Overexpression of antimicrobial peptides contributes to aging through cytotoxic effects in Drosophila tissues

NF-κB Immunity in the Brain Determines Fly Lifespan in Healthy Aging and Age-Related Neurodegeneration

(2017) Ilias Kounatidis et al.   Cell Reports

The role of peroxiredoxin 4 in inflammatory response and aging

(2016) Vladimir I. Klichko et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pharmacological inhibition of NF-κB prolongs lifespan of Drosophila melanogaster

(2016) Alexey Moskalev et al.   Aging-US

Apoptosis in Drosophila: which role for mitochondria?

(2015) Amandine Clavier et al.   APOPTOSIS

Loss of Drosophila i-AAA protease, dYME1L, causes abnormal mitochondria and apoptotic degeneration

(2015) Y Qi et al.   CELL DEATH AND DIFFERENTIATION

Sterile Inflammation inDrosophila

(2015) Zeeshan Shaukat et al.   MEDIATORS OF INFLAMMATION

Distinct Shifts in Microbiota Composition during Drosophila Aging Impair Intestinal Function and Drive Mortality

(2015) Rebecca I. Clark et al.   Cell Reports

Age-Associated Loss of Lamin-B Leads to Systemic Inflammation and Gut Hyperplasia

(2014) Haiyang Chen et al.   CELL

PGRP-SC2 Promotes Gut Immune Homeostasis to Limit Commensal Dysbiosis and Extend Lifespan

(2014) Linlin Guo et al.   CELL

Exploring the physiology and pathology of aging in the intestine ofDrosophila melanogaster

(2014) Heinrich Jasper   INVERTEBRATE REPRODUCTION & DEVELOPMENT

Microbiota-Induced Changes in Drosophila melanogaster Host Gene Expression and Gut Morphology

(2014) N. A. Broderick et al.   mBio

The Digestive Tract ofDrosophila melanogaster

(2013) Bruno Lemaitre et al.   Annual Review of Genetics

How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: The early history of ERAD

(2013) Patrick G. Needham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The Drosophila IMD pathway in the activation of the humoral immune response

(2013) Anni Kleino et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The Innate Immune Response Transcription Factor Relish Is Necessary for Neurodegeneration in aDrosophilaModel of Ataxia-Telangiectasia

(2013) Andrew J. Petersen et al.   GENETICS

Proinflammatory Cytokines, Aging, and Age-Related Diseases

(2013) Martin Michaud et al.   Journal of the American Medical Directors Association

Dnr1 mutations cause neurodegeneration in Drosophila by activating the innate immune response in the brain

(2013) Y. Cao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila at the intersection of infection, inflammation, and cancer

(2013) Erdem Bangi   Frontiers in Cellular and Infection Microbiology

Aging is associated with chronic innate immune activation and dysregulation of monocyte phenotype and function

(2012) Anna C. Hearps et al.   AGING CELL

Mechanisms of immunosenescence: lessons from models of accelerated immune aging

(2012) Sabine Le Saux et al.   Annals of the New York Academy of Sciences

Characterization of dual effects induced by antimicrobial peptides: Regulated cell death or membrane disruption

(2012) Edgar J. Paredes-Gamero et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Infection-Induced Host Translational Blockage Inhibits Immune Responses and Epithelial Renewal in the Drosophila Gut

(2012) Sveta Chakrabarti et al.   Cell Host & Microbe

Peptidoglycan Sensing by the Receptor PGRP-LE in the Drosophila Gut Induces Immune Responses to Infectious Bacteria and Tolerance to Microbiota

(2012) Virginie Bosco-Drayon et al.   Cell Host & Microbe

Transcription factor zfh1 downregulates Drosophila Imd pathway

(2012) H. Myllymäki et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

The effect of peroxiredoxin 4 on fly physiology is a complex interplay of antioxidant and signaling functions

(2012) Svetlana N. Radyuk et al.   FASEB JOURNAL

The Drosophila inner-membrane protein PMI controls crista biogenesis and mitochondrial diameter

(2012) M. Macchi et al.   JOURNAL OF CELL SCIENCE

Tissue- and Ligand-Specific Sensing of Gram-Negative Infection in Drosophila by PGRP-LC Isoforms and PGRP-LE

(2012) C. Neyen et al.   JOURNAL OF IMMUNOLOGY

The Novel Biological Action of Antimicrobial Peptides via Apoptosis Induction

(2012) Jaeyong Cho   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Correction: Immune Response and Anti-Microbial Peptides Expression in Malpighian Tubules of Drosophila melanogaster Is under Developmental Regulation

(2012) Puja Verma et al.   PLoS One

Alternative pathway of cell death in Drosophila mediated by NF- B transcription factor Relish

(2012) Y. Chinchore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Healthy Aging – Insights from Drosophila

(2012) Konstantin G. Iliadi et al.   Frontiers in Physiology

Induction of yeast apoptosis by an antimicrobial peptide, Papiliocin

(2011) Bomi Hwang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Peroxiredoxin 5 modulates immune response in Drosophila

(2010) Svetlana N. Radyuk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Antimicrobial peptaibols, novel suppressors of tumor cells, targeted calcium-mediated apoptosis and autophagy in human hepatocellular carcinoma cells

(2010) Mei Shi et al.   Molecular Cancer

Too old to fight? Aging and its toll on innate immunity

(2010) G. Hajishengallis   Molecular Oral Microbiology

The antimicrobial peptide cecropin A induces caspase-independent cell death in human promyelocytic leukemia cells

(2010) José Mª. Cerón et al.   PEPTIDES

Differential regulation of mRNA stability controls the transient expression of genes encoding Drosophila antimicrobial peptide with distinct immune response characteristics

(2009) Youheng Wei et al.   NUCLEIC ACIDS RESEARCH

Aging and innate immunity in the mouse: impact of intrinsic and extrinsic factors

(2009) Elizabeth J. Kovacs et al.   TRENDS IN IMMUNOLOGY

Effective but Costly, Evolved Mechanisms of Defense against a Virulent Opportunistic Pathogen in Drosophila melanogaster

(2009) Yixin H. Ye et al.   PLoS Pathogens

Functional analysis of the Drosophila immune response during aging

(2008) Sean Ramsden et al.   AGING CELL

Drosophila peroxiredoxin 5 is the second gene in a dicistronic operon

(2008) Katarzyna Michalak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS