USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation

Primary Immunodeficiencies and Inflammatory Disease: A Growing Genetic Intersection

(2016) Nassima Fodil et al.   TRENDS IN IMMUNOLOGY

Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms

(2015) Huan Zhang et al.   Scientific Reports

USP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination

(2015) Prasanna Vasudevan Iyengar et al.   Scientific Reports

The deubiquitinase USP15 antagonizes Parkin-mediated mitochondrial ubiquitination and mitophagy

(2014) Tom Cornelissen et al.   HUMAN MOLECULAR GENETICS

THEMIS Is Required for Pathogenesis of Cerebral Malaria and Protection against Pulmonary Tuberculosis

(2014) Sabrina Torre et al.   INFECTION AND IMMUNITY

The U4/U6 Recycling Factor SART3 Has Histone Chaperone Activity and Associates with USP15 to Regulate H2B Deubiquitination

(2014) Lindsey Long et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation

(2014) James M. Kennedy et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Loss of Suppressor of Cytokine Signaling 1 in Helper T Cells Leads to Defective Th17 Differentiation by Enhancing Antagonistic Effects of IFN-  on STAT3 and Smads

(2014) K. Tanaka et al.   JOURNAL OF IMMUNOLOGY

USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses

(2014) Qiang Zou et al.   NATURE IMMUNOLOGY

The Ubiquitin-Specific Protease USP15 Promotes RIG-I-Mediated Antiviral Signaling by Deubiquitylating TRIM25

(2014) E.-K. Pauli et al.   Science Signaling

Interferon-Mediated Innate Immune Responses against Malaria Parasite Liver Stages

(2014) Jessica L. Miller et al.   Cell Reports

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Type I interferons contribute to experimental cerebral malaria development in response to sporozoite or blood-stagePlasmodium bergheiANKA

(2013) Jennifer Palomo et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Susceptibility to lethal cerebral malaria is regulated by epistatic interaction between chromosome 4 (Berr6) and chromosome 1 (Berr7) loci in mice

(2013) S Torre et al.   GENES AND IMMUNITY

Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria

(2013) Hani Kim et al.   INFECTION AND IMMUNITY

IFNAR1 Controls Progression to Cerebral Malaria in Children and CD8+ T Cell Brain Pathology in Plasmodium berghei-Infected Mice

(2013) E. A. Ball et al.   JOURNAL OF IMMUNOLOGY

USP15 Negatively Regulates Nrf2 through Deubiquitination of Keap1

(2013) Nicole F. Villeneuve et al.   MOLECULAR CELL

Genetics of rheumatoid arthritis contributes to biology and drug discovery

(2013) Yukinori Okada et al.   NATURE

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Host-cell sensors for Plasmodium activate innate immunity against liver-stage infection

(2013) Peter Liehl et al.   NATURE MEDICINE

Inflammatory Responses Associated with the Induction of Cerebral Malaria: Lessons from Experimental Murine Models

(2013) Diana S. Hansen   PLoS Pathogens

Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria

(2013) Joanne Berghout et al.   PLoS Pathogens

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration

(2012) H. Thorvaldsdottir et al.   BRIEFINGS IN BIOINFORMATICS

Comparison of polarization properties of human adult microglia and blood-derived macrophages

(2012) Bryce A. Durafourt et al.   GLIA

Genome-wide association study of lung function decline in adults with and without asthma

(2012) Medea Imboden et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Direct and Indirect Control of Mitogen-activated Protein Kinase Pathway-associated Components, BRAP/IMP E3 Ubiquitin Ligase and CRAF/RAF1 Kinase, by the Deubiquitylating Enzyme USP15

(2012) Sebastian D. Hayes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

USP15 stabilizes TGF-β receptor I and promotes oncogenesis through the activation of TGF-β signaling in glioblastoma

(2012) Pieter J A Eichhorn et al.   NATURE MEDICINE

INTERFEROME v2.0: an updated database of annotated interferon-regulated genes

(2012) Irina Rusinova et al.   NUCLEIC ACIDS RESEARCH

An N-Ethyl-N-Nitrosourea (ENU)-Induced Dominant Negative Mutation in the JAK3 Kinase Protects against Cerebral Malaria

(2012) Silayuv E. Bongfen et al.   PLoS One

Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome

(2011) Shruti Sharma et al.   IMMUNITY

Linear Ubiquitin Assembly Complex Negatively Regulates RIG-I- and TRIM25-Mediated Type I Interferon Induction

(2011) Kyung-Soo Inn et al.   MOLECULAR CELL

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

USP15 is a deubiquitylating enzyme for receptor-activated SMADs

(2011) Masafumi Inui et al.   NATURE CELL BIOLOGY

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

(2011) Deborah S. Cunninghame Graham et al.   PLoS Genetics

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Host resistance to malaria: using mouse models to explore the host response

(2010) Rhea Longley et al.   MAMMALIAN GENOME

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

A scaling normalization method for differential expression analysis of RNA-seq data

(2010) Mark D Robinson et al.   GENOME BIOLOGY

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY