The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond
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Title
The incretin system ABCs in obesity and diabetes - novel therapeutic strategies for weight loss and beyond
Authors
Keywords
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Journal
Obesity Reviews
Volume 17, Issue 7, Pages 553-572
Publisher
Wiley
Online
2016-05-01
DOI
10.1111/obr.12421
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Note: Only part of the references are listed.- MK-0626, a selective DPP-4 inhibitor, attenuates hepatic steatosis inob/obmice
- (2016) Tatsuya Ohyama et al. WORLD JOURNAL OF GASTROENTEROLOGY
- DPP4 in Cardiometabolic Disease: Recent Insights From the Laboratory and Clinical Trials of DPP4 Inhibition
- (2015) J. Zhong et al. CIRCULATION RESEARCH
- An Updated Review on Cancer Risk Associated with Incretin Mimetics and Enhancers
- (2015) Chin-Hsiao Tseng et al. JOURNAL OF ENVIRONMENTAL SCIENCE AND HEALTH PART C-ENVIRONMENTAL CARCINOGENESIS & ECOTOXICOLOGY REVIEWS
- Glucagon-Like Peptide 1 Interacts with Ghrelin and Leptin to Regulate Glucose Metabolism and Food Intake through Vagal Afferent Neuron Signaling
- (2015) Charlotte C Ronveaux et al. JOURNAL OF NUTRITION
- Bariatric–metabolic surgery versus conventional medical treatment in obese patients with type 2 diabetes: 5 year follow-up of an open-label, single-centre, randomised controlled trial
- (2015) Geltrude Mingrone et al. LANCET
- Incretin-based therapies for obesity treatment
- (2015) Aline Haas de Mello et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Pharmacotherapy for the management of obesity
- (2015) Dhiren Patel METABOLISM-CLINICAL AND EXPERIMENTAL
- The complex immunological and inflammatory network of adipose tissue in obesity
- (2015) Vasso Apostolopoulos et al. MOLECULAR NUTRITION & FOOD RESEARCH
- A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management
- (2015) Xavier Pi-Sunyer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Appetite and body weight regulation after bariatric surgery
- (2015) H. Münzberg et al. Obesity Reviews
- The impact of bariatric surgery on quality of life: a systematic review and meta-analysis
- (2015) N. Lindekilde et al. Obesity Reviews
- Leptin resistance in diet-induced obesity: the role of hypothalamic inflammation
- (2015) K. C. G. de Git et al. Obesity Reviews
- Clinical Effectiveness of Exenatide in Diabetic Patients Waiting for Bariatric Surgery
- (2015) P. Iglesias et al. OBESITY SURGERY
- Detailed characterization of incretin cell distribution along the human small intestine
- (2015) Tiago P. Guedes et al. Surgery for Obesity and Related Diseases
- The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class?
- (2015) Ricardo Godinho et al. Journal of Diabetes Research
- Recent Advances in Dipeptidyl-Peptidase-4 Inhibition Therapy: Lessons from the Bench and Clinical Trials
- (2015) Jixin Zhong et al. Journal of Diabetes Research
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- (2015) Kristy M. Heppner et al. Frontiers in Neuroscience
- Monosodium Glutamate Dietary Consumption Decreases Pancreatic β-Cell Mass in Adult Wistar Rats
- (2015) Piyanard Boonnate et al. PLoS One
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- (2014) Andreia Gonçalves et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Do incretins improve endothelial function?
- (2014) Jun-ichi Oyama et al. Cardiovascular Diabetology
- Circadian Secretion of the Intestinal Hormone GLP-1 by the Rodent L Cell
- (2014) Manuel Gil-Lozano et al. DIABETES
- Ghrelin Is a Novel Regulator of GLP-1 Secretion
- (2014) Jeffrey Gagnon et al. DIABETES
- The Effects of Dipeptidyl Peptidase-4 Inhibition on Microvascular Diabetes Complications
- (2014) Angelo Avogaro et al. DIABETES CARE
- CXCL12 secreted from adipose tissue recruits macrophages and induces insulin resistance in mice
- (2014) Dayea Kim et al. DIABETOLOGIA
- Pharmacology, Physiology, and Mechanisms of Action of Dipeptidyl Peptidase-4 Inhibitors
- (2014) Erin E. Mulvihill et al. ENDOCRINE REVIEWS
- Prevention of Obesity-Induced Renal Injury in Male Mice by DPP4 Inhibition
- (2014) Ravi Nistala et al. ENDOCRINOLOGY
- The DPP-IV inhibitor linagliptin and GLP-1 induce synergistic effects on body weight loss and appetite suppression in the diet-induced obese rat
- (2014) Henrik H. Hansen et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Therapies for inter-relating diabetes and obesity – GLP-1 and obesity
- (2014) Eva W Iepsen et al. EXPERT OPINION ON PHARMACOTHERAPY
- The importance of weight management in type 2 diabetes mellitus
- (2014) J. P. H. Wilding INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
- Elimination and Degradation of Glucagon-like Peptide-1 and Glucose-Dependent Insulinotropic Polypeptide in Patients with End-Stage Renal Disease
- (2014) Thomas Idorn et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Sitagliptin Prevents Inflammation and Apoptotic Cell Death in the Kidney of Type 2 Diabetic Animals
- (2014) Catarina Marques et al. MEDIATORS OF INFLAMMATION
- Dipeptidyl peptidase inhibition prevents diastolic dysfunction and reduces myocardial fibrosis in a Mouse model of Western diet induced obesity
- (2014) Brian Bostick et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- DPP4 inhibition attenuates filtration barrier injury and oxidant stress in the zucker obese rat
- (2014) Ravi Nistala et al. Obesity
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- (2014) Hans Eickhoff et al. OBESITY SURGERY
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- (2014) Nattayaporn Apaijai et al. PLoS One
