Genetic Liability to Posttraumatic Stress Disorder Symptoms and Its Association With Cardiometabolic and Respiratory Outcomes

Genetically regulated multi-omics study for symptom clusters of posttraumatic stress disorder highlights pleiotropy with hematologic and cardio-metabolic traits

(2022) Gita A. Pathak et al.   MOLECULAR PSYCHIATRY

Polygenic Scores in Psychiatry: On the Road From Discovery to Implementation

(2022) Cathryn M. Lewis et al.   AMERICAN JOURNAL OF PSYCHIATRY

Leveraging Large-Scale Genetics of PTSD and Cardiovascular Disease to Demonstrate Robust Shared Risk and Improve Risk Prediction Accuracy

(2022) Antonia V. Seligowski et al.   AMERICAN JOURNAL OF PSYCHIATRY

Stem cell models for context-specific modeling in psychiatric disorders

(2022) Carina Seah et al.   BIOLOGICAL PSYCHIATRY

Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression

(2022) Carina Seah et al.   NATURE NEUROSCIENCE

Prevalence and Impact of Post-traumatic Stress Disorder in Gastrointestinal Conditions: A Systematic Review

(2021) Heidi Glynn et al.   DIGESTIVE DISEASES AND SCIENCES

Clinical laboratory test-wide association scan of polygenic scores identifies biomarkers of complex disease

(2021) Jessica K. Dennis et al.   Genome Medicine

Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program

(2021) Murray B. Stein et al.   NATURE GENETICS

Co-occurrence of severe PTSD, somatic symptoms and dissociation in a large sample of childhood trauma inpatients: a network analysis

(2021) Leonhard Kratzer et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

New Metabolic, Digestive, and Oxidative Stress-Related Manifestations Associated with Posttraumatic Stress Disorder

(2021) Bianca Augusta Oroian et al.   Oxidative Medicine and Cellular Longevity

Use of the PsycheMERGE Network to Investigate the Association Between Depression Polygenic Scores and White Blood Cell Count

(2021) Julia M. Sealock et al.   JAMA Psychiatry

Enhancing Discovery of Genetic Variants for Posttraumatic Stress Disorder Through Integration of Quantitative Phenotypes and Trauma Exposure Information

(2021) Adam X. Maihofer et al.   BIOLOGICAL PSYCHIATRY

Dissecting the genetic association of C-reactive protein with PTSD, traumatic events, and social support

(2020) Carolina Muniz Carvalho et al.   NEUROPSYCHOPHARMACOLOGY

Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

(2020) Ke Xu et al.   Nature Communications

From Basic Science to Clinical Application of Polygenic Risk Scores

(2020) Naomi R. Wray et al.   JAMA Psychiatry

Characterizing the effect of background selection on the polygenicity of brain-related traits

(2020) Frank R. Wendt et al.   GENOMICS

Polygenic prediction via Bayesian regression and continuous shrinkage priors

(2019) Tian Ge et al.   Nature Communications

Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

(2019) Michael S. Breen et al.   Translational Psychiatry

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

(2019) Caroline M. Nievergelt et al.   Nature Communications

Symptom severity impacts sympathetic dysregulation and inflammation in post-traumatic stress disorder (PTSD)

(2019) Ida T. Fonkoue et al.   BRAIN BEHAVIOR AND IMMUNITY

The impact of an exercise training intervention on cortisol levels and post-traumatic stress disorder in juveniles from an Ugandan refugee settlement: study protocol for a randomized control trial

(2018) Henning Budde et al.   Trials

The MR-Base platform supports systematic causal inference across the human phenome

(2018) Gibran Hemani et al.   eLife

Posttraumatic Stress Disorder and Gastrointestinal Disorders in the Danish Population

(2017) Jaimie L. Gradus et al.   EPIDEMIOLOGY

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

(2017) Stephen Burgess et al.   EPIDEMIOLOGY

Posttraumatic stress disorder in the World Mental Health Surveys

(2017) K. C. Koenen et al.   PSYCHOLOGICAL MEDICINE

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

The regulation of muscle mass by endogenous glucocorticoids

(2015) Theodore P. Braun et al.   Frontiers in Physiology

R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment

(2014) Robert J. Carroll et al.   BIOINFORMATICS

Minireview: Stress-Related Psychiatric Disorders with Low Cortisol Levels: A Metabolic Hypothesis

(2011) Rachel Yehuda et al.   ENDOCRINOLOGY