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Title
IAP antagonists induce anti-tumor immunity in multiple myeloma
Authors
Keywords
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Journal
NATURE MEDICINE
Volume 22, Issue 12, Pages 1411-1420
Publisher
Springer Nature
Online
2016-11-15
DOI
10.1038/nm.4229
References
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- (2016) A C West et al. Oncogenesis
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- (2014) Anders A. Tveita et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2014) Jeffrey R. Infante et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibitor of apoptosis proteins as therapeutic targets in multiple myeloma
- (2014) V Ramakrishnan et al. LEUKEMIA
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- (2012) M. Chesi et al. BLOOD
- Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells
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- Blockade of inhibitors of apoptosis (IAPs) in combination with tumor-targeted delivery of tumor necrosis factor-α leads to synergistic antitumor activity
- (2012) Z Yuan et al. CANCER GENE THERAPY
- Inhibitor of apoptosis protein (IAP) antagonists demonstrate divergent immunomodulatory properties in human immune subsets with implications for combination therapy
- (2012) Ashley J. Knights et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Continuous Lenalidomide Treatment for Newly Diagnosed Multiple Myeloma
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- (2012) Ethan Cerami et al. Cancer Discovery
- Cyclophosphamide, thalidomide, and dexamethasone (CTD) as initial therapy for patients with multiple myeloma unsuitable for autologous transplantation
- (2011) G. J. Morgan et al. BLOOD
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- (2011) S. Gardam et al. BLOOD
- SMAC Mimetic BV6 Induces Cell Death in Monocytes and Maturation of Monocyte-Derived Dendritic Cells
- (2011) Nicole Müller-Sienerth et al. PLoS One
- Eradication of solid tumors using histone deacetylase inhibitors combined with immune-stimulating antibodies
- (2011) A. J. Christiansen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans
- (2011) G. L. Beatty et al. SCIENCE
- Inflammation driven by tumour-specific Th1 cells protects against B-cell cancer
- (2011) Ole Audun Werner Haabeth et al. Nature Communications
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- (2011) Janelle C. Waite et al. PLoS Pathogens
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- Smac mimetics: implications for enhancement of targeted therapies in leukemia
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- CD4+ T cell regulation of CD25 expression controls development of short-lived effector CD8+ T cells in primary and secondary responses
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