Hdac1 and Hdac2 positively regulate Notch1 gain‐of‐function pathogenic signaling in committed osteoblasts of male mice

Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

(2021) Chen-Yi Tang et al.   PLoS Genetics

Selective Targeting of Class I Histone Deacetylases in a Model of Human Osteosarcoma

(2021) Haydee M. Torres et al.   Cancers

HDAC3 functions as a positive regulator in Notch signal transduction

(2020) Francesca Ferrante et al.   NUCLEIC ACIDS RESEARCH

Role of histone deacetylases in bone development and skeletal disorders

(2020) Jialiang S. Wang et al.   BONE

Podocyte histone deacetylase activity regulates murine and human glomerular diseases

(2019) Kazunori Inoue et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone deacetylase 6 controls Notch3 trafficking and degradation in T-cell acute lymphoblastic leukemia cells

(2018) Marica Pinazza et al.   ONCOGENE

The histone deacetylase HDAC1 positively regulates Notch signaling during Drosophila wing development

(2018) Zehua Wang et al.   Biology Open

Histone Deacetylases in Bone Development and Skeletal Disorders

(2015) Elizabeth W. Bradley et al.   PHYSIOLOGICAL REVIEWS

Mutations in NOTCH1 Cause Adams-Oliver Syndrome

(2014) Anna-Barbara Stittrich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Notch Activation as a Driver of Osteogenic Sarcoma

(2014) Jianning Tao et al.   CANCER CELL

NOTCH1-RBPJ complexes drive target gene expression through dynamic interactions with superenhancers

(2013) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NOTCH1 Nuclear Interactome Reveals Key Regulators of Its Transcriptional Activity and Oncogenic Function

(2012) Ahmad Yatim et al.   MOLECULAR CELL

Histone Deacetylase Activity Selectively Regulates Notch‐Mediated Smooth Muscle Differentiation in Human Vascular Cells

(2012) Yuefeng Tang et al.   Journal of the American Heart Association

Suberoylanilide hydroxamic acid (SAHA; vorinostat) causes bone loss by inhibiting immature osteoblasts

(2011) Meghan E. McGee-Lawrence et al.   BONE

Acetylation controls Notch3 stability and function in T-cell leukemia

(2011) R Palermo et al.   ONCOGENE

Alteration of Notch signaling in skeletal development and disease

(2010) Jianning Tao et al.   Annals of the New York Academy of Sciences

Distinct roles of GCN5/PCAF-mediated H3K9ac and CBP/p300-mediated H3K18/27ac in nuclear receptor transactivation

(2010) Qihuang Jin et al.   EMBO JOURNAL

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

(2010) T. Yamaguchi et al.   GENES & DEVELOPMENT

Osteosclerosis owing to Notch gain of function is solely Rbpj-dependent

(2010) Jianning Tao et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Notch Inhibits Osteoblast Differentiation and Causes Osteopenia

(2008) Stefano Zanotti et al.   ENDOCRINOLOGY

Dimorphic effects of Notch signaling in bone homeostasis

(2008) Feyza Engin et al.   NATURE MEDICINE

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE