Xinyang tablet ameliorates sepsis-induced myocardial dysfunction by regulating Beclin-1 to mediate macrophage autophagy and M2 polarization through LncSICRNT1 targeting E3 ubiquitin ligase TRAF6

Astragalus polysaccharide ameliorates vascular endothelial dysfunction by stimulating macrophage M2 polarization via potentiating Nrf2/HO-1 signaling pathway

(2023) Wenjun Sha et al.   PHYTOMEDICINE

Role of myeloid derived suppressor cells in sepsis

(2022) M. Malavika et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Identification and Validation of a Ferroptosis-Related Long Non-Coding RNA (FRlncRNA) Signature to Predict Survival Outcomes and the Immune Microenvironment in Patients With Clear Cell Renal Cell Carcinoma

(2022) Zhongbao Zhou et al.   Frontiers in Genetics

Astragalus polysaccharide: a review of its immunomodulatory effect

(2022) Chun-xiao Li et al.   ARCHIVES OF PHARMACAL RESEARCH

Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair-Follicle Neogenesis

(2022) Ying-Ying Teng et al.   Frontiers in Bioengineering and Biotechnology

Astragalus membranaceus and Salvia miltiorrhiza Ameliorate Hypertensive Renal Damage through lncRNA-mRNA Coexpression Network

(2022) Le Zhou et al.   Biomed Research International

Nucleolin Improves Heart Function During Recovery From Myocardial Infarction by Modulating Macrophage Polarization

(2021) Yuting Tang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Elevated LINC01550 induces the apoptosis and cell cycle arrest of melanoma

(2021) Jia Chen et al.   MEDICAL ONCOLOGY

Profiles of differentially expressed long noncoding RNAs and messenger RNAs in the myocardium of septic mice

(2021) Chengbao Li et al.   Annals of Translational Medicine

Xinyang Tablet inhibits MLK3-mediated pyroptosis to attenuate inflammation and cardiac dysfunction in pressure overload

(2021) Junyan Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

A Retrospective Observational Study of the Association Between Plasma Levels of Interleukin 8 in 42 Patients with Sepsis-Induced Myocardial Dysfunction at a Single Center Between 2017 and 2020

(2021) XiaoYing Chen et al.   MEDICAL SCIENCE MONITOR

Il12a Deletion Aggravates Sepsis-Induced Cardiac Dysfunction by Regulating Macrophage Polarization

(2021) Zhen Wang et al.   Frontiers in Pharmacology

Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling

(2021) Lianlian Tian et al.   Frontiers in Immunology

Hydrogen-rich saline regulates the polarization and apoptosis of alveolar macrophages and attenuates lung injury via suppression of autophagy in septic rats

(2021) Peng Qiu et al.   Annals of Translational Medicine

Traditional Chinese medicine enhances myocardial metabolism during heart failure

(2021) Wang Shao-mei et al.   BIOMEDICINE & PHARMACOTHERAPY

Neuropeptide W Attenuates Oxidative Multi-Organ Injury in Rats Induced with Intra-Abdominal Sepsis

(2021) Ali Emre Atici et al.   INFLAMMATION

Long noncoding RNA MAPKAPK5-AS1 promoted lipopolysaccharide-induced inflammatory damage in the myocardium by sponging microRNA-124-3p/E2F3

(2021) Weiwei Chen et al.   MOLECULAR MEDICINE

Salvianolic acid B regulates macrophage polarization in ischemic/reperfused hearts by inhibiting mTORC1-induced glycolysis

(2020) Meina Zhao et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Geniposide protects against sepsis-induced myocardial dysfunction through AMPKα-dependent pathway

(2020) Peng Song et al.   FREE RADICAL BIOLOGY AND MEDICINE

Baoyuan decoction ameliorates apoptosis via AT1-CARP signaling pathway in H9C2 cells and heart failure post-acute myocardial infarction rats

(2020) Xiaoping Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

LncRNA MIAT Promotes Inflammation and Oxidative Stress in Sepsis-Induced Cardiac Injury by Targeting miR-330-5p/TRAF6/NF-κB Axis

(2020) Peng-Cheng Xing et al.   BIOCHEMICAL GENETICS

miR-214-3p Attenuates Sepsis-Induced Myocardial Dysfunction in Mice by Inhibiting Autophagy through PTEN/AKT/mTOR Pathway

(2020) Zhenzhen Sang et al.   Biomed Research International

Heat shock protein 70 expression protects against sepsis-associated cardiomyopathy by inhibiting autophagy

(2020) Xiaofeng Wang et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Typically inhibiting USP14 promotes autophagy in M1-like macrophages and alleviates CLP-induced sepsis

(2020) Fang Xu et al.   Cell Death & Disease

RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance

(2020) Jianmin Chen et al.   Frontiers in Immunology

Effectiveness and safety of Xinyin tablet in treatment of chronic heart failure

(2020) Qingqing Liu et al.   MEDICINE

Long non-coding RNAs as the regulators and targets of macrophage M2 polarization

(2020) Rong Dong et al.   LIFE SCIENCES

Icariin attenuates endothelial-mesenchymal transition via H19/miR-148b-3p/ELF5 in ox-LDL-stimulated HUVECs

