Role of neuroinflammation and latent transcription factors in pathogenesis of Parkinson’s disease

Unknown

(2018)   HUMAN MUTATION

Pharmacological and biochemical studies on the protective effects of melatonin during stress-induced behavioral and immunological changes in relation to oxidative stress in rats

(2016) Rishi Pal et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Unknown

(2016)   JOURNAL OF NEUROCHEMISTRY

Unknown

(2016)   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Dopamine Controls Systemic Inflammation through Inhibition of NLRP3 Inflammasome

(2015) Yiqing Yan et al.   CELL

Protective role of theophylline and their interaction with nitric oxide (NO) in adjuvant-induced rheumatoid arthritis in rats

(2015) Rishi Pal et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Inflammation is genetically implicated in Parkinson’s disease

(2015) N. Dzamko et al.   NEUROSCIENCE

The role of inflammasome in Alzheimer's disease

(2014) Li Liu et al.   AGEING RESEARCH REVIEWS

Comparable Autoantibody Serum Levels against Amyloid- and Inflammation-Associated Proteins in Parkinson’s Disease Patients and Controls

(2014) Walter Maetzler et al.   PLoS One

RTP801/REDD1: a stress coping regulator that turns into a troublemaker in neurodegenerative disorders

(2014) Mercè Canal et al.   Frontiers in Cellular Neuroscience

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

(2014) Ricardo Cabezas et al.   Frontiers in Cellular Neuroscience

Inflammasomes in neuroinflammation and changes in brain function: a focused review

(2014) Gaurav Singhal et al.   Frontiers in Neuroscience

Association of Parkinson Disease with Structural and Regulatory Variants in the HLA Region

(2013) William T. Wissemann et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Role of enteric neurotransmission in host defense and protection of the gastrointestinal tract

(2013) Keith A. Sharkey et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia

(2013) Piotr Przanowski et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Activation of microglia induces symptoms of Parkinson’s disease in wild-type, but not in IL-1 knockout mice

(2013) Sachiko Tanaka et al.   Journal of Neuroinflammation

MHCII Is Required for  -Synuclein-Induced Activation of Microglia, CD4 T Cell Proliferation, and Dopaminergic Neurodegeneration

(2013) A. S. Harms et al.   JOURNAL OF NEUROSCIENCE

DJ-1 facilitates the interaction between STAT1 and its phosphatase, SHP-1, in brain microglia and astrocytes: A novel anti-inflammatory function of DJ-1

(2013) Jong-hyeon Kim et al.   NEUROBIOLOGY OF DISEASE

Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells

(2013) E. R. Andersson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

(2012) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Protosappanin A inhibits oxidative and nitrative stress via interfering the interaction of transmembrane protein CD14 with Toll-like receptor-4 in lipopolysaccharide-induced BV-2 microglia

(2012) Ke-Wu Zeng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Activation of Wnt/β-catenin Pathway by Exogenous Wnt1 Protects SH-SY5Y Cells Against 6-Hydroxydopamine Toxicity

(2012) Lei Wei et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Extensive innate immune gene activation accompanies brain aging, increasing vulnerability to cognitive decline and neurodegeneration: a microarray study

(2012) David H Cribbs et al.   Journal of Neuroinflammation

LRRK2 Inhibition Attenuates Microglial Inflammatory Responses

(2012) M. S. Moehle et al.   JOURNAL OF NEUROSCIENCE

Understanding the molecular basis of MK2–p38α signaling complex assembly: insights into protein–protein interaction by molecular dynamics and free energy studies

(2012) Ying Yang et al.   Molecular BioSystems

Association between Parkinson's disease and the HLA-DRB1 locus

(2012) Ismaïl Ahmed et al.   MOVEMENT DISORDERS

Colonic inflammation in Parkinson's disease

(2012) David Devos et al.   NEUROBIOLOGY OF DISEASE

Parkinson's disease-linked leucine-rich repeat kinase 2(R1441G) mutation increases proinflammatory cytokine release from activated primary microglial cells and resultant neurotoxicity

(2012) F. Gillardon et al.   NEUROSCIENCE

Inhibition of the canonical Wnt pathway by Dickkopf-1 contributes to the neurodegeneration in 6-OHDA-lesioned rats

(2012) Yaoyan Dun et al.   NEUROSCIENCE LETTERS

In vivo microglia activation in very early dementia with Lewy bodies, comparison with Parkinson's disease

(2012) S. Iannaccone et al.   PARKINSONISM & RELATED DISORDERS

Concordant Signaling Pathways Produced by Pesticide Exposure in Mice Correspond to Pathways Identified in Human Parkinson's Disease

(2012) Seema Gollamudi et al.   PLoS One

Non-Motor Symptoms in Patients with Parkinson’s Disease – Correlations with Inflammatory Cytokines in Serum

