systemic lupus erythematosus: still a challenge for physicians

(2016) A. A. Bengtsson et al.   JOURNAL OF INTERNAL MEDICINE

The microbiome-systemic diseases connection

(2016) TA van der Meulen et al.   ORAL DISEASES

A practical guide to the oral microbiome and its relation to health and disease

(2016) K Krishnan et al.   ORAL DISEASES

Infection and Lupus: Which Causes Which?

(2016) Sarah Doaty et al.   Current Rheumatology Reports

The Autoimmune Ecology

(2016) Juan-Manuel Anaya et al.   Frontiers in Immunology

Altered Mucosal Microbiome Diversity and Disease Severity in Sjögren Syndrome

(2016) Cintia S. de Paiva et al.   Scientific Reports

AB0188 Systematic Analysis of the Oral Microbiome in Primary SjÖgren's Syndrome Suggest Enrichment of Distinct Microbes

(2015) P. Sandhya et al.   ANNALS OF THE RHEUMATIC DISEASES

Crystal structure ofPorphyromonas gingivalispeptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

(2015) Anna B Montgomery et al.   ANNALS OF THE RHEUMATIC DISEASES

Variation in the Human Immune System Is Largely Driven by Non-Heritable Influences

(2015) Petter Brodin et al.   CELL

Fueling the Fire with Fibers: Bacterial Amyloids Promote Inflammatory Disorders

(2015) Caitlin N. Spaulding et al.   Cell Host & Microbe

Immuno-ecology: how the microbiome regulates tolerance and autoimmunity

(2015) Alexandra Paun et al.   CURRENT OPINION IN IMMUNOLOGY

Microbial Nucleic Acid Sensing in Oral and Systemic Diseases

(2015) K.E. Crump et al.   JOURNAL OF DENTAL RESEARCH

The oral and gut microbiomes are perturbed in rheumatoid arthritis and partly normalized after treatment

(2015) Xuan Zhang et al.   NATURE MEDICINE

Immunopathogenesis of IBD: current state of the art

(2015) Heitor S. P. de Souza et al.   Nature Reviews Gastroenterology & Hepatology

TLR-7 and -9 Stimulation of Peripheral Blood B Cells Indicate Altered TLR Signalling in Primary Sjögren's Syndrome Patients by Increased Secretion of Cytokines

(2015) M. Karlsen et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Antibodies to early EBV, CMV, and HHV6 antigens in systemic lupus erythematosus patients

(2015) NS Rasmussen et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Local Joint Inflammation and Histone Citrullination in a Murine Model of the Transition From Preclinical Autoimmunity to Inflammatory Arthritis

(2015) Dong Hyun Sohn et al.   Arthritis & Rheumatology

Dynamics of Gut Microbiota in Autoimmune Lupus

(2014) Husen Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Anti-citrullinated peptides as autoantigens in rheumatoid arthritis—relevance to treatment

(2014) Lazaros I. Sakkas et al.   AUTOIMMUNITY REVIEWS

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

T cell epitope mimicry between Sjögren's syndrome Antigen A (SSA)/Ro60 and oral, gut, skin and vaginal bacteria

(2014) Agnieszka Szymula et al.   CLINICAL IMMUNOLOGY

Probiotics in the Mechanism of Protection Against Gut Inflammation and Therapy of Gastrointestinal Disorders

(2014) Katarzyna Dylag et al.   CURRENT PHARMACEUTICAL DESIGN

The microbial basis of inflammatory bowel diseases

(2014) Sushila R. Dalal et al.   JOURNAL OF CLINICAL INVESTIGATION

Periodontal Pathogens Directly Promote Autoimmune Experimental Arthritis by Inducing a TLR2- and IL-1-Driven Th17 Response

(2014) S. G. de Aquino et al.   JOURNAL OF IMMUNOLOGY

Epigenetics and the microbiome: developing areas in the understanding of the aetiology of lupus

(2014) CJ Edwards et al.   LUPUS

Sjögren’s syndrome patients presenting with hypergammaglobulinemia are relatively unresponsive to cevimeline treatment

(2014) Koichiro Komai et al.   Modern Rheumatology

The gut microbiota and inflammatory bowel disease

(2014) Katsuyoshi Matsuoka et al.   Seminars in Immunopathology

Role ofHelicobacter pyloriinfection in autoimmune systemic rheumatic diseases

(2014) Mislav Radić   WORLD JOURNAL OF GASTROENTEROLOGY

Systematic review and meta-analysis of the sero-epidemiological association between Epstein-Barr virus and systemic lupus erythematosus