(2020) Shan Liu et al.   Molecular Therapy-Nucleic Acids

Attenuation of Sepsis-Induced Cardiomyopathy by Regulation of MicroRNA-23b Is Mediated Through Targeting of MyD88-Mediated NF-κB Activation

(2019) Chao Cao et al.   INFLAMMATION

TRAF6 inhibits colorectal cancer metastasis through regulating selective autophagic CTNNB1/β-catenin degradation and is targeted for GSK3B/GSK3β-mediated phosphorylation and degradation

(2019) Hua Wu et al.   Autophagy

Stachydrine prevents LPS‐induced bone loss by inhibiting osteoclastogenesis via NF‐κB and Akt signalling

(2019) Jiahong Meng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Characterization of Long Noncoding RNA and mRNA Profiles in Sepsis-Induced Myocardial Depression

(2019) Tie-Ning Zhang et al.   Molecular Therapy-Nucleic Acids

Trichostatin A modulates the macrophage phenotype by enhancing autophagy to reduce inflammation during polymicrobial sepsis

(2019) Shu-Nan Cui et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Autophagy and Macrophage Functions: Inflammatory Response and Phagocytosis

(2019) Ming-Yue Wu et al.   Cells

Autophagy and Inflammation

(2018) Yu Matsuzawa-Ishimoto et al.   Annual Review of Immunology

Inhibition of TRAF6 ubiquitin-ligase activity by PRDX1 leads to inhibition of NFKB activation and autophagy activation

(2018) Yoon Min et al.   Autophagy

The Surviving Sepsis Campaign Bundle: 2018 update

(2018) Mitchell M. Levy et al.   INTENSIVE CARE MEDICINE

Inhibition of COX-2/mPGES-1 and 5-LOX in macrophages by leonurine ameliorates monosodium urate crystal-induced inflammation

(2018) Yanzhuo Liu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Tumor necrosis factor receptor-associated factor 6 as a nuclear factor kappa B-modulating therapeutic target in cardiovascular diseases: at the heart of it all

(2018) Muhammad Abdullah et al.   Translational Research

Review: the Role and Mechanisms of Macrophage Autophagy in Sepsis

(2018) Peng Qiu et al.   INFLAMMATION

miR-146a Attenuates Sepsis-Induced Myocardial Dysfunction by Suppressing IRAK1 and TRAF6 via Targeting ErbB4 Expression

(2018) Rui An et al.   Oxidative Medicine and Cellular Longevity

Activation of RIG-I-Mediated Antiviral Signaling Triggers Autophagy Through the MAVS-TRAF6-Beclin-1 Signaling Axis

(2018) Na-Rae Lee et al.   Frontiers in Immunology

Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016

(2017) Andrew Rhodes et al.   INTENSIVE CARE MEDICINE

Regulation of the Tumor-Suppressor BECLIN 1 by Distinct Ubiquitination Cascades

(2017) Fahd Boutouja et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytotherapy with M1-polarized macrophages ameliorates liver fibrosis by modulating immune microenvironment in mice

(2017) Peng-Fei Ma et al.   JOURNAL OF HEPATOLOGY

Enhanced Glycolytic Metabolism Contributes to Cardiac Dysfunction in Polymicrobial Sepsis

(2017) Zhibo Zheng et al.   JOURNAL OF INFECTIOUS DISEASES

Myricetin attenuated LPS induced cardiac injury in vivo and in vitro

(2017) Nan Zhang et al.   PHYTOTHERAPY RESEARCH

Anti-inflammatory effect of IL-10 mediated by metabolic reprogramming of macrophages

(2017) W. K. Eddie Ip et al.   SCIENCE

The LPS-inducible lncRNA Mirt2 is a negative regulator of inflammation

(2017) Meng Du et al.   Nature Communications

MicroRNA expression profiling of Leishmania donovani-infected host cells uncovers the regulatory role of MIR30A-3p in host autophagy

(2016) Alok Kumar Singh et al.   Autophagy

The transcriptional coregulator GRIP1 controls macrophage polarization and metabolic homeostasis

(2016) Maddalena Coppo et al.   Nature Communications

Complement C5a exacerbates acute lung injury induced through autophagy-mediated alveolar macrophage apoptosis

(2014) R Hu et al.   Cell Death & Disease

Targeting NFKB by autophagy to polarize hepatoma-associated macrophage differentiation

(2013) Chih-Peng Chang et al.   Autophagy

Characterization of Cardiac Dysfunction in Sepsis

(2013) Ahmed Zaky et al.   SHOCK

Gram-positive and gram-negative bacterial toxins in sepsis

(2013) Girish Ramachandran   Virulence

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Macrophages, innate immunity and cancer: balance, tolerance, and diversity

(2010) Alberto Mantovani et al.   CURRENT OPINION IN IMMUNOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

TRAF6 and A20 Regulate Lysine 63-Linked Ubiquitination of Beclin-1 to Control TLR4-Induced Autophagy

(2010) C. S. Shi et al.   Science Signaling