Overexpression of Bruton Tyrosine Kinase Inhibits the Proliferation, Migration, and Invasion of Non-Small Cell Lung Cancer Cells

Immunotherapy in Lung Cancer: Current Landscape and Future Directions

(2022) Hirva Mamdani et al.   Frontiers in Immunology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2021) Hyuna Sung et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Bruton's agammaglobulinemia tyrosine kinase (Btk) regulates TPA‑induced breast cancer cell invasion via PLCγ2/PKCβ/NF‑κB/AP‑1‑dependent matrix metalloproteinase‑9 activation

(2021) Jeong-Mi Kim et al.   ONCOLOGY REPORTS

Comparative Analysis of BTK Inhibitors and Mechanisms Underlying Adverse Effects

(2021) H. Yesid Estupiñán et al.   Frontiers in Cell and Developmental Biology

Bruton’s tyrosine kinase: an emerging targeted therapy in myeloid cells within the tumor microenvironment

(2021) Logan Good et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Targeting BTK Signaling in the Microenvironment of Solid Tumors as a Feasible Cancer Therapy Option

(2021) Justin K. Messex et al.   Cancers

Current and Future Development in Lung Cancer Diagnosis

(2021) Reem Nooreldeen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Recent Advances in BTK Inhibitors for the Treatment of Inflammatory and Autoimmune Diseases

(2021) Datong Zhang et al.   MOLECULES

Impaired B Cell Apoptosis Results in Autoimmunity That Is Alleviated by Ablation of Btk

(2021) Jacqueline A. Wright et al.   Frontiers in Immunology

BTK Has Potential to Be a Prognostic Factor for Lung Adenocarcinoma and an Indicator for Tumor Microenvironment Remodeling: A Study Based on TCGA Data Mining

(2020) Ke-Wei Bi et al.   Frontiers in Oncology

BTK/ITK dual inhibitors: Modulating immunopathology and lymphopenia for COVID‐19 therapy

(2020) Michael C. McGee et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Development of BTK inhibitors for the treatment of B-cell malignancies

(2019) Hyung-Ook Kim   ARCHIVES OF PHARMACAL RESEARCH

p65BTK is a novel potential actionable target in KRAS-mutated/EGFR-wild type lung adenocarcinoma

(2019) Federica Giordano et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Role of Bruton’s tyrosine kinase in B cells and malignancies

(2018) Simar Pal Singh et al.   Molecular Cancer

BTK: a two-faced effector in cancer and tumour suppression

(2018) Miran Rada et al.   Cell Death & Disease

Lung cancer: current therapies and new targeted treatments

(2017) Fred R Hirsch et al.   LANCET

A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation

(2016) E Grassilli et al.   ONCOGENE

Ibrutinib targets mutant-EGFR kinase with a distinct binding conformation

(2016) Aoli Wang et al.   Oncotarget

A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis

(2013) Cheryl Eifert et al.   GENES CHROMOSOMES & CANCER

BTK inhibition targets in vivo CLL proliferation through its effects on B-cell receptor signaling activity

(2013) S Cheng et al.   LEUKEMIA

Bruton's Tyrosine Kinase Regulates Shigella flexneri Dissemination in HT-29 Intestinal Cells

(2012) Ana-Maria Dragoi et al.   INFECTION AND IMMUNITY

The Role of Tec Family Kinases in the Regulation of T-helper-cell Differentiation

(2012) Nicole Boucheron et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Bruton Tyrosine Kinase (BTK) and Its Role in B-cell Malignancy

(2012) Joseph J. Buggy et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

TEC family kinases in health and disease - loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK

(2011) Alamdar Hussain et al.   FEBS Journal

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

(2010) L. A. Honigberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bruton's Tyrosine Kinase Revealed as a Negative Regulator of Wnt- -Catenin Signaling

(2009) R. G. James et al.   Science Signaling