Meta-analysis of dispensable essential genes and their interactions with bypass suppressors

Rapid Intraspecies Evolution of Fitness Effects of Yeast Genes

(2022) Yayu Wang et al.   Genome Biology and Evolution

Transposon insertional mutagenesis of diverse yeast strains suggests coordinated gene essentiality polymorphisms

(2022) Piaopiao Chen et al.   Nature Communications

Analysing the yeast complexome—the Complex Portal rising to the challenge

(2021) Birgit H M Meldal et al.   NUCLEIC ACIDS RESEARCH

Fission stories: using PomBase to understand Schizosaccharomyces pombe biology

(2021) Midori A Harris et al.   GENETICS

Systematic analysis of bypass suppression of essential genes

(2020) Jolanda Leeuwen et al.   Molecular Systems Biology

PANTHER version 16: a revised family classification, tree-based classification tool, enhancer regions and extensive API

(2020) Huaiyu Mi et al.   NUCLEIC ACIDS RESEARCH

UniProt: the universal protein knowledgebase in 2021

(2020) et al.   NUCLEIC ACIDS RESEARCH

Transposon insertional mutagenesis in Saccharomyces uvarum reveals trans-acting effects influencing species-dependent essential genes

(2019) Monica R. Sanchez et al.   GENOME RESEARCH

Systematic analysis reveals the prevalence and principles of bypassable gene essentiality

(2019) Jun Li et al.   Nature Communications

Prioritization of cancer therapeutic targets using CRISPR–Cas9 screens

(2019) Fiona M. Behan et al.   NATURE

The pan-genome of Saccharomyces cerevisiae

(2019) Gang Li et al.   FEMS YEAST RESEARCH

SonicParanoid: fast, accurate, and easy orthology inference

(2018) Salvatore Cosentino et al.   BIOINFORMATICS

High-dimensional single-cell phenotyping reveals extensive haploinsufficiency

(2018) Shinsuke Ohnuki et al.   PLOS BIOLOGY

Unification of Protein Abundance Datasets Yields a Quantitative Saccharomyces cerevisiae Proteome

(2018) Brandon Ho et al.   Cell Systems

Genome evolution across 1,011 Saccharomyces cerevisiae isolates

(2018) Jackson Peter et al.   NATURE

Gene Essentiality Analyzed by In Vivo Transposon Mutagenesis and Machine Learning in a Stable Haploid Isolate of Candida albicans

(2018) Ella Shtifman Segal et al.   mBio

Computational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells

(2017) Robin M Meyers et al.   NATURE GENETICS

Emerging and evolving concepts in gene essentiality

(2017) Giulia Rancati et al.   NATURE REVIEWS GENETICS

TheCellMap.org: A Web-Accessible Database for Visualizing and Mining the Global Yeast Genetic Interaction Network

(2017) Matej Usaj et al.   G3-Genes Genomes Genetics

Efficient randomization of biological networks while preserving functional characterization of individual nodes

(2016) Francesco Iorio et al.   BMC BIOINFORMATICS

Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases

(2016) Rong Chen et al.   NATURE BIOTECHNOLOGY

Design and synthesis of a minimal bacterial genome

(2016) C. A. Hutchison et al.   SCIENCE

Exploring genetic suppression interactions on a global scale

(2016) J. van Leeuwen et al.   SCIENCE

A global genetic interaction network maps a wiring diagram of cellular function

(2016) M. Costanzo et al.   SCIENCE

Predicting Essential Genes and Proteins Based on Machine Learning and Network Topological Features: A Comprehensive Review

(2016) Xue Zhang et al.   Frontiers in Physiology

Gene Essentiality Is a Quantitative Property Linked to Cellular Evolvability

(2015) Gaowen Liu et al.   CELL

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities

(2015) Traver Hart et al.   CELL

Identification of cis-suppression of human disease mutations by comparative genomics

(2015) Daniel M. Jordan et al.   NATURE

KEGG as a reference resource for gene and protein annotation

(2015) Minoru Kanehisa et al.   NUCLEIC ACIDS RESEARCH

Characteristics of Plant Essential Genes Allow for within- and between-Species Prediction of Lethal Mutant Phenotypes

(2015) John P. Lloyd et al.   PLANT CELL

Gene essentiality and synthetic lethality in haploid human cells

(2015) V. A. Blomen et al.   SCIENCE

Identification and characterization of essential genes in the human genome

(2015) T. Wang et al.   SCIENCE

Evolutionary conservation analysis between the essential and nonessential genes in bacterial genomes

(2015) Hao Luo et al.   Scientific Reports

Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities

(2015) Kamesh Narasimhan et al.   eLife

Detecting epistasis in human complex traits

(2014) Wen-Hua Wei et al.   NATURE REVIEWS GENETICS

InParanoid 8: orthology analysis between 273 proteomes, mostly eukaryotic

(2014) Erik L.L. Sonnhammer et al.   NUCLEIC ACIDS RESEARCH

Global Proteome Turnover Analyses of the Yeasts S. cerevisiae and S. pombe

(2014) Romain Christiano et al.   Cell Reports

Epistasis and quantitative traits: using model organisms to study gene–gene interactions

(2013) Trudy F. C. Mackay   NATURE REVIEWS GENETICS

Interaction landscape of membrane-protein complexes in Saccharomyces cerevisiae

(2012) Mohan Babu et al.   NATURE

D2P2: database of disordered protein predictions

(2012) Matt E. Oates et al.   NUCLEIC ACIDS RESEARCH

Patterns of Evolutionary Conservation of Essential Genes Correlate with Their Compensability

(2012) Tobias Bergmiller et al.   PLoS Genetics

Conserved rules govern genetic interaction degree across species

(2012) Elizabeth N Koch et al.   GENOME BIOLOGY

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

Saccharomyces Genome Database: the genomics resource of budding yeast

(2011) J. M. Cherry et al.   NUCLEIC ACIDS RESEARCH

PomBase: a comprehensive online resource for fission yeast

(2011) V. Wood et al.   NUCLEIC ACIDS RESEARCH

Essence of life: essential genes of minimal genomes

(2011) Mario Juhas et al.   TRENDS IN CELL BIOLOGY

Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast

(2010) Norman Pavelka et al.   NATURE

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

(2010) Dong-Uk Kim et al.   NATURE BIOTECHNOLOGY

Investigating the predictability of essential genes across distantly related organisms using an integrative approach

(2010) Jingyuan Deng et al.   NUCLEIC ACIDS RESEARCH

Genotype to Phenotype: A Complex Problem

(2010) R. D. Dowell et al.   SCIENCE

The Genetic Landscape of a Cell

(2010) M. Costanzo et al.   SCIENCE

Predicting essential genes based on network and sequence analysis

(2009) Yih-Chii Hwang et al.   Molecular BioSystems

Quantification of the yeast transcriptome by single-molecule sequencing

(2009) Doron Lipson et al.   NATURE BIOTECHNOLOGY

Determining Protein Complex Connectivity Using a Probabilistic Deletion Network Derived from Quantitative Proteomics

(2009) Mihaela E. Sardiu et al.   PLoS One