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- (2014) Edo Aarts et al. Surgery for Obesity and Related Diseases
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- (2013) Marcel H. A. Muskiet et al. Nature Reviews Nephrology
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- (2013) Takanobu Shimasaki et al. PLoS One
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- (2013) Regin Elsa George et al. SAUDI PHARMACEUTICAL JOURNAL
- Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: Incretin actions beyond the pancreas
- (2013) Yutaka Seino et al. Journal of Diabetes Investigation
- DPP-4 Inhibitors as Therapeutic Modulators of Immune Cell Function and Associated Cardiovascular and Renal Insulin Resistance in Obesity and Diabetes
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- The central GLP-1: implications for food and drug reward
- (2013) Karolina P. Skibicka Frontiers in Neuroscience
- The future role of gut hormones in the treatment of obesity
- (2013) Rachel C. Troke et al. Therapeutic Advances in Chronic Disease
- Review article: the emerging interplay among the gastrointestinal tract, bile acids and incretins in the pathogenesis of diabetes and non-alcoholic fatty liver disease
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- Colesevelam suppresses hepatic glycogenolysis by TGR5-mediated induction of GLP-1 action in DIO mice
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- Metabolic Syndrome, Insulin Resistance, and Roles of Inflammation – Mechanisms and Therapeutic Targets
- (2012) Giulio R. Romeo et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
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- (2012) Jixin Zhong et al. DIABETES
- Exenatide plus metformin compared with metformin alone on β-cell function in patients with Type 2 diabetes
- (2012) G. Derosa et al. DIABETIC MEDICINE
- Insulin resistance and cancer: the role of insulin and IGFs
- (2012) Sefirin Djiogue et al. ENDOCRINE-RELATED CANCER
- Ghrelin, the proglucagon-derived peptides and peptide YY in nutrient homeostasis
- (2012) Charlotte X. Dong et al. Nature Reviews Gastroenterology & Hepatology
- Bariatric Surgery versus Intensive Medical Therapy in Obese Patients with Diabetes
- (2012) Philip R. Schauer et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2012) P. M. M. Moraes-Vieira et al. Obesity Reviews
- Bile acid sequestrants
- (2011) Carolien Out et al. CURRENT OPINION IN LIPIDOLOGY
- Dipeptidyl Peptidase 4 Is a Novel Adipokine Potentially Linking Obesity to the Metabolic Syndrome
- (2011) D. Lamers et al. DIABETES
- Protective effects of the dipeptidyl peptidase IV inhibitor sitagliptin in the blood-retinal barrier in a type 2 diabetes animal model
- (2011) A. Gonçalves et al. DIABETES OBESITY & METABOLISM
- ESC/EAS Guidelines for the management of dyslipidaemias: The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS)
- (2011) et al. EUROPEAN HEART JOURNAL
- CD26/DPP-4 inhibition recruits regenerative stem cells via stromal cell-derived factor-1 and beneficially influences ischaemia-reperfusion injury in mouse lung transplantation
- (2011) W. Jungraithmayr et al. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
- Effects of GLP-1 and Incretin-Based Therapies on Gastrointestinal Motor Function
- (2011) Chinmay S. Marathe et al. Experimental Diabetes Research
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- (2011) Cristina Mega et al. Experimental Diabetes Research
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- (2011) B Laferrère INTERNATIONAL JOURNAL OF OBESITY
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- Is the GLP-1 system a viable therapeutic target for weight reduction?
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- (2010) G. P. Fadini et al. DIABETES CARE
- Albiglutide: a new GLP-1 analog for the treatment of type 2 diabetes
- (2010) Erin L St Onge et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- The bile acid receptor TGR5 (Gpbar-1) acts as a neurosteroid receptor in brain
- (2010) Verena Keitel et al. GLIA
- Interactive Hemodynamic Effects of Dipeptidyl Peptidase-IV Inhibition and Angiotensin-Converting Enzyme Inhibition in Humans
- (2010) Annis Marney et al. HYPERTENSION
- Effects of Sitagliptin Treatment on Dysmetabolism, Inflammation, and Oxidative Stress in an Animal Model of Type 2 Diabetes (ZDF Rat)
- (2010) Liliana Ferreira et al. MEDIATORS OF INFLAMMATION
- SDF-1 provides morphological and functional protection against renal ischaemia/reperfusion injury
- (2010) G. Stokman et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- GIP and GLP-1, the two incretin hormones: Similarities and differences
- (2010) Yutaka Seino et al. Journal of Diabetes Investigation
- Mechanisms underlying the rapid degradation and elimination of the incretin hormones GLP-1 and GIP
- (2009) Rolf Mentlein BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Synergy between CD26/DPP-IV Inhibition and G-CSF Improves Cardiac Function after Acute Myocardial Infarction
- (2009) Marc-Michael Zaruba et al. Cell Stem Cell
- DPP-IV inhibition enhances the antilipolytic action of NPY in human adipose tissue
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- The Omentum: Anatomical, Metabolic, and Surgical Aspects
- (2009) Danielle Collins et al. JOURNAL OF GASTROINTESTINAL SURGERY
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- (2008) Darleen Sandoval PHYSIOLOGY & BEHAVIOR
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- (2007) Aine M. McKillop et al. DIABETES RESEARCH AND CLINICAL PRACTICE
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