Podocyte histone deacetylase activity regulates murine and human glomerular diseases

Stabilization of NF-κB-Inducing Kinase Suppresses MLL-AF9-Induced Acute Myeloid Leukemia

(2018) Yan Xiu et al.   Cell Reports

Sodium Butyrate Protects ­Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice

(2017) Ling Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pharmacological agents to reduce readmissions in bipolar disorder

(2017) Jonathan Rogers et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Inhibiting Histone Deacetylase 2 (HDAC2) Promotes Functional Recovery From Stroke

(2017) Ying Tang et al.   Journal of the American Heart Association

Egr-1 deficiency protects from renal inflammation and fibrosis

(2016) Li-Chun Ho et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

A novel histone deacetylase 1 and 2 isoform-specific inhibitor alleviates experimental Parkinson's disease

(2016) Chi-Jing Choong et al.   NEUROBIOLOGY OF AGING

Sublytic C5b-9 triggers glomerular mesangial cell apoptosis in rat Thy-1 nephritis via Gadd45 activation mediated by Egr-1 and p300-dependent ATF3 acetylation

(2016) Fengxia He et al.   Journal of Molecular Cell Biology

Toward dissecting the etiology of schizophrenia: HDAC1 and DAXX regulate GAD67 expression in an in vitro hippocampal GABA neuron model

(2016) S Subburaju et al.   Translational Psychiatry

The cell biology of renal filtration

(2015) Rizaldy P. Scott et al.   JOURNAL OF CELL BIOLOGY

Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes

(2015) H. Hassan et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Longitudinal Study of the Decline in Renal Function in Healthy Subjects

(2015) Mika Baba et al.   PLoS One

γCaMKII Shuttles Ca2+/CaM to the Nucleus to Trigger CREB Phosphorylation and Gene Expression

(2014) Huan Ma et al.   CELL

Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance

(2014) Xuefei Tian et al.   JOURNAL OF CLINICAL INVESTIGATION

Histone deacetylase 4 selectively contributes to podocyte injury in diabetic nephropathy

(2014) Xiaojie Wang et al.   KIDNEY INTERNATIONAL

A New Equation to Estimate Glomerular Filtration Rate

(2013) Andrew S. Levey et al.   ANNALS OF INTERNAL MEDICINE

Histone Deacetylase Inhibitor Enhances Recovery after AKI

(2013) C. Cianciolo Cosentino et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renoprotective Effect of Combined Inhibition of Angiotensin-Converting Enzyme and Histone Deacetylase

(2013) Y. Zhong et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

The Terminator mouse is a diphtheria toxin–receptor knock-in mouse strain for rapid and efficient enrichment of desired cell lineages

(2013) Jian-Kan Guo et al.   KIDNEY INTERNATIONAL

Evolving importance of kidney disease: from subspecialty to global health burden

(2013) Kai-Uwe Eckardt et al.   LANCET

Renal albumin filtration: alternative models to the standard physical barriers

(2013) Marcus J. Moeller et al.   Nature Reviews Nephrology

Genome-wide approaches reveal EGR1-controlled regulatory networks associated with neurodegeneration

(2013) Radosveta Koldamova et al.   NEUROBIOLOGY OF DISEASE

Blocking the Class I Histone Deacetylase Ameliorates Renal Fibrosis and Inhibits Renal Fibroblast Activation via Modulating TGF-Beta and EGFR Signaling

(2013) Na Liu et al.   PLoS One

Role of dynamin, synaptojanin, and endophilin in podocyte foot processes

(2012) Keita Soda et al.   JOURNAL OF CLINICAL INVESTIGATION

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Sirtuins as regulators of metabolism and healthspan

(2012) Riekelt H. Houtkooper et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Expression2Kinases: mRNA profiling linked to multiple upstream regulatory layers

(2011) Edward Y. Chen et al.   BIOINFORMATICS

Anti-invasive activity of histone deacetylase inhibitors via the induction of Egr-1 and the modulation of tight junction-related proteins in human hepatocarcinoma cells

(2011) Sung-Ok Kim et al.   BMB Reports

CREB Is a Novel Nuclear Target of PTEN Phosphatase

(2011) T. Gu et al.   CANCER RESEARCH

EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF

(2011) Gabi Tarcic et al.   FASEB JOURNAL

Egr-1 Transactivates Bim Gene Expression to Promote Neuronal Apoptosis

(2011) B. Xie et al.   JOURNAL OF NEUROSCIENCE

Valproic Acid Attenuates Proteinuria and Kidney Injury

(2011) K. Van Beneden et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Induction of Podocyte VEGF164 Overexpression at Different Stages of Development Causes Congenital Nephrosis or Steroid-Resistant Nephrotic Syndrome

(2010) Delma Veron et al.   AMERICAN JOURNAL OF PATHOLOGY

The transcription factor EGR1 regulates metastatic potential of v-src transformed sarcoma cells

(2010) Vladimír Čermák et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Factor binding and chromatin modification in the promoter of murine Egr1 gene upon induction

(2010) Gema Tur et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Histone deacetylases 1 and 2 act in concert to promote the G1-to-S progression

(2010) T. Yamaguchi et al.   GENES & DEVELOPMENT

Inhibition of Podocyte FAK Protects against Proteinuria and Foot Process Effacement

(2010) H. Ma et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

EGR1 reactivation by histone deacetylase inhibitors promotes synovial sarcoma cell death through the PTEN tumor suppressor

(2010) L Su et al.   ONCOGENE

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL

Blood pressure in chronic kidney disease stage 5D—report from a Kidney Disease: Improving Global Outcomes controversies conference

(2009) Nathan W. Levin et al.   KIDNEY INTERNATIONAL

Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development

(2009) R. L. Montgomery et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Valproic acid as epigenetic cancer drug: Preclinical, clinical and transcriptional effects on solid tumors

(2008) Alfonso Duenas-Gonzalez et al.   CANCER TREATMENT REVIEWS

Oxygen Deprivation Triggers Upregulation of Early Growth Response-1 by the Receptor for Advanced Glycation End Products

(2008) Jong Sun Chang et al.   CIRCULATION RESEARCH

The many roles of histone deacetylases in development and physiology: implications for disease and therapy

(2008) Michael Haberland et al.   NATURE REVIEWS GENETICS