Heterotypic CAF-tumor spheroids promote early peritoneal metastatis of ovarian cancer

Pancreatic and bile duct cancer circulating tumor cells (CTC) form immune-resistant multi-cell type clusters in the portal venous circulation

(2018) J Pablo Arnoletti et al.   CANCER BIOLOGY & THERAPY

Fibroblast recruitment as a tool for ovarian cancer detection and targeted therapy

(2016) Roni Oren et al.   INTERNATIONAL JOURNAL OF CANCER

Tumor-associated macrophages drive spheroid formation during early transcoelomic metastasis of ovarian cancer

(2016) Mingzhu Yin et al.   JOURNAL OF CLINICAL INVESTIGATION

MENA Promotes Tumor-Intrinsic Metastasis through ECM Remodeling and Haptotaxis

(2016) M. Santiago-Medina et al.   Cancer Discovery

Low-grade serous carcinoma: molecular features and contemporary treatment strategies

(2015) Ana M Angarita et al.   Expert Review of Anticancer Therapy

Ovarian high-grade serous carcinoma with a noninvasive growth pattern simulating a serous borderline tumor

(2015) Hiroko Imamura et al.   HUMAN PATHOLOGY

CHMP5 controls bone turnover rates by dampening NF-κB activity in osteoclasts

(2015) Matthew B. Greenblatt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cancer-Associated Fibroblasts Induce a Collagen Cross-link Switch in Tumor Stroma

(2015) D. Pankova et al.   MOLECULAR CANCER RESEARCH

Assessment of selected cytokines, proteins, and growth factors in the peritoneal fluid of patients with ovarian cancer and benign gynecological conditions

(2015) Anita Chudecka-Glaz et al.   OncoTargets and Therapy

The ZNF304-integrin axis protects against anoikis in cancer

(2015) Burcu Aslan et al.   Nature Communications

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy

(2015) Hilary A. Kenny et al.   Nature Communications

Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis

(2015) Chi-Ruei Huang et al.   Oncotarget

SIX1 Promotes Tumor Lymphangiogenesis by Coordinating TGF  Signals That Increase Expression of VEGF-C

(2014) D. Liu et al.   CANCER RESEARCH

Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion

(2014) Hilary A. Kenny et al.   JOURNAL OF CLINICAL INVESTIGATION

Prognostic and Therapeutic Relevance of Molecular Subtypes in High-Grade Serous Ovarian Cancer

(2014) Gottfried E. Konecny et al.   JNCI-Journal of the National Cancer Institute

Resolving cancer–stroma interfacial signalling and interventions with micropatterned tumour–stromal assays

(2014) Keyue Shen et al.   Nature Communications

Cancer-associated fibroblasts regulate the plasticity of lung cancer stemness via paracrine signalling

(2014) Wan-Jiun Chen et al.   Nature Communications

Origin and Pathogenesis of Pelvic (Ovarian, Tubal, and Primary Peritoneal) Serous Carcinoma

(2013) Niloofar N. Nik et al.   Annual Review of Pathology-Mechanisms of Disease

Ovarian cancer microenvironment: implications for cancer dissemination and chemoresistance acquisition

(2013) Benoît Thibault et al.   CANCER AND METASTASIS REVIEWS

Survivin promotion of melanoma metastasis requires upregulation of α 5 integrin

(2013) Jodi A. McKenzie et al.   CARCINOGENESIS

Increased expression of α5β1-integrin is a prognostic marker for patients with gastric cancer

(2013) J. Ren et al.   Clinical & Translational Oncology

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules

(2013) I. Rizvi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Getting to Know Ovarian Cancer Ascites: Opportunities for Targeted Therapy-Based Translational Research

(2013) Nuzhat Ahmed et al.   Frontiers in Oncology

Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites

(2012) My Wintzell et al.   BMC CANCER

Ovarian low-grade serous carcinoma: A comprehensive update

(2012) Ivan Diaz-Padilla et al.   GYNECOLOGIC ONCOLOGY

TGF-β upregulates miR-181a expression to promote breast cancer metastasis

(2012) Molly A. Taylor et al.   JOURNAL OF CLINICAL INVESTIGATION

Isolation and Characterization of Tumor Cells from the Ascites of Ovarian Cancer Patients: Molecular Phenotype of Chemoresistant Ovarian Tumors

(2012) Ardian Latifi et al.   PLoS One

Prognostic significance of IL-6 and IL-8 ascites levels in ovarian cancer patients

(2011) Denis Lane et al.   BMC CANCER

HB-EGF and PDGF Mediate Reciprocal Interactions of Carcinoma Cells with Cancer-Associated Fibroblasts to Support Progression of Uterine Cervical Cancers

(2011) T. Murata et al.   CANCER RESEARCH

Modelling genetic and clinical heterogeneity in epithelial ovarian cancers

(2011) Kate Lawrenson et al.   CARCINOGENESIS

A phase II, single-arm study of the anti-α5β1 integrin antibody volociximab as monotherapy in patients with platinum-resistant advanced epithelial ovarian or primary peritoneal cancer

(2011) Katherine M. Bell-McGuinn et al.   GYNECOLOGIC ONCOLOGY

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth

(2011) Kristin M Nieman et al.   NATURE MEDICINE

The First Line of Intra-abdominal Metastatic Attack: Breaching the Mesothelial Cell Layer: Figure 1.

(2011) Hilary A. Kenny et al.   Cancer Discovery

Ovarian Cancer Development and Metastasis

(2010) Ernst Lengyel   AMERICAN JOURNAL OF PATHOLOGY

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-κB-Dependent Manner

(2010) Neta Erez et al.   CANCER CELL

Loss of Integrin α3 Expression is Associated with Acquisition of Invasive Potential by Ovarian Clear Cell Adenocarcinoma Cells.

(2010) Nao SUZUKI et al.   Human Cell

Ligand-independent activation of c-Met by fibronectin and α5β1-integrin regulates ovarian cancer invasion and metastasis

(2010) A K Mitra et al.   ONCOGENE

Malignant cells facilitate lung metastasis by bringing their own soil

(2010) D. G. Duda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly

(2009) H. J. Kim et al.   GENOME RESEARCH

Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

(2009) Young Kim et al.   JOURNAL OF CELL BIOLOGY

PAX2 expression in low malignant potential ovarian tumors and low-grade ovarian serous carcinomas

(2009) Celestine S Tung et al.   MODERN PATHOLOGY

Imatinib mesylate in combination with docetaxel for the treatment of patients with advanced, platinum-resistant ovarian cancer and primary peritoneal carcinomatosis

(2008) Daniela Matei et al.   CANCER

Loss of E-Cadherin Promotes Ovarian Cancer Metastasis via  5-Integrin, which Is a Therapeutic Target

(2008) K. Sawada et al.   CANCER RESEARCH

Volociximab, a Chimeric Monoclonal Antibody that Specifically Binds  5 1 Integrin: A Phase I, Pharmacokinetic, and Biological Correlative Study

(2008) A. D. Ricart et al.   CLINICAL CANCER RESEARCH

Compact spheroid formation by ovarian cancer cells is associated with contractile behavior and an invasive phenotype

(2008) Katharine L. Sodek et al.   INTERNATIONAL JOURNAL OF CANCER

Mammalian Target of Rapamycin Contributes to the Acquired Apoptotic Resistance of Human Mesothelioma Multicellular Spheroids

(2008) Dario Barbone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Low-grade serous ovarian cancer: a unique disease

(2008) Kathleen M. Schmeler et al.   Current Oncology Reports