(2014) Peter Hanlon et al.   ARTHRITIS RESEARCH & THERAPY

Intestinal Dysbiosis Associated with Systemic Lupus Erythematosus

(2014) A. Hevia et al.   mBio

Implication of Epstein-Barr Virus Infection in Disease-Specific Autoreactive B Cell Activation in Ectopic Lymphoid Structures of Sjögren's Syndrome

(2014) Cristina Croia et al.   Arthritis & Rheumatology

Porphyromonas gingivalis peptidylarginine deiminase substrate specificity

(2013) Syatirah-Najmi Abdullah et al.   ANAEROBE

Genetic association and functional role of Crohn disease risk alleles involved in microbial sensing, autophagy, and endoplasmic reticulum (ER) stress

(2013) Eveline Hoefkens et al.   Autophagy

Influence of bacteria on epigenetic gene control

(2013) Kyoko Takahashi   CELLULAR AND MOLECULAR LIFE SCIENCES

Microbiome and mucosal inflammation as extra-articular triggers for rheumatoid arthritis and autoimmunity

(2013) Samuel B. Brusca et al.   CURRENT OPINION IN RHEUMATOLOGY

Dry Eye as a Mucosal Autoimmune Disease

(2013) Michael E. Stern et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

The subgingival microbiome in health and periodontitis and its relationship with community biomass and inflammation

(2013) Loreto Abusleme et al.   ISME Journal

Detection of oral bacterial DNA in synovial fluid

(2013) Stefan Reichert et al.   JOURNAL OF CLINICAL PERIODONTOLOGY

Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis

(2013) Xinyun Qiu et al.   Journal of Crohns & Colitis

Microbial Geography of the Oral Cavity

(2013) Á. Simón-Soro et al.   JOURNAL OF DENTAL RESEARCH

Recent progress on the role of gut microbiota in the pathogenesis of inflammatory bowel disease

(2013) Cheng Gong Yu et al.   Journal of Digestive Diseases

A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis

(2013) Stephen W. Scally et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Anti-citrullinated peptide autoantibodies, human leukocyte antigen shared epitope and risk of future rheumatoid arthritis: a nested case–control study

(2013) Elizabeth V Arkema et al.   ARTHRITIS RESEARCH & THERAPY

Porphyromonas gingivalis Facilitates the Development and Progression of Destructive Arthritis through Its Unique Bacterial Peptidylarginine Deiminase (PAD)

(2013) Katarzyna J. Maresz et al.   PLoS Pathogens

Expansion of intestinal Prevotella copri correlates with enhanced susceptibility to arthritis

(2013) Jose U Scher et al.   eLife

Epstein–Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis

(2012) Cristina Croia et al.   ANNALS OF THE RHEUMATIC DISEASES

Periodontal disease and the oral microbiota in new-onset rheumatoid arthritis

(2012) Jose U. Scher et al.   ARTHRITIS AND RHEUMATISM

Epstein-Barr Virus and Systemic Lupus Erythematosus

(2012) Anette Holck Draborg et al.   Clinical & Developmental Immunology

Lupus and Epstein-Barr

(2012) Judith A. James et al.   CURRENT OPINION IN RHEUMATOLOGY

Revisiting the old link between infection and autoimmune disease with commensals and T helper 17 cells

(2012) J. Magarian Blander et al.   IMMUNOLOGIC RESEARCH

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

Epigenetics: The link between nature and nurture

(2012) Stephanie A. Tammen et al.   MOLECULAR ASPECTS OF MEDICINE

A framework for human microbiome research

(2012)   NATURE

Structure, function and diversity of the healthy human microbiome

(2012)   NATURE

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

(2012) Soumya Raychaudhuri et al.   NATURE GENETICS

The gut microbiota in IBD

(2012) Chaysavanh Manichanh et al.   Nature Reviews Gastroenterology & Hepatology

Deep Sequencing of the Oral Microbiome Reveals Signatures of Periodontal Disease

(2012) Bo Liu et al.   PLoS One

Strategies for the Prevention of Postoperative Recurrence in Crohn's Disease: Results of a Decision Analysis

