Recruitment of mRNAs to P granules by condensation with intrinsically-disordered proteins

Membraneless organelles: P granules in C. elegans

(2019) Elisabeth A. Marnik et al.   TRAFFIC

A gel phase promotes condensation of liquid P granules in Caenorhabditis elegans embryos

(2019) Andrea Putnam et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates

(2019) Simon Alberti et al.   CELL

Germ granules in Drosophila

(2019) Tatjana Trcek et al.   TRAFFIC

Germ Granules Coordinate RNA-Based Epigenetic Inheritance Pathways

(2019) Anne E. Dodson et al.   DEVELOPMENTAL CELL

P Granules Protect RNA Interference Genes from Silencing by piRNAs

(2019) John Paul T. Ouyang et al.   DEVELOPMENTAL CELL

Transcriptome-Wide Comparison of Stress Granules and P-Bodies Reveals that Translation Plays a Major Role in RNA Partitioning

(2019) Tyler Matheny et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of piRNA Binding Sites Reveals the Argonaute Regulatory Landscape of the C. elegans Germline

(2018) En-Zhi Shen et al.   CELL

RNA-protein interactions in an unstructured context

(2018) Bojan Zagrovic et al.   FEBS LETTERS

A brave new world of RNA-binding proteins

(2018) Matthias W. Hentze et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

RNA self-assembly contributes to stress granule formation and defining the stress granule transcriptome

(2018) Briana Van Treeck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

Emerging Roles for Intermolecular RNA-RNA Interactions in RNP Assemblies

(2018) Briana Van Treeck et al.   CELL

The P Granules of C. elegans: A Genetic Model for the Study of RNA–Protein Condensates

(2018) Geraldine Seydoux   JOURNAL OF MOLECULAR BIOLOGY

Multiple Modes of Protein–Protein Interactions Promote RNP Granule Assembly

(2018) Tanja Mittag et al.   JOURNAL OF MOLECULAR BIOLOGY

Stress Granules and Processing Bodies in Translational Control

(2018) Pavel Ivanov et al.   Cold Spring Harbor Perspectives in Biology

Single molecule dynamics of the P granule scaffold MEG-3 in the C. elegans zygote

(2018) Youjun Wu et al.   MOLECULAR BIOLOGY OF THE CELL

Functional equivalence of germ plasm organizers

(2018) Pritesh Krishnakumar et al.   PLoS Genetics

LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition inCaenorhabditis elegans

(2017) Tatsuya Tsukamoto et al.   GENETICS

Stress-specific differences in assembly and composition of stress granules and related foci

(2017) Anaïs Aulas et al.   JOURNAL OF CELL SCIENCE

Precision genome editing using CRISPR-Cas9 and linear repair templates in C. elegans

(2017) Alexandre Paix et al.   METHODS

P-Body Purification Reveals the Condensation of Repressed mRNA Regulons

(2017) Arnaud Hubstenberger et al.   MOLECULAR CELL

The Stress Granule Transcriptome Reveals Principles of mRNA Accumulation in Stress Granules

(2017) Anthony Khong et al.   MOLECULAR CELL

eIF5A Functions Globally in Translation Elongation and Termination

(2017) Anthony P. Schuller et al.   MOLECULAR CELL

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Convergent evolution of germ granule nucleators: A hypothesis

(2017) Arpita Kulkarni et al.   Stem Cell Research

Nanos promotes epigenetic reprograming of the germline by down-regulation of the THAP transcription factor LIN-15B

(2017) Chih-Yung Sean Lee et al.   eLife

LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition inCaenorhabditis elegans

(2017) Tatsuya Tsukamoto et al.   GENETICS

Polar Positioning of Phase-Separated Liquid Compartments in Cells Regulated by an mRNA Competition Mechanism

(2016) Shambaditya Saha et al.   CELL

G3BP–Caprin1–USP10 complexes mediate stress granule condensation and associate with 40S subunits

(2016) Nancy Kedersha et al.   JOURNAL OF CELL BIOLOGY

Sequence-dependent but not sequence-specific piRNA adhesion traps mRNAs to the germ plasm

