Differential transcriptional response following glucocorticoid activation in cultured blood immune cells: a novel approach to PTSD biomarker development

Noncoding RNAs: Stress, Glucocorticoids, and Posttraumatic Stress Disorder

(2018) Nikolaos P. Daskalakis et al.   BIOLOGICAL PSYCHIATRY

How to measure glucocorticoid receptor’s sensitivity in patients with stress-related psychiatric disorders

(2018) Carolin Leistner et al.   PSYCHONEUROENDOCRINOLOGY

PTSD Blood Transcriptome Mega-Analysis: Shared Inflammatory Pathways across Biological Sex and Modes of Trauma

(2017) Michael S Breen et al.   NEUROPSYCHOPHARMACOLOGY

variancePartition: interpreting drivers of variation in complex gene expression studies

(2016) Gabriel E. Hoffman et al.   BMC BIOINFORMATICS

Direct GR Binding Sites Potentiate Clusters of TF Binding across the Human Genome

(2016) Christopher M. Vockley et al.   CELL

Dysregulated immune system networks in war veterans with PTSD is an outcome of altered miRNA expression and DNA methylation

(2016) Marpe Bam et al.   Scientific Reports

Dose-dependent effects of dexamethasone on functional activity of T-lymphocytes with different grades of differentiation

(2015) A. A. Gutsol et al.   MOLECULAR BIOLOGY

Gene networks specific for innate immunity define post-traumatic stress disorder

(2015) M S Breen et al.   MOLECULAR PSYCHIATRY

Genetic Differences in the Immediate Transcriptome Response to Stress Predict Risk-Related Brain Function and Psychiatric Disorders

(2015) Janine Arloth et al.   NEURON

Dexamethasone Treatment Leads to Enhanced Fear Extinction and Dynamic Fkbp5 Regulation in Amygdala

(2015) Takehito Sawamura et al.   NEUROPSYCHOPHARMACOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

From Receptor Balance to Rational Glucocorticoid Therapy

(2014) E. Ron de Kloet   ENDOCRINOLOGY

Site-specific methylation changes in the glucocorticoid receptor exon 1F promoter in relation to life adversity: systematic review of contributing factors

(2014) Nikolaos P. Daskalakis et al.   Frontiers in Neuroscience

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression

(2013) A. Menke et al.   GENES BRAIN AND BEHAVIOR

Reducing safety-related drug attrition: the use of in vitro pharmacological profiling

(2012) Joanne Bowes et al.   NATURE REVIEWS DRUG DISCOVERY

Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients

(2012) Andreas Menke et al.   NEUROPSYCHOPHARMACOLOGY

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors’ and Longitudinal ‘Targets’

(2012) Annamaria Cattaneo et al.   NEUROPSYCHOPHARMACOLOGY

Minireview: Stress-Related Psychiatric Disorders with Low Cortisol Levels: A Metabolic Hypothesis

(2011) Rachel Yehuda et al.   ENDOCRINOLOGY

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns

(2011) Sam John et al.   NATURE GENETICS

Stimulated Gene Expression Profiles as a Blood Marker of Major Depressive Disorder

(2010) Sabine Spijker et al.   BIOLOGICAL PSYCHIATRY

ToppGene Suite for gene list enrichment analysis and candidate gene prioritization

(2009) J. Chen et al.   NUCLEIC ACIDS RESEARCH

In Vitro Studies are Sometimes Better than Conventional Human Pharmacokinetic In Vivo Studies in Assessing Bioequivalence of Immediate-Release Solid Oral Dosage Forms

(2008) James E. Polli   AAPS Journal

Protein-tyrosine Phosphatase 1B Expression Is Induced by Inflammationin Vivo

(2008) Janice M. Zabolotny et al.   JOURNAL OF BIOLOGICAL CHEMISTRY