Analysis of the Effect of the TRPC4/TRPC5 Blocker, ML204, in Sucrose-Induced Metabolic Imbalance

Different carbohydrate exposures and weight gain—results from a pooled analysis of three population-based studies

(2023) Rilla Tammi et al.   INTERNATIONAL JOURNAL OF OBESITY

Dietary sugar consumption and health: umbrella review

(2023) Yin Huang et al.   BMJ-British Medical Journal

The role of sugar-sweetened beverages in the global epidemics of obesity and chronic diseases

(2022) Vasanti S. Malik et al.   Nature Reviews Endocrinology

Role of mechanosensitive channels/receptors in atherosclerosis

(2022) Pritha Mukherjee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

An Overview of the TRP-Oxidative Stress Axis in Metabolic Syndrome: Insights for Novel Therapeutic Approaches

(2022) Mizael C. Araújo et al.   Cells

Global, regional, and country estimates of metabolic syndrome burden in children and adolescents in 2020: a systematic review and modelling analysis

(2022) Jean Jacques Noubiap et al.   Lancet Child & Adolescent Health

A High-Sugar Diet Consumption, Metabolism and Health Impacts with a Focus on the Development of Substance Use Disorder: A Narrative Review

(2022) Kacper Witek et al.   Nutrients

A high sucrose diet modifies brain oxylipins in a sex-dependent manner

(2022) Jennifer E. Norman et al.   PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS

Transient Receptor Potential (TRP) Channels in Airway Toxicity and Disease: An Update

(2022) Isabel Müller et al.   Cells

Fructose- and sucrose- but not glucose-sweetened beverages promote hepatic de novo lipogenesis: A randomized controlled trial

(2021) Bettina Geidl-Flueck et al.   JOURNAL OF HEPATOLOGY

Advances in TRP channel drug discovery: from target validation to clinical studies

(2021) Ari-Pekka Koivisto et al.   NATURE REVIEWS DRUG DISCOVERY

Thermosensory Transient Receptor Potential Ion Channels and Asthma

(2021) Oxana Yu. Kytikova et al.   Biomedicines

Wegovy (semaglutide): a new weight loss drug for chronic weight management

(2021) Gurdeep Singh et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo

(2021) Yanbin Dong et al.   Molecular Metabolism

Dietary sucrose induces metabolic inflammation and atherosclerotic cardiovascular diseases more than dietary fat in LDLr ApoB100/100 mice

(2020) Laís R. Perazza et al.   ATHEROSCLEROSIS

Trends in the Prevalence of Metabolic Syndrome in the United States, 2011-2016

(2020) Grishma Hirode et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Post-weaning exposure to high-sucrose diet induces early non-alcoholic fatty liver disease onset and progression in male mice: role of dysfunctional white adipose tissue

(2020) Lucas Martins França et al.   Journal of Developmental Origins of Health and Disease

Reporting animal research: Explanation and elaboration for the ARRIVE guidelines 2.0

(2020) Nathalie Percie du Sert et al.   PLOS BIOLOGY

Rutaecarpine ameliorated high sucrose-induced Alzheimer's disease like pathological and cognitive impairments in mice

(2020) Bin Zhao et al.   REJUVENATION RESEARCH

Transient Receptor Potential Canonical (TRPC) Channels: Then and Now

(2020) Xingjuan Chen et al.   Cells

Ces1d deficiency protects against high-sucrose diet-induced hepatic triacylglycerol accumulation

(2019) Jihong Lian et al.   JOURNAL OF LIPID RESEARCH

Direct and indirect effects of liraglutide on hypothalamic POMC and NPY/AgRP neurons – Implications for energy balance and glucose control

(2019) Zhenyan He et al.   Molecular Metabolism

A high-sucrose diet aggravates Alzheimer's disease pathology, attenuates hypothalamic leptin signaling, and impairs food-anticipatory activity in APPswe/PS1dE9 mice

(2019) Skye Hsin-Hsien Yeh et al.   NEUROBIOLOGY OF AGING

Inhibition of Canonical Transient Receptor Potential 5 Channels Polarizes Macrophages to an M1 Phenotype

(2019) Lerong Tao et al.   PHARMACOLOGY

Liquid Sucrose Consumption Promotes Obesity and Impairs Glucose Tolerance Without Altering Circulating Insulin Levels

(2018) Susan J. Burke et al.   Obesity

Transient receptor potential (TRP) channels: a metabolic TR(i)P to obesity prevention and therapy

(2018) M. Bishnoi et al.   Obesity Reviews

Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice

(2018) Domingos M. S. Pereira et al.   Oxidative Medicine and Cellular Longevity

Long-term exposure to high-sucrose diet downregulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice

(2018) Karla Frida Torres Flister et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Long-term high-protein diet intake reverts weight gain and attenuates metabolic dysfunction on high-sucrose-fed adult rats

(2018) Rosângela Maria Lopes Sousa et al.   Nutrition & Metabolism

TRP channels in cardiac and intestinal fibrosis

(2018) Ryuji Inoue et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Food Groups and Risk of Overweight, Obesity, and Weight Gain: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies

(2018) Sabrina Schlesinger et al.   Advances in Nutrition

Transient receptor potential canonical 5 (TRPC5) protects against pain and vascular inflammation in arthritis and joint inflammation

(2016) Khadija M Alawi et al.   ANNALS OF THE RHEUMATIC DISEASES

Raspberry seed flour attenuates high-sucrose diet-mediated hepatic stress and adipose tissue inflammation

(2016) Inhae Kang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sugar consumption, metabolic disease and obesity: The state of the controversy

(2015) Kimber L. Stanhope   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

A Longitudinal Analysis of Sugar-Sweetened Beverage Intake in Infancy and Obesity at 6 Years

(2014) L. Pan et al.   PEDIATRICS

Adipose Vascular Endothelial Growth Factor Regulates Metabolic Homeostasis through Angiogenesis

(2013) Hoon-Ki Sung et al.   Cell Metabolism

Constitutively Active TRPC Channels of Adipocytes Confer a Mechanism for Sensing Dietary Fatty Acids and Regulating Adiponectin

(2012) Piruthivi Sukumar et al.   CIRCULATION RESEARCH

Adipose Tissue Overexpression of Vascular Endothelial Growth Factor Protects Against Diet-Induced Obesity and Insulin Resistance

(2012) I. Elias et al.   DIABETES

Moderate Amounts of Fructose Consumption Impair Insulin Sensitivity in Healthy Young Men: A randomized controlled trial

(2012) I. Aeberli et al.   DIABETES CARE

A Role for TRPV1 in Influencing the Onset of Cardiovascular Disease in Obesity

(2012) Nichola J. Marshall et al.   HYPERTENSION

Drosophila TRP channels and animal behavior

(2012) Melissa A. Fowler et al.   LIFE SCIENCES

Low to moderate sugar-sweetened beverage consumption impairs glucose and lipid metabolism and promotes inflammation in healthy young men: a randomized controlled trial

(2011) Isabelle Aeberli et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sucrose-sweetened beverages increase fat storage in the liver, muscle, and visceral fat depot: a 6-mo randomized intervention study

(2011) Maria Maersk et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Identification of ML204, a Novel Potent Antagonist That Selectively Modulates Native TRPC4/C5 Ion Channels

(2011) Melissa Miller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

International Union of Basic and Clinical Pharmacology. LXXVI. Current Progress in the Mammalian TRP Ion Channel Family

(2010) L.-J. Wu et al.   PHARMACOLOGICAL REVIEWS