(2016) Anastassios Vourekas et al.   NATURE

Spatial patterning of P granules by RNA-induced phase separation of the intrinsically-disordered protein MEG-3

(2016) Jarrett Smith et al.   eLife

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

A general method to improve fluorophores for live-cell and single-molecule microscopy

(2015) Jonathan B Grimm et al.   NATURE METHODS

HISAT: a fast spliced aligner with low memory requirements

(2015) Daehwan Kim et al.   NATURE METHODS

Structure ofDrosophilaOskar reveals a novel RNA binding protein

(2015) Na Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TRIM-NHL proteins in development and disease

(2015) Cristina Tocchini et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Liquid-Liquid Phase Separation in Biology

(2014) Anthony A. Hyman et al.   Annual Review of Cell and Developmental Biology

HTSeq--a Python framework to work with high-throughput sequencing data

(2014) S. Anders et al.   BIOINFORMATICS

Skewer: a fast and accurate adapter trimmer for next-generation sequencing paired-end reads

(2014) Hongshan Jiang et al.   BMC BIOINFORMATICS

Scalable and Versatile Genome Editing Using Linear DNAs with Microhomology to Cas9 Sites in Caenorhabditis elegans

(2014) Alexandre Paix et al.   GENETICS

Free mRNA in excess upon polysome dissociation is a scaffold for protein multimerization to form stress granules

(2014) Ouissame Bounedjah et al.   NUCLEIC ACIDS RESEARCH

Regulation of RNA granule dynamics by phosphorylation of serine-rich, intrinsically disordered proteins in C. elegans

(2014) Jennifer T Wang et al.   eLife

iCLIP: Protein–RNA interactions at nucleotide resolution

(2013) Ina Huppertz et al.   METHODS

Widespread Regulation of Translation by Elongation Pausing in Heat Shock

(2013) Reut Shalgi et al.   MOLECULAR CELL

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Getting RNA and Protein in Phase

(2012) Stephanie C. Weber et al.   CELL

Genome-Wide Analysis of GLD-1–Mediated mRNA Regulation Suggests a Role in mRNA Storage

(2012) Claudia Scheckel et al.   PLoS Genetics

Critical roles of RNA helicase DDX3 and its interactions with eIF4E/PABP1 in stress granule assembly and stress response

(2011) Jing-Wen Shih et al.   BIOCHEMICAL JOURNAL

P granules extend the nuclear pore complex environment in theC. elegansgerm line

(2011) Dustin L. Updike et al.   JOURNAL OF CELL BIOLOGY

PGL proteins self associate and bind RNPs to mediate germ granule assembly inC. elegans

(2011) Momoyo Hanazawa et al.   JOURNAL OF CELL BIOLOGY

Eggshell Chitin and Chitin-Interacting Proteins Prevent Polyspermy in C. elegans

(2010) Wendy L. Johnston et al.   CURRENT BIOLOGY

Cytoplasmic Partitioning of P Granule Components Is Not Required to Specify the Germline in C. elegans

(2010) C. M. Gallo et al.   SCIENCE

Eukaryotic Stress Granules: The Ins and Outs of Translation

(2009) J. Ross Buchan et al.   MOLECULAR CELL

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE

Multiple maternal proteins coordinate to restrict the translation of C. elegans nanos-2 to primordial germ cells

(2008) S. Jadhav et al.   DEVELOPMENT

Processing bodies and germ granules are distinct RNA granules that interact in C. elegans embryos

(2008) Christopher M. Gallo et al.   DEVELOPMENTAL BIOLOGY

MEG-1 and MEG-2 Are Embryo-Specific P-Granule Components Required for Germline Development in Caenorhabditis elegans

(2008) Stefanie W. Leacock et al.   GENETICS

Protection of specific maternal messenger RNAs by the P body protein CGH-1 (Dhh1/RCK) duringCaenorhabditis elegansoogenesis

(2008) Peter R. Boag et al.   JOURNAL OF CELL BIOLOGY

Imaging individual mRNA molecules using multiple singly labeled probes

(2008) Arjun Raj et al.   NATURE METHODS