Proteins rather than mRNAs regulate nucleation and persistence of Oskar germ granules in Drosophila

RNA at the surface of phase-separated condensates impacts their size and number

(2022) Audrey Cochard et al.   BIOPHYSICAL JOURNAL

RNA is required for the integrity of multiple nuclear and cytoplasmic membrane‐less RNP granules

(2022) Carolyn J Decker et al.   EMBO JOURNAL

Membrane surfaces regulate assembly of ribonucleoprotein condensates

(2022) Wilton T. Snead et al.   NATURE CELL BIOLOGY

Germ granules and gene regulation in the Caenorhabditis elegans germline

(2022) Carolyn M Phillips et al.   GENETICS

In vivo reconstitution finds multivalent RNA-RNA interactions as drivers of mesh-like condensates

(2021) Weirui Ma et al.   eLife

Emerging View on the Molecular Functions of Sec62 and Sec63 in Protein Translocation

(2021) Sung-jun Jung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

(2020) Devin Tauber et al.   CELL

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

Makorin 1 controls embryonic patterning by alleviating Bruno1-mediated repression of oskar translation

(2020) Annabelle Dold et al.   PLoS Genetics

Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

(2020) Chih-Yung S Lee et al.   eLife

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

(2020) Peiguo Yang et al.   CELL

Sequence-Independent Self-Assembly of Germ Granule mRNAs into Homotypic Clusters

(2020) Tatjana Trcek et al.   MOLECULAR CELL

RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia

(2020) Gregory G Fuller et al.   eLife

RNA Granules: A View from the RNA Perspective

(2020) Siran Tian et al.   MOLECULES

RPS28B mRNA acts as a scaffold promoting cis-translational interaction of proteins driving P-body assembly

(2020) Nikita Fernandes et al.   NUCLEIC ACIDS RESEARCH

Ribosomal protein RPL26 is the principal target of UFMylation

(2019) Christopher P. Walczak et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid and efficient generation of GFP ‐knocked‐in Drosophila by the CRISPR ‐Cas9‐mediated genome editing

(2019) Hirono Kina et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Germ granules in Drosophila

(2019) Tatjana Trcek et al.   TRAFFIC

Germ Cell Lineage Homeostasis in Drosophila Requires the Vasa RNA Helicase

(2019) Zeljko Durdevic et al.   GENETICS

DEAD-box ATPases are global regulators of phase-separated organelles

(2019) Maria Hondele et al.   NATURE

Nuclear Pores Assemble from Nucleoporin Condensates During Oogenesis

(2019) Bernhard Hampoelz et al.   CELL

UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis

(2019) Lihui Wang et al.   CELL RESEARCH

The Role of Post-Translational Modifications in the Phase Transitions of Intrinsically Disordered Proteins

(2019) Izzy Owen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies

(2018) Briana Van Treeck et al.   CELL

The molecular language of membraneless organelles

(2018) Edward Gomes et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase transitioned nuclear Oskar promotes cell division of Drosophila primordial germ cells

(2018) Kathryn E Kistler et al.   eLife

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

Remodeling of the endoplasmic reticulum in Caenorhabditis elegans oocytes is regulated by CGH-1

(2018) Shaughna Langerak et al.   GENESIS

The LOTUS domain is a conserved DEAD-box RNA helicase regulator essential for the recruitment of Vasa to the germ plasm and nuage

(2017) Mandy Jeske et al.   GENES & DEVELOPMENT

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

(2017) Arnaud Hubstenberger et al.   MOLECULAR CELL

ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure

(2016) Saumya Jain et al.   CELL

Long Oskar Controls Mitochondrial Inheritance in Drosophila melanogaster

(2016) Thomas Ryan Hurd et al.   DEVELOPMENTAL CELL

mRNA quantification using single-molecule FISH in Drosophila embryos

(2016) Tatjana Trcek et al.   Nature Protocols

Hypo- and Hyper-Assembly Diseases of RNA–Protein Complexes

(2016) Siddharth Shukla et al.   TRENDS IN MOLECULAR MEDICINE

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

(2016) Jarrett Smith et al.   eLife

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

Independent and coordinate trafficking of single Drosophila germ plasm mRNAs

(2015) Shawn C. Little et al.   NATURE CELL BIOLOGY

Structure ofDrosophilaOskar reveals a novel RNA binding protein

(2015) Na Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Drosophila germ granules are structured and contain homotypic mRNA clusters

(2015) Tatjana Trcek et al.   Nature Communications

The Crystal Structure of the Drosophila Germline Inducer Oskar Identifies Two Domains with Distinct Vasa Helicase- and RNA-Binding Activities

(2015) Mandy Jeske et al.   Cell Reports

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

Instant super-resolution imaging in live cells and embryos via analog image processing

(2013) Andrew G York et al.   NATURE METHODS

Germ Plasm Anchoring Is a Dynamic State that Requires Persistent Trafficking

(2013) Kristina S. Sinsimer et al.   Cell Reports

Single-molecule assays reveal that RNA localization signals regulate dynein–dynactin copy number on individual transcript cargoes

(2012) Mamta Amrute-Nayak et al.   NATURE CELL BIOLOGY

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Nuclear pore complex composition: a new regulator of tissue-specific and developmental functions

(2012) Marcela Raices et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Control of RNP motility and localization by a splicing-dependent structure in oskar mRNA

(2012) Sanjay Ghosh et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Transport of Germ Plasm on Astral Microtubules Directs Germ Cell Development in Drosophila

(2011) Dorothy A. Lerit et al.   CURRENT BIOLOGY

Drosophila Mon2 couples Oskar-induced endocytosis with actin remodeling for cortical anchorage of the germ plasm

(2011) T. Tanaka et al.   DEVELOPMENT

Long-term live imaging provides new insight into stem cell regulation and germline-soma coordination in the Drosophila ovary

(2011) L. X. Morris et al.   DEVELOPMENT

Assembly of RNP granules in stressed and aging oocytes requires nucleoporins and is coordinated with nuclear membrane blebbing

(2011) Joseph R. Patterson et al.   DEVELOPMENTAL BIOLOGY

Diverse roles of the scaffolding protein RanBPM

(2011) Bharathi Suresh et al.   DRUG DISCOVERY TODAY

A transgenic mouse for in vivo detection of endogenous labeled mRNA

(2011) Timothée Lionnet et al.   NATURE METHODS

Systematic image-driven analysis of the spatial Drosophila embryonic expression landscape

(2010) Erwin Frise et al.   Molecular Systems Biology

Germ Cells Are Forever

(2008) Ryan M. Cinalli et al.   CELL

The endocytic pathway acts downstream of Oskar in Drosophila germ plasm assembly

(2008) T. Tanaka et al.   DEVELOPMENT

Isolation of new polar granule components in Drosophila reveals P body and ER associated proteins

(2008) Travis Thomson et al.   MECHANISMS OF DEVELOPMENT

Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells

(2008) Kazuko Hanyu-Nakamura et al.   NATURE