A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation

RNA-binding proteins, multifaceted translational regulators in cancer

(2015) Laurence Wurth et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Translational control by oncogenic signaling pathways

(2015) Beichen Gao et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Imbruvica—next big drug in B-cell cancer—approved by FDA

(2014) Malini Guha   NATURE BIOTECHNOLOGY

A novel isoform of the B cell tyrosine kinase BTK protects breast cancer cells from apoptosis

(2013) Cheryl Eifert et al.   GENES CHROMOSOMES & CANCER

Bruton’s Tyrosine Kinase (BTK) Inhibitors in Clinical Trials

(2013) Jan A. Burger   Current Hematologic Malignancy Reports

Gene Expression Regulation by Upstream Open Reading Frames and Human Disease

(2013) Cristina Barbosa et al.   PLoS Genetics

The RAS/RAF/MEK/ERK and the PI3K/AKT signalling pathways: role in cancer pathogenesis and implications for therapeutic approaches

(2012) Antonella De Luca et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A new framework for understanding IRES-mediated translation

(2012) Anton A. Komar et al.   GENE

Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain

(2009) Abdalla J. Mohamed et al.   IMMUNOLOGICAL REVIEWS

Post-transcriptional regulation of gene expression by alternative 5′-untranslated regions in carcinogenesis

(2008) Laura Smith   BIOCHEMICAL SOCIETY TRANSACTIONS

DAP5 Promotes Cap-Independent Translation of Bcl-2 and CDK1 to Facilitate Cell Survival during Mitosis

(2008) Lea Marash et al.   MOLECULAR CELL

Physical and functional characterization of the genetic locus of IBtk, an inhibitor of Bruton's tyrosine kinase: evidence for three protein isoforms of IBtk

(2008) Carmen Spatuzza et al.   NUCLEIC ACIDS RESEARCH

Re-programming of translation following cell stress allows IRES-mediated translation to predominate

(2007) Keith A. Spriggs et al.   BIOLOGY OF THE CELL