METTL3-mediated m6A methylation regulates ovarian cancer progression by recruiting myeloid-derived suppressor cells

METTL3-dependent m6A modification programs T follicular helper cell differentiation

(2021) Yingpeng Yao et al.   Nature Communications

RNA m6A methylation orchestrates cancer growth and metastasis via macrophage reprogramming

(2021) Huilong Yin et al.   Nature Communications

METTL3-mediated m6A modification regulates cell cycle progression of dental pulp stem cells

(2021) Haiyun Luo et al.   Stem Cell Research & Therapy

The Role of Myeloid-Derived Suppressor Cells (MDSCs) in the Development and/or Progression of Endometriosis-State of the Art

(2021) Dorota Suszczyk et al.   Cells

Tissue-resident macrophages in omentum promote metastatic spread of ovarian cancer

(2020) Anders Etzerodt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Tumor-associated macrophages promote ovarian cancer cell migration by secreting transforming growth factor beta induced (TGFBI) and tenascin C

(2020) Anna Mary Steitz et al.   Cell Death & Disease

Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation

(2020) Zhong Zheng et al.   Cell Reports

Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis

(2020) Houjun Xia et al.   JCI Insight

m 6 A RNA methyltransferases METTL3/14 regulate immune responses to anti‐PD‐1 therapy

(2020) Lingling Wang et al.   EMBO JOURNAL

METTL3 potentiates resistance to cisplatin through m 6 A modification of TFAP2C in seminoma

(2020) Jingchao Wei et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

IL1β promotes immune suppression in the tumor microenvironment independent of the inflammasome and gasdermin D

(2020) Mate Kiss et al.   Cancer Immunology Research

The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network

(2019) Maosheng Cheng et al.   ONCOGENE

Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

(2019) Qinglei Gao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression

(2019) Pieter Goossens et al.   Cell Metabolism

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

(2019) Victor S. Tapia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Stage-specific requirement for Mettl3-dependent m6A mRNA methylation during haematopoietic stem cell differentiation

(2019) Heather Lee et al.   NATURE CELL BIOLOGY

m6A Regulates Neurogenesis and Neuronal Development by Modulating Histone Methyltransferase Ezh2

(2019) Junchen Chen et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Myeloid Derived Suppressor Cells: Key Drivers of Immunosuppression in Ovarian Cancer

(2019) Thaïs Baert et al.   Frontiers in Immunology

Dynamic transcriptomic m6A decoration: writers, erasers, readers and functions in RNA metabolism

(2018) Ying Yang et al.   CELL RESEARCH

Mettl3–Mettl14 methyltransferase complex regulates the quiescence of adult hematopoietic stem cells

(2018) Qi Jason Yao et al.   CELL RESEARCH

Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

(2018) Mana Taki et al.   Nature Communications

METTL3-mediated m6A modification is required for cerebellar development

(2018) Chen-Xin Wang et al.   PLOS BIOLOGY

Macrophages of distinct origins contribute to tumor development in the lung

(2018) Pierre-Louis Loyher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum

(2018) WonJae Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Effect of interleukin-1β inhibition with canakinumab on incident lung cancer in patients with atherosclerosis: exploratory results from a randomised, double-blind, placebo-controlled trial

(2017) Paul M Ridker et al.   LANCET

m6A mRNA methylation controls T cell homeostasis by targeting the IL-7/STAT5/SOCS pathways

(2017) Hua-Bing Li et al.   NATURE

The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells

(2017) Ly P Vu et al.   NATURE MEDICINE

m 6 A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells

(2017) Qi Cui et al.   Cell Reports

Myeloid-Derived Suppressor Cells

(2017) Dmitry I. Gabrilovich   Cancer Immunology Research

The Unique Molecular and Cellular Microenvironment of Ovarian Cancer

(2017) Thomas Worzfeld et al.   Frontiers in Oncology

METTL14 suppresses the metastatic potential of hepatocellular carcinoma by modulatingN6-methyladenosine-dependent primary MicroRNA processing

(2016) Jin-zhao Ma et al.   HEPATOLOGY

Tissue-Resident Macrophage Ontogeny and Homeostasis

(2016) Florent Ginhoux et al.   IMMUNITY

Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer

(2016) Mingzhu Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment

(2016) Vinit Kumar et al.   TRENDS IN IMMUNOLOGY

The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization

(2016) Florian Finkernagel et al.   Oncotarget

Targeting myeloid cells in the tumor microenvironment enhances vaccine efficacy in murine epithelial ovarian cancer

(2015) Anm Nazmul H. Khan et al.   Oncotarget

Elevated endoplasmic reticulum stress reinforced immunosuppression in the tumor microenvironment via myeloid-derived suppressor cells

(2015) Bo-Ra Lee et al.   Oncotarget

Murine CD27(-) V 6(+)    T cells producing IL-17A promote ovarian cancer growth via mobilization of protumor small peritoneal macrophages

(2014) M. Rei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Transcription Factor Gata6 Links Tissue Macrophage Phenotype and Proliferative Renewal

(2014) M. Rosas et al.   SCIENCE

A high M1/M2 ratio of tumor-associated macrophages is associated with extended survival in ovarian cancer patients

(2014) Meiying Zhang et al.   Journal of Ovarian Research

Expression of the Homeobox Gene HOXA9 in Ovarian Cancer Induces Peritoneal Macrophages to Acquire an M2 Tumor-Promoting Phenotype

(2013) Song Yi Ko et al.   AMERICAN JOURNAL OF PATHOLOGY

Fusion-Derived Epithelial Cancer Cells Express Hematopoietic Markers and Contribute to Stem Cell and Migratory Phenotype in Ovarian Carcinoma

(2013) M. Ramakrishnan et al.   CANCER RESEARCH

CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-β

(2013) J. Jablonska et al.   INTERNATIONAL JOURNAL OF CANCER

The Role of IL-1  in the Early Tumor Cell-Induced Angiogenic Response

(2013) Y. Carmi et al.   JOURNAL OF IMMUNOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Tissue-resident macrophages

(2013) Luke C Davies et al.   NATURE IMMUNOLOGY

Macrophages in Tumor Microenvironments and the Progression of Tumors

(2012) Ning-Bo Hao et al.   Clinical & Developmental Immunology

Interleukin-1, inflammasomes, autoinflammation and the skin

(2012) E Contassot et al.   SWISS MEDICAL WEEKLY

Combined Blockade of Integrin- 4 1 Plus Cytokines SDF-1  or IL-1  Potently Inhibits Tumor Inflammation and Growth

(2011) M. C. Schmid et al.   CANCER RESEARCH

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

(2011) Bin-Zhi Qian et al.   NATURE

Role of the Inflammasome, IL-1β, and IL-18 in Bacterial Infections

(2011) Manoranjan Sahoo et al.   TheScientificWorldJOURNAL

Two physically, functionally, and developmentally distinct peritoneal macrophage subsets

(2010) E. E. B. Ghosn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA