Mild photothermal therapy potentiates anti-PD-L1 treatment for immunologically cold tumors via an all-in-one and all-in-control strategy

Approaches to treat immune hot, altered and cold tumours with combination immunotherapies

(2019) Jérôme Galon et al.   NATURE REVIEWS DRUG DISCOVERY

Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

(2018) Liangliang Dai et al.   ADVANCED FUNCTIONAL MATERIALS

PD-1 Blockade Cellular Vesicles for Cancer Immunotherapy

(2018) Xudong Zhang et al.   ADVANCED MATERIALS

Injectable Bioresponsive Gel Depot for Enhanced Immune Checkpoint Blockade

(2018) Shuangjiang Yu et al.   ADVANCED MATERIALS

Efficacy of chemotherapy or chemo-anti-PD-1 combination after failed anti-PD-1 therapy for relapsed and refractory Hodgkin lymphoma: A series from Lysa centers

(2018) Cédric Rossi et al.   AMERICAN JOURNAL OF HEMATOLOGY

Mitigation of Inflammatory Immune Responses with Hydrophilic Nanoparticles

(2018) Bowen Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Host expression of PD-L1 determines efficacy of PD-L1 pathway blockade–mediated tumor regression

(2018) Heng Lin et al.   JOURNAL OF CLINICAL INVESTIGATION

Versatile redox-sensitive pullulan nanoparticles for enhanced liver targeting and efficient cancer therapy

(2018) Liping Huang et al.   Nanomedicine-Nanotechnology Biology and Medicine

In situ formed reactive oxygen species–responsive scaffold with gemcitabine and checkpoint inhibitor for combination therapy

(2018) Chao Wang et al.   Science Translational Medicine

Multi-faceted immunomodulatory and tissue-tropic clinical bacterial isolate potentiates prostate cancer immunotherapy

(2018) Jonathan F. Anker et al.   Nature Communications

Delivery Strategies for Immune Checkpoint Blockade

(2018) Qian Chen et al.   Advanced Healthcare Materials

Fever-Inspired Immunotherapy Based on Photothermal CpG Nanotherapeutics: The Critical Role of Mild Heat in Regulating Tumor Microenvironment

(2018) Yan Li et al.   Advanced Science

Photosensitizer Micelles Together with IDO Inhibitor Enhance Cancer Photothermal Therapy and Immunotherapy

(2018) Jinrong Peng et al.   Advanced Science

Increase in PD-L1 expression after pre-operative radiotherapy for soft tissue sarcoma

(2018) Kirtesh R. Patel et al.   OncoImmunology

Combined local immunostimulatory radioisotope therapy and systemic immune checkpoint blockade imparts potent antitumour responses

(2018) Yu Chao et al.   Nature Biomedical Engineering

Toward Biomaterials for Enhancing Immune Checkpoint Blockade Therapy

(2018) Qin Fan et al.   ADVANCED FUNCTIONAL MATERIALS

Recent advances in applying nanotechnologies for cancer immunotherapy

(2018) Reza Mahjub et al.   JOURNAL OF CONTROLLED RELEASE

A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization

(2018) Miguel F. Sanmamed et al.   CELL

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers

(2018) Wouter Scheper et al.   NATURE MEDICINE

Efficient Near Infrared Light Triggered Nitric Oxide Release Nanocomposites for Sensitizing Mild Photothermal Therapy

(2018) Xiao Zhang et al.   Advanced Science

Tumour and host cell PD-L1 is required to mediate suppression of anti-tumour immunity in mice

(2017) Janet Lau et al.   Nature Communications

Genomic Analysis of Tumor Microenvironment Immune Types across 14 Solid Cancer Types: Immunotherapeutic Implications

(2017) Yu-Pei Chen et al.   Theranostics

Synergistic Immuno Photothermal Nanotherapy (SYMPHONY) for the Treatment of Unresectable and Metastatic Cancers

(2017) Yang Liu et al.   Scientific Reports

Enhanced Cancer Immunotherapy by Microneedle Patch-Assisted Delivery of Anti-PD1 Antibody

(2016) Chao Wang et al.   NANO LETTERS

PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations

(2016) Weiping Zou et al.   Science Translational Medicine

Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy

(2016) Qian Chen et al.   Nature Communications

Comparative Analysis of Protocols to Induce Human CD4+Foxp3+ Regulatory T Cells by Combinations of IL-2, TGF-beta, Retinoic Acid, Rapamycin and Butyrate

(2016) Angelika Schmidt et al.   PLoS One

Supramolecular peptide vaccines: tuning adaptive immunity

(2015) Yi Wen et al.   CURRENT OPINION IN IMMUNOLOGY

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

(2015) Stefani Spranger et al.   NATURE

Virus-mimetic nanovesicles as a versatile antigen-delivery system

(2015) Pengfei Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic antitumor immunity by checkpoint blockade is enhanced by ibrutinib, an inhibitor of both BTK and ITK

(2015) Idit Sagiv-Barfi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Formation of Highly Structured Cubic Micellar Lipid Nanoparticles of Soy Phosphatidylcholine and Glycerol Dioleate and Their Degradation by Triacylglycerol Lipase

(2014) Maria Wadsäter et al.   ACS Applied Materials & Interfaces

Immunological Responses Triggered by Photothermal Therapy with Carbon Nanotubes in Combination with Anti-CTLA-4 Therapy to Inhibit Cancer Metastasis

(2014) Chao Wang et al.   ADVANCED MATERIALS

Synergistic effects of IL-4 and TNFα on the induction of B7-H1 in renal cell carcinoma cells inhibiting allogeneic T cell proliferation

(2014) Dagmar Quandt et al.   Journal of Translational Medicine

PD-1 blockade induces responses by inhibiting adaptive immune resistance

(2014) Paul C. Tumeh et al.   NATURE

Recent In Vivo Evidences of Particle-Based Delivery of Small-Interfering RNA (siRNA) into Solid Tumors

(2014) Yi Wen et al.   Journal of Pharmaceutical Innovation

Increased plasticity of the stiffness of melanoma cells correlates with their acquisition of metastatic properties

(2013) Gilles Weder et al.   Nanomedicine-Nanotechnology Biology and Medicine

IgA plasma cells express the negative regulatory co-stimulatory molecule programmed cell death 1 ligand and have a potential tolerogenic role in the intestine

(2012) Tomomitsu Doi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Antitumor immunologically modified carbon nanotubes for photothermal therapy

(2012) Feifan Zhou et al.   BIOMATERIALS

A Requisite Role for Induced Regulatory T Cells in Tolerance Based on Expanding Antigen Receptor Diversity

(2011) Dipica Haribhai et al.   IMMUNITY

Enhancing immune responses to tumor-associated antigens

(2010) Jack P. Higgins et al.   CANCER BIOLOGY & THERAPY