(2011) Ashwin N Ananthakrishnan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Antibiotic Therapy in Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis

(2011) Khurram J Khan et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Crohn disease: A current perspective on genetics, autophagy and immunity

(2011) Thaddeus S. Stappenbeck et al.   Autophagy

Binding with Nucleic Acids or Glycosaminoglycans Converts Soluble Protein Oligomers to Amyloid

(2011) Jeremy Di Domizio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

(2011) Van C. Willis et al.   JOURNAL OF IMMUNOLOGY

Anti-CCP antibodies: the past, the present and the future

(2011) Walther J. van Venrooij et al.   Nature Reviews Rheumatology

The oral microbiome in health and disease and the potential impact on personalized dental medicine

(2011) MF Zarco et al.   ORAL DISEASES

Tuberculosis as a risk factor for systemic lupus erythematosus: results of a nationwide study in Taiwan

(2011) Yu-Chao Lin et al.   RHEUMATOLOGY INTERNATIONAL

Commensal flora and the regulation of inflammatory and autoimmune responses

(2011) Jan Kranich et al.   SEMINARS IN IMMUNOLOGY

Immune complexes containing citrullinated fibrinogen costimulate macrophages via Toll-like receptor 4 and Fcγ receptor

(2010) Jeremy Sokolove et al.   ARTHRITIS AND RHEUMATISM

Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: Implications for autoimmunity in rheumatoid arthritis

(2010) Natalia Wegner et al.   ARTHRITIS AND RHEUMATISM

Subgingival Microbial Profiles of Smokers with Periodontitis

(2010) A.Y. Shchipkova et al.   JOURNAL OF DENTAL RESEARCH

DNA fromPorphyromonas gingivalisandTannerella forsythiainduce cytokine production in human monocytic cell lines

(2010) S.E. Sahingur et al.   Molecular Oral Microbiology

Expression of peptidylarginine deiminase from Porphyromonas gingivalis in Escherichia coli: Enzyme purification and characterization

(2009) Sofía B. Rodríguez et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Alterations of the synovial T cell repertoire in anti-citrullinated protein antibody-positive rheumatoid arthritis

(2009) Tineke Cantaert et al.   ARTHRITIS AND RHEUMATISM

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

(2009) L. A. Trouw et al.   ARTHRITIS AND RHEUMATISM

Antibodies to several citrullinated antigens are enriched in the joints of rheumatoid arthritis patients

(2009) Omri Snir et al.   ARTHRITIS AND RHEUMATISM

Autoimmune disease in the era of the metagenome

(2009) Amy D. Proal et al.   AUTOIMMUNITY REVIEWS

Defining the healthy "core microbiome" of oral microbial communities

(2009) Egija Zaura et al.   BMC MICROBIOLOGY

Induction of Intestinal Th17 Cells by Segmented Filamentous Bacteria

(2009) Ivaylo I. Ivanov et al.   CELL

The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress

(2009) Luke A. J. O'Neill   IMMUNOLOGICAL REVIEWS

Low counts of Faecalibacterium prausnitzii in colitis microbiota

(2009) H. Sokol et al.   INFLAMMATORY BOWEL DISEASES

Looking in the mouth for Crohnʼs disease

(2009) Marion Rowland et al.   INFLAMMATORY BOWEL DISEASES

A Crohn's disease–associated NOD2 mutation suppresses transcription of human IL10 by inhibiting activity of the nuclear ribonucleoprotein hnRNP-A1

(2009) Eiichiro Noguchi et al.   NATURE IMMUNOLOGY

Nod2 is required for the regulation of commensal microbiota in the intestine

(2009) T. Petnicki-Ocwieja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibodies to citrullinated α-enolase peptide 1 are specific for rheumatoid arthritis and cross-react with bacterial enolase

(2008) Karin Lundberg et al.   ARTHRITIS AND RHEUMATISM

Anti-cyclic citrullinated peptide-2 (CCP2) autoantibodies and extra-articular manifestations in Greek patients with rheumatoid arthritis

(2008) Ioannis Alexiou et al.   CLINICAL RHEUMATOLOGY

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice

(2008) Jonathan A. Hill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Orofacial granulomatosis - a 20-year review

(2008) B Grave et al.   ORAL DISEASES

Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

(2008) H. Sokol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptors and autoimmunity

(2007) Julia Hurst et al.   AUTOIMMUNITY REVIEWS