Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

Runx1 up-regulates chondrocyte to osteoblast lineage commitment and promotes bone formation by enhancing both chondrogenesis and osteogenesis

(2020) Chenyi Tang et al.   BIOCHEMICAL JOURNAL

Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation

(2019) Yujiao Han et al.   JOURNAL OF CLINICAL INVESTIGATION

Cbfβ governs osteoblast−adipocyte lineage commitment through enhancing β-catenin signaling and suppressing adipogenesis gene expression

(2017) Mengrui Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gα13 negatively controls osteoclastogenesis through inhibition of the Akt-GSK3β-NFATc1 signalling pathway

(2017) Mengrui Wu et al.   Nature Communications

Matters of context guide future research in TGFβ superfamily signaling

(2015) Rosemary J. Akhurst et al.   Science Signaling

Matters of context guide future research in TGFβ superfamily signaling

(2015) Rosemary J. Akhurst et al.   Science Signaling

Deletion of core-binding factor β (Cbfβ) in mesenchymal progenitor cells provides new insights into Cbfβ/Runxs complex function in cartilage and bone development

(2014) Mengrui Wu et al.   BONE

Chondrocyte-specific Knockout of Cbfβ Reveals the Indispensable Function of Cbfβ in Chondrocyte Maturation, Growth Plate Development and Trabecular Bone Formation in Mice

(2014) Mengrui Wu et al.   International Journal of Biological Sciences

Core Binding Factor Beta (Cbfβ) Controls the Balance of Chondrocyte Proliferation and Differentiation by Upregulating Indian hedgehog (Ihh) Expression and Inhibiting Parathyroid Hormone-Related Protein Receptor (PPR) Expression in Postnatal Cartilage and

(2014) Fei Tian et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Cbf  deletion in mice recapitulates cleidocranial dysplasia and reveals multiple functions of Cbf  required for skeletal development

(2014) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Runx1 Is Critical for PTH-induced Onset of Mesenchymal Progenitor Cell Chondrogenic Differentiation

(2013) Jinwu Wang et al.   PLoS One

Signaling Networks that Control the Lineage Commitment and Differentiation of Bone Cells

(2012) Carrie S. Soltanoff et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

TGF-β and BMP Signaling in Osteoblast Differentiation and Bone Formation

(2012) Guiqian Chen et al.   International Journal of Biological Sciences

Runx1 dose-dependently regulates endochondral ossification during skeletal development and fracture healing

(2012) Do Y Soung et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Runx1 and Runx2 cooperate during sternal morphogenesis

(2010) A. Kimura et al.   DEVELOPMENT

Transcriptional Regulation of Osteoblasts

(2008) Renny T. Franceschi et al.   CELLS TISSUES ORGANS

Adipocyte differentiation of bone marrow-derived mesenchymal stem cells: Cross talk with the osteoblastogenic program

(2008) S. Muruganandan et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Bone and fat connection in aging bone

(2008) Gustavo Duque   CURRENT OPINION IN RHEUMATOLOGY

The effect of thiazolidinediones on BMD and osteoporosis

(2008) Allyson K McDonough et al.   Nature clinical practice. Endocrinology & metabolism