Mutations in abnormal spindle disrupt temporal transcription factor expression and trigger immune responses in the Drosophila brain

Traip controls mushroom body size by suppressing mitotic defects

(2022) Ryan S. O'Neill et al.   DEVELOPMENT

A complete temporal transcription factor series in the fly visual system

(2022) Nikolaos Konstantinides et al.   NATURE

DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update)

(2022) Brad T Sherman et al.   NUCLEIC ACIDS RESEARCH

FlyBase: a guided tour of highlighted features

(2022) L Sian Gramates et al.   GENETICS

Spatiotemporal Control of Neuronal Remodeling by Cell Adhesion Molecules: Insights From Drosophila

(2022) Hagar Meltzer et al.   Frontiers in Neuroscience

A Notch-dependent transcriptional mechanism controls expression of temporal patterning factors in Drosophila medulla

(2022) Alokananda Ray et al.   eLife

Molecular Genetics of Microcephaly Primary Hereditary: An Overview

(2021) Nikistratos Siskos et al.   Brain Sciences

Loss of NARS1 impairs progenitor proliferation in cortical brain organoids and leads to microcephaly

(2020) Lu Wang et al.   Nature Communications

Adult Neurogenesis in the Drosophila Brain: The Evidence and the Void

(2020) Guiyi Li et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Polyploidy in the adult Drosophila brain

(2020) Shyama Nandakumar et al.   eLife

Whole Animal Imaging of Drosophila melanogaster using Microcomputed Tomography

(2020) Todd A. Schoborg   Jove-Journal of Visualized Experiments

Transcriptional Programs of Circuit Assembly in the Drosophila Visual System

(2020) Yerbol Z. Kurmangaliyev et al.   NEURON

Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5

(2019) Arvind Kumar Shukla et al.   Cell Reports

Understanding Molecular Mechanisms of the Brain Through Transcriptomics

(2019) Wei Wang et al.   Frontiers in Physiology

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

Micro-computed tomography as a platform for exploring Drosophila development

(2019) Todd A. Schoborg et al.   DEVELOPMENT

Innate immune responses to paraquat exposure in a Drosophila model of Parkinson’s disease

(2019) Urmila Maitra et al.   Scientific Reports

Overexpression of antimicrobial peptides contributes to aging through cytotoxic effects in Drosophila tissues

(2018) Marziyeh Badinloo et al.   ARCHIVES OF INSECT BIOCHEMISTRY AND PHYSIOLOGY

Phenotypic Convergence: Distinct Transcription Factors Regulate Common Terminal Features

(2018) Nikolaos Konstantinides et al.   CELL

Development of Concurrent Retinotopic Maps in the Fly Motion Detection Circuit

(2018) Filipe Pinto-Teixeira et al.   CELL

Same but different: pleiotropy in centrosome-related microcephaly

(2018) Ryan S. O’Neill et al.   MOLECULAR BIOLOGY OF THE CELL

Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size

(2018) Matthew B. Johnson et al.   NATURE

Non-lethal PCR genotyping of single Drosophila

(2018) Gil B. Carvalho et al.   BIOTECHNIQUES

Integrated genome and transcriptome sequencing identifies a noncoding mutation in the genome replication factor DONSON as the cause of microcephaly-micromelia syndrome

(2017) Gilad D. Evrony et al.   GENOME RESEARCH

NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration

(2017) Ilias Kounatidis et al.   Cell Reports

Microcephaly Proteins Wdr62 and Aspm Define a Mother Centriole Complex Regulating Centriole Biogenesis, Apical Complex, and Cell Fate

(2016) Divya Jayaraman et al.   NEURON

A genome-wide resource for the analysis of protein localisation in Drosophila

(2016) Mihail Sarov et al.   eLife

Molecular genetics of human primary microcephaly: an overview

(2015) Muhammad Faheem et al.   BMC Medical Genomics

An Asp–CaM complex is required for centrosome–pole cohesion and centrosome inheritance in neural stem cells

(2015) Todd Schoborg et al.   JOURNAL OF CELL BIOLOGY

Microcephaly protein Asp focuses the minus ends of spindle microtubules at the pole and within the spindle

(2015) Ami Ito et al.   JOURNAL OF CELL BIOLOGY

Genome-wide RNAi screening implicates the E3 ubiquitin ligase Sherpa in mediating innate immune signaling by Toll inDrosophilaadults

(2015) Hirotaka Kanoh et al.   Science Signaling

ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination

(2015) Mario R. Capecchi et al.   Nature Communications

Genome-wide RNAi screening implicates the E3 ubiquitin ligase Sherpa in mediating innate immune signaling by Toll inDrosophilaadults

(2015) Hirotaka Kanoh et al.   Science Signaling

Neurogenesis during development of the vertebrate central nervous system

(2014) J. T. Paridaen et al.   EMBO REPORTS

Diversity and dynamics of the Drosophila transcriptome

(2014) James B. Brown et al.   NATURE

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

midlife crisis encodes a conserved zinc-finger protein required to maintain neuronal differentiation in Drosophila

(2013) T. D. Carney et al.   DEVELOPMENT

A temporal mechanism that produces neuronal diversity in the Drosophila visual center

(2013) Takumi Suzuki et al.   DEVELOPMENTAL BIOLOGY

Brain patterning defects caused by mutations of thetwin of eyelessgene inDrosophila melanogaster

(2013) Katsuo Furukubo-Tokunaga et al.   FLY

The Innate Immune Response Transcription Factor Relish Is Necessary for Neurodegeneration in aDrosophilaModel of Ataxia-Telangiectasia

(2013) Andrew J. Petersen et al.   GENETICS

The microcephaly protein Asp regulates neuroepithelium morphogenesis by controlling the spatial distribution of myosin II

(2013) Maria A. Rujano et al.   NATURE CELL BIOLOGY

Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain

(2013) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microcephaly Gene Links Trithorax and REST/NRSF to Control Neural Stem Cell Proliferation and Differentiation

(2012) Yawei J. Yang et al.   CELL

Drosophila neuroblasts: a model for stem cell biology

(2012) C. C. F. Homem et al.   DEVELOPMENT

ATM kinase inhibition in glial cells activates the innate immune response and causes neurodegeneration in Drosophila

(2012) A. J. Petersen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human ASPM participates in spindle organisation, spindle orientation and cytokinesis

(2010) Julie Higgins et al.   BMC CELL BIOLOGY

Notch signaling regulates neuroepithelial stem cell maintenance and neuroblast formation in Drosophila optic lobe development

(2010) Wei Wang et al.   DEVELOPMENTAL BIOLOGY

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

Enrichment Map: A Network-Based Method for Gene-Set Enrichment Visualization and Interpretation

(2010) Daniele Merico et al.   PLoS One

Compound heterozygous ASPM mutations in Pakistani MCPH families

(2009) Farooq Muhammad et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Genome-wide analysis of Notch signalling in Drosophila by transgenic RNAi

(2009) Jennifer L. Mummery-Widmer et al.   NATURE

G-TRACE: rapid Gal4-based cell lineage analysis in Drosophila

(2009) Cory J Evans et al.   NATURE METHODS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Genome-Wide RNAi Screen Identifies Genes Involved in Intestinal Pathogenic Bacterial Infection

(2009) S. J. F. Cronin et al.   SCIENCE

Alternative Splicing of NURF301 Generates Distinct NURF Chromatin Remodeling Complexes with Altered Modified Histone Binding Specificities

(2009) So Yeon Kwon et al.   PLoS Genetics

Oscillations in Notch Signaling Regulate Maintenance of Neural Progenitors

(2008) Hiromi Shimojo et al.   NEURON