Irf8-Regulated Genomic Responses Drive Pathological Inflammation during Cerebral Malaria

Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

(2012) Luke Jostins et al.   NATURE

An N-Ethyl-N-Nitrosourea (ENU)-Induced Dominant Negative Mutation in the JAK3 Kinase Protects against Cerebral Malaria

(2012) Silayuv E. Bongfen et al.   PLoS One

Dissecting the Genetics of Complex Inheritance: Linkage Disequilibrium Mapping Provides Insight into Crohn Disease

(2011) Heather Elding et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Neuropathology of Fatal Cerebral Malaria in Malawian Children

(2011) Katerina Dorovini-Zis et al.   AMERICAN JOURNAL OF PATHOLOGY

Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes

(2011) Lihua Shi et al.   GENE

Prevention of Experimental Cerebral Malaria by Flt3 Ligand during Infection with Plasmodium berghei ANKA

(2011) Takahiko Tamura et al.   INFECTION AND IMMUNITY

Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria

(2011) Adeline Porcherie et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: IRF8 Regulates Bax Transcription In Vivo in Primary Myeloid Cells

(2011) J. Yang et al.   JOURNAL OF IMMUNOLOGY

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis

(2011) Stephen Sawcer et al.   NATURE

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

IRF8Mutations and Human Dendritic-Cell Immunodeficiency

(2011) Sophie Hambleton et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD8+ T Cells and IFN-γ Mediate the Time-Dependent Accumulation of Infected Red Blood Cells in Deep Organs during Experimental Cerebral Malaria

(2011) Carla Claser et al.   PLoS One

The Genetic Association of Variants in CD6, TNFRSF1A and IRF8 to Multiple Sclerosis: A Multicenter Case-Control Study

(2011)   PLoS One

IRF8 Governs Expression of Genes Involved in Innate and Adaptive Immunity in Human and Mouse Germinal Center B Cells

(2011) Dong-Mi Shin et al.   PLoS One

Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation

(2011) Xinshou Ouyang et al.   Nature Communications

Interferon Regulatory Factor 8 Regulates Pathways for Antigen Presentation in Myeloid Cells and during Tuberculosis

(2011) Jean-François Marquis et al.   PLoS Genetics

Association of NCF2, IKZF1, IRF8, IFIH1, and TYK2 with Systemic Lupus Erythematosus

(2011) Deborah S. Cunninghame Graham et al.   PLoS Genetics

IFN Regulatory Factor 8 Restricts the Size of the Marginal Zone and Follicular B Cell Pools

(2010) J. Feng et al.   JOURNAL OF IMMUNOLOGY

Host resistance to malaria: using mouse models to explore the host response

(2010) Rhea Longley et al.   MAMMALIAN GENOME

A Pituitary-Specific Enhancer of the POMC Gene with Preferential Activity in Corticotrope Cells

(2010) David Langlais et al.   MOLECULAR ENDOCRINOLOGY

Identification of a novel cerebral malaria susceptibility locus (Berr5) on mouse chromosome 19

(2009) J Berghout et al.   GENES AND IMMUNITY

Restriction of Legionella pneumophila Replication in Macrophages Requires Concerted Action of the Transcriptional Regulators Irf1 and Irf8 and Nod-Like Receptors Naip5 and Nlrc4

(2009) A. Fortier et al.   INFECTION AND IMMUNITY

Disseminated and Rapidly Fatal Tuberculosis in Mice Bearing a Defective Allele at IFN Regulatory Factor 8

(2009) J.-F. Marquis et al.   JOURNAL OF IMMUNOLOGY

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci

(2009) Philip L De Jager et al.   NATURE GENETICS

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

The IRF Family Transcription Factors in Immunity and Oncogenesis

(2008) Tomohiko Tamura et al.   Annual Review of Immunology

lumi: a pipeline for processing Illumina microarray

(2008) P. Du et al.   BIOINFORMATICS

IRF8 regulates B-cell lineage specification, commitment, and differentiation

(2008) H. Wang et al.   BLOOD

IRF8 regulates myeloid and B lymphoid lineage diversification

(2008) Hongsheng Wang et al.   IMMUNOLOGIC RESEARCH

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Blood-stage Plasmodium infection induces CD8+ T lymphocytes to parasite-expressed antigens, largely regulated by CD8 + dendritic cells

(2008) R. J. Lundie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemokine receptor CXCR3 and its ligands CXCL9 and CXCL10 are required for the development of murine cerebral malaria

(2008) G. S. V. Campanella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY