THEMIS Is Required for Pathogenesis of Cerebral Malaria and Protection against Pulmonary Tuberculosis

Differential Function of Themis CABIT Domains during T Cell Development

(2014) Toshiyuki Okada et al.   PLoS One

THEMIS and PTPRK in celiac intestinal mucosa: coexpression in disease and after in vitro gliadin challenge

(2013) Constanza Bondar et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Susceptibility to lethal cerebral malaria is regulated by epistatic interaction between chromosome 4 (Berr6) and chromosome 1 (Berr7) loci in mice

(2013) S Torre et al.   GENES AND IMMUNITY

Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria

(2013) Hani Kim et al.   INFECTION AND IMMUNITY

GRB2-Mediated Recruitment of THEMIS to LAT Is Essential for Thymocyte Development

(2013) W. Paster et al.   JOURNAL OF IMMUNOLOGY

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

(2013) Ashley H Beecham et al.   NATURE GENETICS

Inflammatory Responses Associated with the Induction of Cerebral Malaria: Lessons from Experimental Murine Models

(2013) Diana S. Hansen   PLoS Pathogens

Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria

(2013) Joanne Berghout et al.   PLoS Pathogens

Interchangeability of Themis1 and Themis2 in Thymocyte Development Reveals Two Related Proteins with Conserved Molecular Function

(2012) R. Lesourne et al.   JOURNAL OF IMMUNOLOGY

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

Tespa1 is involved in late thymocyte development through the regulation of TCR-mediated signaling

(2012) Di Wang et al.   NATURE IMMUNOLOGY

An N-Ethyl-N-Nitrosourea (ENU)-Induced Dominant Negative Mutation in the JAK3 Kinase Protects against Cerebral Malaria

(2012) Silayuv E. Bongfen et al.   PLoS One

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease

(2011) Gosia Trynka et al.   NATURE GENETICS

Isolation of Brain and Spinal Cord Mononuclear Cells Using Percoll Gradients

(2011) Paula A. Pino et al.   Jove-Journal of Visualized Experiments

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Bulk Segregation Mapping of Mutations in Closely Related Strains of Mice

(2010) Y. Xia et al.   GENETICS

T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

(2010) Claudia Brockmeyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host resistance to malaria: using mouse models to explore the host response

(2010) Rhea Longley et al.   MAMMALIAN GENOME

Multiple common variants for celiac disease influencing immune gene expression

(2010) Patrick C A Dubois et al.   NATURE GENETICS

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

Grb2 functions at the top of the T-cell antigen receptor-induced tyrosine kinase cascade to control thymic selection

(2010) I. K. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A Novel Gene Essential for the Development of Single Positive Thymocytes

(2009) K. Kakugawa et al.   MOLECULAR AND CELLULAR BIOLOGY

Themis, a T cell–specific protein important for late thymocyte development

(2009) Renaud Lesourne et al.   NATURE IMMUNOLOGY

Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection

(2009) Andy L Johnson et al.   NATURE IMMUNOLOGY

Themis imposes new law and order on positive selection

(2009) Paul M Allen   NATURE IMMUNOLOGY

Themis controls thymocyte selection through regulation of T cell antigen receptor–mediated signaling

(2009) Guo Fu et al.   NATURE IMMUNOLOGY

Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes

(2009) M. S. Patrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T cell immunodeficiency

(2008) J D M Edgar   JOURNAL OF CLINICAL PATHOLOGY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Common variants at CD40 and other loci confer risk of rheumatoid arthritis

(2008) Soumya Raychaudhuri et al.   NATURE GENETICS