(2012) Daniel Lindqvist et al.   PLoS One

ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo

(2012) Carlos Barcia et al.   Scientific Reports

ULK1 inhibits the kinase activity of mTORC1 and cell proliferation

(2011) Chang Hwa Jung et al.   Autophagy

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

(2011) Lana J Mawhinney et al.   BMC NEUROSCIENCE

Pharmacological and biochemical studies on the role of free radicals during stress-induced immunomodulation in rats

(2011) Rishi Pal et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Glia: Initiators and progressors of pathology in Parkinson's disease

(2011) Glenda M. Halliday et al.   MOVEMENT DISORDERS

Neurotoxin-based models of Parkinson's disease

(2011) J. Bové et al.   NEUROSCIENCE

Increased Intestinal Permeability Correlates with Sigmoid Mucosa alpha-Synuclein Staining and Endotoxin Exposure Markers in Early Parkinson's Disease

(2011) Christopher B. Forsyth et al.   PLoS One

Mechanisms and functions of p38 MAPK signalling

(2010) Ana Cuadrado et al.   BIOCHEMICAL JOURNAL

TAK1 targeting by glucocorticoids determines JNK and I B regulation in Toll-like receptor-stimulated macrophages

(2010) S. Bhattacharyya et al.   BLOOD

Gene expression profiling in progressively MPTP-lesioned macaques reveals molecular pathways associated with sporadic Parkinson's disease

(2010) Tatsuya Ohnuki et al.   BRAIN RESEARCH

MK2 Signaling: Lessons on Tissue Specificity in Modulation of Inflammation

(2010) Nanna Fyhrquist et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Reactive astrocytes and Wnt/β-catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

(2010) F. L'Episcopo et al.   NEUROBIOLOGY OF DISEASE

NF-κB Signaling: A Tale of Two Pathways in Skeletal Myogenesis

(2010) Nadine Bakkar et al.   PHYSIOLOGICAL REVIEWS

Parkinson's Disease

(2009) Christopher H. Hawkes et al.   Annals of the New York Academy of Sciences

Dissecting the role of mTOR: Lessons from mTOR inhibitors

(2009) Ryan J.O. Dowling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Mammalian target of rapamycin complex 1: Signalling inputs, substrates and feedback mechanisms

(2009) E.A. Dunlop et al.   CELLULAR SIGNALLING

TOR-dependent control of autophagy: biting the hand that feeds

(2009) Thomas P Neufeld   CURRENT OPINION IN CELL BIOLOGY

The resolution of inflammation: Anti-inflammatory roles for NF-κB

(2009) Toby Lawrence et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Phosphorylation of Neuronal Survival Factor MEF2D by Glycogen Synthase Kinase 3β in Neuronal Apoptosis

(2009) Xuemin Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Peripheral Chemo-Cytokine Profiles in Alzheimers and Parkinsons Diseases

(2009) M. Reale et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Inflammation in Alzheimer's disease: Amyloid-β oligomers trigger innate immunity defence via pattern recognition receptors

(2009) Antero Salminen et al.   PROGRESS IN NEUROBIOLOGY

Regulation of Neuronal Survival Factor MEF2D by Chaperone-Mediated Autophagy

(2009) Q. Yang et al.   SCIENCE

mTOR signaling: At the crossroads of plasticity, memory and disease

(2009) Charles A. Hoeffer et al.   TRENDS IN NEUROSCIENCES

A Structural Guide to Proteins of the NF- B Signaling Module

(2009) T. Huxford et al.   Cold Spring Harbor Perspectives in Biology

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

Variation in the miRNA-433 Binding Site of FGF20 Confers Risk for Parkinson Disease by Overexpression of α-Synuclein

(2008) Gaofeng Wang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's disease

(2008) M. C. Pott Godoy et al.   BRAIN

The α-synuclein burden hypothesis of Parkinson disease and its relationship to Alzheimer disease

(2008) Patrick L. McGeer et al.   EXPERIMENTAL NEUROLOGY

Age and region-specific responses of microglia, but not astrocytes, suggest a role in selective vulnerability of dopamine neurons after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure in monkeys

(2008) Nicholas M. Kanaan et al.   GLIA

Wnt5a-treated midbrain neural stem cells improve dopamine cell replacement therapy in parkinsonian mice

(2008) Clare L. Parish et al.   JOURNAL OF CLINICAL INVESTIGATION

Age-related changes in glial cells of dopamine midbrain subregions in rhesus monkeys

(2008) Nicholas M. Kanaan et al.   NEUROBIOLOGY OF AGING

Fas-associated factor 1 and Parkinson's disease

(2008) Ranjita Betarbet et al.   NEUROBIOLOGY OF DISEASE

The roles of the classical and alternative nuclear factor-kappaB pathways: potential implications for autoimmunity and rheumatoid arthritis

(2008) Keith D Brown et al.   ARTHRITIS RESEARCH & THERAPY