Phytochemicals as novel agents for the induction of browning in white adipose tissue

Characterizing active and inactive brown adipose tissue in adult humans using PET-CT and MR imaging

(2016) Aliya Gifford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Hormonal and nutritional signalling in the control of brown and beige adipose tissue activation and recruitment

(2016) Marta Giralt et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

Capsaicin induces browning of white adipose tissue and counters obesity by activating TRPV1 channel-dependent mechanisms

(2016) Padmamalini Baskaran et al.   BRITISH JOURNAL OF PHARMACOLOGY

Direct action of capsaicin in brown adipogenesis and activation of brown adipocytes

(2016) Ryosuke Kida et al.   CELL BIOCHEMISTRY AND FUNCTION

A Synergistic Antiobesity Effect by a Combination of Capsinoids and Cold Temperature Through Promoting Beige Adipocyte Biogenesis

(2016) Kana Ohyama et al.   DIABETES

Uncoupling Proteins and the Molecular Mechanisms of Thyroid Thermogenesis

(2016) A. Solmonson et al.   ENDOCRINOLOGY

Curcumin induces brown fat-like phenotype in 3T3-L1 and primary white adipocytes

(2016) Jameel Lone et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde

(2016) Akshay Jawale et al.   PHYTOMEDICINE

Probiotic Soy Product Supplemented with Isoflavones Improves the Lipid Profile of Moderately Hypercholesterolemic Men: A Randomized Controlled Trial

(2016) Daniela Cardoso Umbelino Cavallini et al.   Nutrients

Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way

(2015) Shan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Brown adipose tissue activity as a target for the treatment of obesity/insulin resistance

(2015) Anne-Laure Poher et al.   Frontiers in Physiology

Matured Hop Bittering Components Induce Thermogenesis in Brown Adipose Tissue via Sympathetic Nerve Activity

(2015) Yumie Morimoto-Kobayashi et al.   PLoS One

Naringenin suppresses macrophage infiltration into adipose tissue in an early phase of high-fat diet-induced obesity

(2014) Hiroki Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Natural product agonists of peroxisome proliferator-activated receptor gamma (PPARγ): a review

(2014) Limei Wang et al.   BIOCHEMICAL PHARMACOLOGY

Nutraceuticals and regulation of adipocyte life: Premises or promises

(2014) Monica Colitti et al.   BIOFACTORS

Soy and the soy isoflavone genistein promote adipose tissue development in male mice on a low-fat diet

(2014) Isabella Zanella et al.   EUROPEAN JOURNAL OF NUTRITION

Resveratrol increases brown adipose tissue thermogenesis markers by increasing SIRT1 and energy expenditure and decreasing fat accumulation in adipose tissue of mice fed a standard diet

(2014) João Marcus Oliveira Andrade et al.   EUROPEAN JOURNAL OF NUTRITION

Obesity and Its Metabolic Complications: The Role of Adipokines and the Relationship between Obesity, Inflammation, Insulin Resistance, Dyslipidemia and Nonalcoholic Fatty Liver Disease

(2014) Un Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1

(2014) Jing Dong et al.   JOURNAL OF LIPID RESEARCH

Effects of Xanthohumol-rich Extract from the Hop on Fatty Acid Metabolism in Rats Fed a High-fat Diet

(2014) Kazuki Yui et al.   Journal of Oleo Science

Effects of Xanthohumol-Rich Hop Extract on the Differentiation of Preadipocytes

(2014) Ayane Kiyofuji et al.   Journal of Oleo Science

Impact of Soy Isoflavones on the Epigenome in Cancer Prevention

(2014) Maria Pudenz et al.   Nutrients

A New Era in Brown Adipose Tissue Biology: Molecular Control of Brown Fat Development and Energy Homeostasis

(2013) Shingo Kajimura et al.   Annual Review of Physiology

Anatomical Locations of Human Brown Adipose Tissue: Functional Relevance and Implications in Obesity and Type 2 Diabetes

