Membrane surfaces regulate assembly of ribonucleoprotein condensates

Quantifying Viscosity and Surface Tension of Multi-Component Protein-Nucleic Acid Condensates

(2021) Ibraheem Alshareedah et al.   BIOPHYSICAL JOURNAL

Wetting regulates autophagy of phase-separated compartments and the cytosol

(2021) Jaime Agudo-Canalejo et al.   NATURE

Chromatin mechanics dictates subdiffusion and coarsening dynamics of embedded condensates

(2021) Daniel S. W. Lee et al.   Nature Physics

Ligand effects on phase separation of multivalent macromolecules

(2021) Kiersten M. Ruff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane-associated phase separation: organization and function emerge from a two-dimensional milieu

(2021) Jonathon A Ditlev   Journal of Molecular Cell Biology

HP1 proteins compact DNA into mechanically and positionally stable phase separated domains

(2021) Madeline M Keenen et al.   eLife

Liquid-like protein interactions catalyse assembly of endocytic vesicles

(2021) Kasey J. Day et al.   NATURE CELL BIOLOGY

Impact of Nanoscale Hindrances on the Relationship between Lipid Packing and Diffusion in Model Membranes

(2020) Daniel Beckers et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Phase separation organizes the site of autophagosome formation

(2020) Yuko Fujioka et al.   NATURE

Endoplasmic reticulum contact sites regulate the dynamics of membraneless organelles

(2020) Jason E. Lee et al.   SCIENCE

Phosphoregulation provides specificity to biomolecular condensates in the cell cycle and cell polarity

(2020) Therese M. Gerbich et al.   JOURNAL OF CELL BIOLOGY

Dynamic metastable long-living droplets formed by sticker-spacer proteins

(2020) Srivastav Ranganathan et al.   eLife

Phase Separation in Membrane Biology: The Interplay between Membrane-Bound Organelles and Membraneless Condensates

(2020) Yan G. Zhao et al.   DEVELOPMENTAL CELL

Coupled Membrane Lipid Miscibility and Phosphotyrosine-Driven Protein Condensation Phase Transitions

(2020) Jean K. Chung et al.   BIOPHYSICAL JOURNAL

RIM and RIM-BP Form Presynaptic Active-Zone-like Condensates via Phase Separation

(2019) Xiandeng Wu et al.   MOLECULAR CELL

A molecular assembly phase transition and kinetic proofreading modulate Ras activation by SOS

(2019) William Y. C. Huang et al.   SCIENCE

Stoichiometry controls activity of phase-separated clusters of actin signaling proteins

(2019) Lindsay B. Case et al.   SCIENCE

Physics of Active Emulsions

(2019) Christoph A. Weber et al.   REPORTS ON PROGRESS IN PHYSICS

Regulation of Transmembrane Signaling by Phase Separation

(2019) Lindsay B. Case et al.   Annual Review of Biophysics

Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites

(2019) Marta Alenquer et al.   Nature Communications

A composition-dependent molecular clutch between T cell signaling condensates and actin

(2019) Jonathon A Ditlev et al.   eLife

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

Microtubules gate tau condensation to spatially regulate microtubule functions

(2019) Ruensern Tan et al.   NATURE CELL BIOLOGY

Kinetically distinct phases of tau on microtubules regulate kinesin motors and severing enzymes

(2019) Valerie Siahaan et al.   NATURE CELL BIOLOGY

Organization of Chromatin by Intrinsic and Regulated Phase Separation

(2019) Bryan A. Gibson et al.   CELL

The Control Centers of Biomolecular Phase Separation: How Membrane Surfaces, PTMs, and Active Processes Regulate Condensation

(2019) Wilton T. Snead et al.   MOLECULAR CELL

Functional Domains of NEAT1 Architectural lncRNA Induce Paraspeckle Assembly through Phase Separation

(2018) Tomohiro Yamazaki et al.   MOLECULAR CELL

Chemical-Reaction-Controlled Phase Separated Drops: Formation, Size Selection, and Coarsening

(2018) Jean David Wurtz et al.   PHYSICAL REVIEW LETTERS

Physical principles of intracellular organization via active and passive phase transitions

(2018) Joel Berry et al.   REPORTS ON PROGRESS IN PHYSICS

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

A liquid phase of synapsin and lipid vesicles

(2018) Dragomir Milovanovic et al.   SCIENCE

Reconstituted Postsynaptic Density as a Molecular Platform for Understanding Synapse Formation and Plasticity

(2018) Menglong Zeng et al.   CELL

Rotational and translational diffusion of size-dependent fluorescent probes in homogeneous and heterogeneous environments

(2018) Hong Bok Lee et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

A Membraneless Organelle Associated with the Endoplasmic Reticulum Enables 3′UTR-Mediated Protein-Protein Interactions

(2018) Weirui Ma et al.   CELL

BAR scaffolds drive membrane fission by crowding disordered domains

(2018) Wilton T. Snead et al.   JOURNAL OF CELL BIOLOGY

Phase separation drives heterochromatin domain formation

(2017) Amy R. Strom et al.   NATURE

Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin

(2017) Adam G. Larson et al.   NATURE

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Amyotrophic lateral sclerosis-linked mutations increase the viscosity of liquid-like TDP-43 RNP granules in neurons

(2017) Pallavi P. Gopal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Compositional Control of Phase-Separated Cellular Bodies

(2016) Salman F. Banani et al.   CELL

Phosphotyrosine-mediated LAT assembly on membranes drives kinetic bifurcation in recruitment dynamics of the Ras activator SOS

(2016) William Y. C. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phase separation of signaling molecules promotes T cell receptor signal transduction

(2016) Xiaolei Su et al.   SCIENCE

The impact of physiological crowding on the diffusivity of membrane bound proteins

(2016) Justin R. Houser et al.   Soft Matter

PolyQ-dependent RNA–protein assemblies control symmetry breaking

(2015) ChangHwan Lee et al.   JOURNAL OF CELL BIOLOGY

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins

(2015) Yuan Lin et al.   MOLECULAR CELL

Polymer physics of intracellular phase transitions

(2015) Clifford P. Brangwynne et al.   Nature Physics

Diversity and selectivity in mRNA translation on the endoplasmic reticulum

(2015) David W. Reid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Suppression of Ostwald ripening in active emulsions

(2015) David Zwicker et al.   PHYSICAL REVIEW E

Cadmium–cysteine coordination in the BK inner pore region and its structural and functional implications

(2015) Yu Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF and IL-1 exhibit distinct ubiquitin requirements for inducing NEMO–IKK supramolecular structures

(2014) Nadine Tarantino et al.   JOURNAL OF CELL BIOLOGY

Phase transitions of multivalent proteins can promote clustering of membrane receptors

(2014) Sudeep Banjade et al.   eLife

Coarsening Dynamics of Domains in Lipid Membranes

(2013) Cynthia A. Stanich et al.   BIOPHYSICAL JOURNAL

Protein Aggregation Behavior Regulates Cyclin Transcript Localization and Cell-Cycle Control

(2013) ChangHwan Lee et al.   DEVELOPMENTAL CELL

Advances in Analysis of Low Signal-to-Noise Images Link Dynamin and AP2 to the Functions of an Endocytic Checkpoint

(2013) François Aguet et al.   DEVELOPMENTAL CELL

Phase transitions in the assembly of multivalent signalling proteins

(2012) Pilong Li et al.   NATURE

Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation

(2009) C. P. Brangwynne et al.   SCIENCE