Biomimetic “gemini nanoimmunoregulators” orchestrated for boosted photoimmunotherapy by spatiotemporally modulating PD-L1 and tumor-associated macrophages

Thermal immuno-nanomedicine in cancer

(2023) Zhe Yang et al.   Nature Reviews Clinical Oncology

Emerging vaccine nanotechnology: From defense against infection to sniping cancer

(2022) Chan Feng et al.   Acta Pharmaceutica Sinica B

Nanotechnology-based multifunctional vaccines for cancer immunotherapy

(2022) Xiaoxue Xie et al.   CHEMICAL ENGINEERING JOURNAL

Reversing tumor to “Hot”: A NIR light-triggered carrier-free nanoplatform for enhanced tumor penetration and photo-induced immunotherapy

(2022) Shuo Wang et al.   CHEMICAL ENGINEERING JOURNAL

Potential solutions for manufacture of CAR T cells in cancer immunotherapy

(2022) Ulrich Blache et al.   Nature Communications

Small molecule-based immunomodulators for cancer therapy

(2022) Yinrong Wu et al.   Acta Pharmaceutica Sinica B

Boosting anti-PD-1 therapy with metformin-loaded macrophage-derived microparticles

(2021) Zhaohan Wei et al.   Nature Communications

Metformin Liposome-Mediated PD-L1 Downregulation for Amplifying the Photodynamic Immunotherapy Efficacy

(2021) Wei Xiong et al.   ACS Applied Materials & Interfaces

Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice

(2021) Julia Wagner et al.   ACS Nano

Activatable polymer nanoagonist for second near-infrared photothermal immunotherapy of cancer

(2021) Yuyan Jiang et al.   Nature Communications

Polarization of Tumor-Associated Macrophages by Nanoparticle-Loaded Escherichia coli Combined with Immunogenic Cell Death for Cancer Immunotherapy

(2021) Baicheng Wei et al.   NANO LETTERS

IL-6 signaling in macrophages is required for immunotherapy-driven regression of tumors

(2021) Elham Beyranvand Nejad et al.   Journal for ImmunoTherapy of Cancer

An Integrated Nanoaircraft Carrier Modulating Antitumor Immunity to Enhance Immune Checkpoint Blockade Therapy

(2021) Shuang Liang et al.   ADVANCED FUNCTIONAL MATERIALS

Symphony of nanomaterials and immunotherapy based on the cancer‒immunity cycle

(2021) Qianqian Li et al.   Acta Pharmaceutica Sinica B

Bortezomib-Encapsulated CuS/Carbon Dots Nanocomposites for Enhanced Photothermal Therapy via Stabilization of Polyubiquitinated Substrates in the Proteasomal Degradation Pathway

(2020) Ying Yu et al.   ACS Nano

Site-specific MOF-based immunotherapeutic nanoplatforms via synergistic tumor cells-targeted treatment and dendritic cells-targeted immunomodulation

(2020) Huiyuan Zhang et al.   BIOMATERIALS

Injectable Liquid Crystal Formation System for Reshaping Tumor Immunosuppressive Microenvironment to Boost Antitumor Immunity: Postoperative Chemoimmunotherapy

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Metabolic rewiring of macrophages by CpG potentiates clearance of cancer cells and overcomes tumor-expressed CD47−mediated ‘don’t-eat-me’ signal

(2019) Mingen Liu et al.   NATURE IMMUNOLOGY

Metformin inhibits metastatic breast cancer progression and improves chemosensitivity by inducing vessel normalization via PDGF-B downregulation

(2019) Ji-Chang Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine

(2019) Wei Cheng et al.   ACS Nano

Lyophilizable and Multifaceted Toll-like Receptor 7/8 Agonist-Loaded Nanoemulsion for the Reprogramming of Tumor Microenvironments and Enhanced Cancer Immunotherapy

(2019) Sun-Young Kim et al.   ACS Nano

Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

(2019) Liping Huang et al.   Nature Communications

Iron chelated melanin-like nanoparticles for tumor-associated macrophage repolarization and cancer therapy

(2019) Lei Rong et al.   BIOMATERIALS

Understanding the tumor immune microenvironment (TIME) for effective therapy

(2018) Mikhail Binnewies et al.   NATURE MEDICINE

TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy

(2018) Christopher B. Rodell et al.   Nature Biomedical Engineering

Recent advances in applying nanotechnologies for cancer immunotherapy

(2018) Reza Mahjub et al.   JOURNAL OF CONTROLLED RELEASE

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

(2018) Jong-Ho Cha et al.   MOLECULAR CELL

Targeting cancer-related inflammation in the era of immunotherapy

(2017) Kyohei Nakamura et al.   IMMUNOLOGY AND CELL BIOLOGY

Tumour-associated macrophages as treatment targets in oncology

(2017) Alberto Mantovani et al.   Nature Reviews Clinical Oncology

Economic sustainability of anti-PD-1 agents nivolumab and pembrolizumab in cancer patients: Recent insights and future challenges

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Safety profiles of anti-CTLA-4 and anti-PD-1 antibodies alone and in combination

(2016) Celine Boutros et al.   Nature Reviews Clinical Oncology

Immune Escape Mechanisms as a Guide for Cancer Immunotherapy

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Targeted delivery of proapoptotic peptides to tumor-associated macrophages improves survival

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Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Cancer immunotherapy comes of age

(2011) Ira Mellman et al.   NATURE

Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils

(2011) Stephen J Galli et al.   NATURE IMMUNOLOGY