(2013) H. Sacks et al.   DIABETES

Antiobesity effects of quercetin-rich onion peel extract on the differentiation of 3T3-L1 preadipocytes and the adipogenesis in high fat-fed rats

(2013) Jiyoung Moon et al.   FOOD AND CHEMICAL TOXICOLOGY

Thermogenesis is involved in the body-fat lowering effects of resveratrol in rats

(2013) Goiuri Alberdi et al.   FOOD CHEMISTRY

A Metabolomics-driven Elucidation of the Anti-obesity Mechanisms of Xanthohumol

(2013) Jay S. Kirkwood et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The bile acid membrane receptor TGR5: a novel pharmacological target in metabolic, inflammatory and neoplastic disorders

(2013) Vanesa Stepanov et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Brown and beige fat: development, function and therapeutic potential

(2013) Matthew Harms et al.   NATURE MEDICINE

Curcumin acts via transient receptor potential vanilloid-1 receptors to inhibit gut nociception and reverses visceral hyperalgesia

(2013) L. Zhi et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The extract ofCinnamomum cassiatwigs inhibits adipocyte differentiation via activation of the insulin signaling pathway in 3T3-L1 preadipocytes

(2013) Yunkyung Han et al.   PHARMACEUTICAL BIOLOGY

Brown Adipose Tissue as a Regulator of Energy Expenditure and Body Fat in Humans

(2013) Masayuki Saito   Diabetes & Metabolism Journal

Nonpungent capsaicin analogs (capsinoids) increase energy expenditure through the activation of brown adipose tissue in humans

(2012) Takeshi Yoneshiro et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Adipogenesis: From Stem Cell to Adipocyte

(2012) Qi Qun Tang et al.   Annual Review of Biochemistry

Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ

(2012) Li Qiang et al.   CELL

SIRT1 Is Required for AMPK Activation and the Beneficial Effects of Resveratrol on Mitochondrial Function

(2012) Nathan L. Price et al.   Cell Metabolism

Naringenin prevents cholesterol-induced systemic inflammation, metabolic dysregulation, and atherosclerosis inLdlr−/−mice

(2012) Julia M. Assini et al.   JOURNAL OF LIPID RESEARCH

Ingestion of Cinnamaldehyde, a TRPA1 Agonist, Reduces Visceral Fats in Mice Fed a High-Fat and High-Sucrose Diet

(2012) Yasuko TAMURA et al.   JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY

Quercetin Reduces High-Fat Diet-Induced Fat Accumulation in the Liver by Regulating Lipid Metabolism Genes

(2012) Chang Hwa Jung et al.   PHYTOTHERAPY RESEARCH

Development of insulin resistance in mice lacking PGC-1  in adipose tissues

(2012) S. Kleiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phytochemicals and their impact on adipose tissue inflammation and diabetes

(2012) Andreas Leiherer et al.   VASCULAR PHARMACOLOGY

Fucoxanthin exerts differing effects on 3T3-L1 cells according to differentiation stage and inhibits glucose uptake in mature adipocytes

(2011) Seong-Il Kang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Plac8 Is an Inducer of C/EBPβ Required for Brown Fat Differentiation, Thermoregulation, and Control of Body Weight

(2011) Maria Jimenez-Preitner et al.   Cell Metabolism

Novel molecular targets for prevention of obesity and osteoporosis

(2011) Srujana Rayalam et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The T3Receptor β1 Isoform Regulates UCP1 and D2 Deiodinase in Rat Brown Adipocytes

(2010) Raquel Martinez de Mena et al.   ENDOCRINOLOGY

Dietary naringenin increases hepatic peroxisome proliferators–activated receptor α protein expression and decreases plasma triglyceride and adiposity in rats

(2010) Kae Won Cho et al.   EUROPEAN JOURNAL OF NUTRITION

Adipose tissue macrophages: their role in adipose tissue remodeling

(2010) Takayoshi Suganami et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Flavonols and cardiovascular disease

