A survey of the specificity and mechanism of 1,6 hexanediol-induced disruption of nuclear transport

Visualizing the disordered nuclear transport machinery in situ

(2023) Miao Yu et al.   NATURE

Self-regulation of the nuclear pore complex enables clogging-free crowded transport

(2023) Tiantian Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Karyopherin enrichment and compensation fortifies the nuclear pore complex against nucleocytoplasmic leakage

(2022) Joanna Kalita et al.   JOURNAL OF CELL BIOLOGY

Super-resolved 3D tracking of cargo transport through nuclear pore complexes

(2022) Rajdeep Chowdhury et al.   NATURE CELL BIOLOGY

Karyopherin-mediated nucleocytoplasmic transport

(2022) Casey E. Wing et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Crowding-induced phase separation of nuclear transport receptors in FG nucleoporin assemblies

(2022) Luke K Davis et al.   eLife

Hsp104 N‐terminal domain interaction with substrates plays a regulatory role in protein disaggregation

(2022) Anna Harari et al.   FEBS Journal

F/YGG-motif is an intrinsically disordered nucleic-acid binding motif

(2022) Joris Van Lindt et al.   RNA Biology

The Nuclear Pore Complex: Birth, Life, and Death of a Cellular Behemoth

(2022) Elisa Dultz et al.   Cells

Transport receptor occupancy in nuclear pore complex mimics

(2022) Alessio Fragasso et al.   Nano Research

The chaperone DNAJB6 surveils FG-nucleoporins and is required for interphase nuclear pore complex biogenesis

(2022) E. F. Elsiena Kuiper et al.   NATURE CELL BIOLOGY

Direct binding of ESCRT protein Chm7 to phosphatidic acid–rich membranes at nuclear envelope herniations

(2021) David J. Thaller et al.   JOURNAL OF CELL BIOLOGY

Cargo transport through the nuclear pore complex at a glance

(2021) Giulia Paci et al.   JOURNAL OF CELL SCIENCE

One Ring to Rule them All? Structural and Functional Diversity in the Nuclear Pore Complex

(2021) Javier Fernandez-Martinez et al.   TRENDS IN BIOCHEMICAL SCIENCES

On the asymmetric partitioning of nucleocytoplasmic transport – recent insights and open questions

(2021) Joanna Kalita et al.   JOURNAL OF CELL SCIENCE

Physics of the nuclear pore complex: Theory, modeling and experiment

(2021) Bart W. Hoogenboom et al.   PHYSICS REPORTS-REVIEW SECTION OF PHYSICS LETTERS

Karyopherins and condensates

(2020) Charis E. Springhower et al.   CURRENT OPINION IN CELL BIOLOGY

Modeling the nucleoporins that form the hairy pores

(2020) Kai Huang et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

A physicochemical perspective of aging from single-cell analysis of pH, macromolecular and organellar crowding in yeast

(2020) Sara N Mouton et al.   eLife

Structure and Assembly of the Nuclear Pore Complex

(2019) Bernhard Hampoelz et al.   Annual Review of Biophysics

An ESCRT-LEM protein surveillance system is poised to directly monitor the nuclear envelope and nuclear transport system

(2019) David J Thaller et al.   eLife

Age-dependent deterioration of nuclear pore assembly in mitotic cells decreases transport dynamics

(2019) Irina L Rempel et al.   eLife

The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes

(2019) Giorgia Celetti et al.   JOURNAL OF CELL BIOLOGY

A Programmable DNA Origami Platform for Organizing Intrinsically Disordered Nucleoporins within Nanopore Confinement

(2018) Patrick D. Ellis Fisher et al.   ACS Nano

Thermodynamic characterization of the multivalent interactions underlying rapid and selective translocation through the nuclear pore complex

(2018) Ryo Hayama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Deciphering the “Fuzzy” Interaction of FG Nucleoporins and Transport Factors Using Small-Angle Neutron Scattering

(2018) Samuel Sparks et al.   STRUCTURE

Integrative structure and functional anatomy of a nuclear pore complex

(2018) Seung Joong Kim et al.   NATURE

Karyopherins regulate nuclear pore complex barrier and transport function

(2017) Larisa E. Kapinos et al.   JOURNAL OF CELL BIOLOGY

Toxic PRnpoly-dipeptides encoded by theC9orf72repeat expansion block nuclear import and export

(2017) Kevin Y. Shi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxic PR Poly-Dipeptides Encoded by the C9orf72 Repeat Expansion Target LC Domain Polymers

(2016) Yi Lin et al.   CELL

Chm7 and Heh1 collaborate to link nuclear pore complex quality control with nuclear envelope sealing

(2016) Brant M Webster et al.   EMBO JOURNAL

Simple rules for passive diffusion through the nuclear pore complex

(2016) Benjamin L. Timney et al.   JOURNAL OF CELL BIOLOGY

Spatiotemporal dynamics of the nuclear pore complex transport barrier resolved by high-speed atomic force microscopy

(2016) Yusuke Sakiyama et al.   Nature Nanotechnology

Distinct stages in stress granule assembly and disassembly

(2016) Joshua R Wheeler et al.   eLife

Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors

(2015) Sigrid Milles et al.   CELL

Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

(2015) Amandine Molliex et al.   CELL

Size-dependent leak of soluble and membrane proteins through the yeast nuclear pore complex

(2015) Petra Popken et al.   MOLECULAR BIOLOGY OF THE CELL

The molecular mechanism of nuclear transport revealed by atomic-scale measurements

(2015) Loren E Hough et al.   eLife

Importin-β modulates the permeability of the nuclear pore complex in a Ran-dependent manner

(2015) Alan R Lowe et al.   eLife

Nup98 FG domains from diverse species spontaneously phase-separate into particles with nuclear pore-like permselectivity

(2015) Hermann Broder Schmidt et al.   eLife

Karyopherin-Centric Control of Nuclear Pores Based on Molecular Occupancy and Kinetic Analysis of Multivalent Binding with FG Nucleoporins

(2014) Larisa E. Kapinos et al.   BIOPHYSICAL JOURNAL

Probing the Disordered Domain of the Nuclear Pore Complex through Coarse-Grained Molecular Dynamics Simulations

(2014) Ali Ghavami et al.   BIOPHYSICAL JOURNAL

Quantitative Analysis of Membrane Protein Transport Across the Nuclear Pore Complex

(2013) Anne C. Meinema et al.   TRAFFIC

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Single-molecule transport across an individual biomimetic nuclear pore complex

(2011) Stefan W. Kowalczyk et al.   Nature Nanotechnology

Fluorescence Anisotropy Reveals Order and Disorder of Protein Domains in the Nuclear Pore Complex

(2010) Alexa L. Mattheyses et al.   BIOPHYSICAL JOURNAL

Amyloid-like interactions within nucleoporin FG hydrogels

(2010) C. Ader et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of ATP levels inside single living cells with fluorescence resonance energy transfer-based genetically encoded indicators

(2009) H. Imamura et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificial nanopores that mimic the transport selectivity of the nuclear pore complex

(2008) Tijana Jovanovic-Talisman et al.   NATURE