(2010) Francisco Perez-Vizcaino et al.   MOLECULAR ASPECTS OF MEDICINE

Xanthohumol, a prenylated chalcone from hops, modulates hepatic expression of genes involved in thyroid hormone distribution and metabolism

(2010) Branislav Radović et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Hypothalamic AMPK and fatty acid metabolism mediate thyroid regulation of energy balance

(2010) Miguel López et al.   NATURE MEDICINE

Intragastric Administration of TRPV1, TRPV3, TRPM8, and TRPA1 Agonists Modulates Autonomic Thermoregulation in Different Manners in Mice

(2009) Yukiko MASAMOTO et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Non-Pungent Capsaicin Analogs (Capsinoids) Increase Metabolic Rate and Enhance ThermogenesisviaGastrointestinal TRPV1 in Mice

(2009) Fuminori KAWABATA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Naringenin Prevents Dyslipidemia, Apolipoprotein B Overproduction, and Hyperinsulinemia in LDL Receptor-Null Mice With Diet-Induced Insulin Resistance

(2009) E. E. Mulvihill et al.   DIABETES

AMP-Activated Protein Kinase-Deficient Mice Are Resistant to the Metabolic Effects of Resveratrol

(2009) J.-H. Um et al.   DIABETES

The effects of Xanthigen™in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat

(2009) M. Abidov et al.   DIABETES OBESITY & METABOLISM

Effects of guggulsterone isolated from Commiphora mukul in high fat diet induced diabetic rats

(2009) Bhavna Sharma et al.   FOOD AND CHEMICAL TOXICOLOGY

Transcriptional control of brown adipocyte development and physiological function--of mice and men

(2009) P. Seale et al.   GENES & DEVELOPMENT

Anti-Obesity Effects of Xanthohumol Plus Guggulsterone in 3T3-L1 Adipocytes

(2009) Srujana Rayalam et al.   JOURNAL OF MEDICINAL FOOD

Curcumin Inhibits Adipogenesis in 3T3-L1 Adipocytes and Angiogenesis and Obesity in C57/BL Mice

(2009) Asma Ejaz et al.   JOURNAL OF NUTRITION

Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model

(2009) Maeda   Molecular Medicine Reports

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Identification and Importance of Brown Adipose Tissue in Adult Humans

(2009) Aaron M. Cypess et al.   NEW ENGLAND JOURNAL OF MEDICINE

TRPA1 Agonists—Allyl Isothiocyanate and Cinnamaldehyde—Induce Adrenaline Secretion

(2008) Yusaku IWASAKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Combined Effects of Genistein, Quercetin, and Resveratrol in Human and 3T3-L1 Adipocytes

(2008) Hea Jin Park et al.   JOURNAL OF MEDICINAL FOOD

Phytochemicals and regulation of the adipocyte life cycle☆

(2008) S RAYALAM et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Isoflavones Promote Mitochondrial Biogenesis

(2008) K. A. Rasbach et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Quercetin transiently increases energy expenditure but persistently decreases circulating markers of inflammation in C57BL/6J mice fed a high-fat diet

(2008) Laura K. Stewart et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabeticdb/dbmice

(2008) Kwon-Il Seo et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Guggulsterone Inhibits Adipocyte Differentiation and Induces Apoptosis in 3T3-L1 Cells

(2008) Jeong-Yeh Yang et al.   Obesity

Quercetin Ameliorates Metabolic Syndrome and Improves the Inflammatory Status in Obese Zucker Rats

(2008) Leonor Rivera et al.   Obesity

Resveratrol induces apoptosis and inhibits adipogenesis in 3T3-L1 adipocytes

(2008) Srujana Rayalam et al.   PHYTOTHERAPY RESEARCH

Genistein suppresses adipogenesis of 3T3-L1 cells via multiple signal pathways

(2008) Meng Zhang et al.   PHYTOTHERAPY RESEARCH