In vitro and in vivo immune assessments of genetically‐engineered pig skin grafts in New World (squirrel) monkeys

Clinical and molecular correlation defines activity of physiological pathways in life-sustaining kidney xenotransplantation

(2023) Daniel J. Firl et al.   Nature Communications

Genetically Modified Porcine-to-Human Cardiac Xenotransplantation

(2022) Bartley P. Griffith et al.   NEW ENGLAND JOURNAL OF MEDICINE

What Have We Learned From In Vitro Studies About Pig-to-primate Organ Transplantation?

(2022) Hidetaka Hara et al.   TRANSPLANTATION

What Therapeutic Regimen Will Be Optimal for Initial Clinical Trials of Pig Organ Transplantation?

(2021) Mohamed Bikhet et al.   TRANSPLANTATION

First GM pigs for allergies. Could xenotransplants be next?

(2021) Elie Dolgin   NATURE BIOTECHNOLOGY

The Genetically Engineered Heart as a Bridge to Allotransplantation in Infants Just Around the Corner?

(2021) David C. Cleveland et al.   ANNALS OF THORACIC SURGERY

The Growth of Xenotransplanted Hearts Can Be Reduced with Growth Hormone Receptor Knockout Pig Donors

(2021) Corbin E. Goerlich et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Initial experimental experience of triple‐knockout pig red blood cells as potential sources for transfusion in alloimmunized patients with sickle cell disease

(2021) Takayuki Yamamoto et al.   TRANSFUSION

Histopathology of pig kidney grafts with/without expression of the carbohydrate Neu5Gc in immunosuppressed baboons

(2021) Jeremy B. Foote et al.   XENOTRANSPLANTATION

Vital, Porcine, Gal-Knockout Skin Transplants Provide Efficacious Temporary Closure of Full-Thickness Wounds: Good Laboratory Practice-Compliant Studies in Nonhuman Primates

(2020) Paul Holzer et al.   Journal of Burn Care & Research

Skin xenotransplantation

(2020) Richa Kalsi et al.   Current Opinion in Organ Transplantation

Immunological response in cynomolgus macaques to porcine α-1,3 galactosyltransferase knockout viable skin xenotransplants-A pre-clinical study

(2020) Paul W. Holzer et al.   XENOTRANSPLANTATION

The human T‐cell proliferative response to triple‐knockout pig cells in mixed lymphocyte reaction

(2020) Zheng‐Yu Wang et al.   XENOTRANSPLANTATION

Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

(2020) Takayuki Yamamoto et al.   Scientific Reports

Carbohydrate antigen expression and anti-pig antibodies in New World capuchin monkeys: Relevance to studies of xenotransplantation

(2019) Qi Li et al.   XENOTRANSPLANTATION

Justification of specific genetic modifications in pigs for clinical organ xenotransplantation

(2019) David K. C. Cooper et al.   XENOTRANSPLANTATION

Inhibition of T Helper Cell Differentiation by Tacrolimus or Sirolimus Results in Reduced B-Cell Activation: Effects on T Follicular Helper Cells

(2019) Rens Kraaijeveld et al.   TRANSPLANTATION PROCEEDINGS

Skin xenotransplantation: Historical review and clinical potential

(2018) Takayuki Yamamoto et al.   BURNS

Xenoantigen Deletion and Chemical Immunosuppression Can Prolong Renal Xenograft Survival

(2018) Andrew B. Adams et al.   ANNALS OF SURGERY

Prolonged Survival of Pig Skin on Baboons After Administration of Pig Cells Expressing Human CD47

(2017) Aseda A. Tena et al.   TRANSPLANTATION

Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

Genetically modified porcine split-thickness skin grafts as an alternative to allograft for provision of temporary wound coverage: preliminary characterization

(2015) Angelo A. Leto Barone et al.   BURNS

Initial in vivo experience of pig artery patch transplantation in baboons using mutant MHC (CIITA-DN) pigs

(2015) H. Iwase et al.   TRANSPLANT IMMUNOLOGY

Transgenic expression of human CD46: does it reduce the primate T-cell response to pig endothelial cells?

(2015) Mohamed B Ezzelarab et al.   XENOTRANSPLANTATION

Evaluation of human and non-human primate antibody binding to pig cells lacking GGTA1/CMAH/β4GalNT2 genes

(2015) Jose L. Estrada et al.   XENOTRANSPLANTATION

Functional Characterization of Human T Cell Hyporesponsiveness Induced by CTLA4-Ig

(2015) Yrina Rochman et al.   PLoS One

Creating Class I MHC–Null Pigs Using Guide RNA and the Cas9 Endonuclease

(2014) Luz M. Reyes et al.   JOURNAL OF IMMUNOLOGY

Transgenic expression of human cytoxic T-lymphocyte associated antigen4-Immunoglobulin (hCTLA4Ig) by porcine skin for xenogeneic skin grafting

(2014) Yong Wang et al.   TRANSGENIC RESEARCH

Lack of Cross-Sensitization Between α-1,3-Galactosyltransferase Knockout Porcine and Allogeneic Skin Grafts Permits Serial Grafting

(2014) Alexander Albritton et al.   TRANSPLANTATION

Effect of FK506 Ointment (Protopic) on Rat Skin Allograft Model

(2014) Y.E. Kim et al.   TRANSPLANTATION PROCEEDINGS

Pig to rat cell transplantation: reduced cellular and antibody responses to xenografts overexpressing PD-L1

(2014) Annegret Plege-Fleck et al.   XENOTRANSPLANTATION

Cloning and expression of porcine β1,4 N-acetylgalactosaminyl transferase encoding a new xenoreactive antigen

(2014) Guerard W. Byrne et al.   XENOTRANSPLANTATION

Human dominant-negative class II transactivator transgenic pigs - effect on the human anti-pig T-cell immune response and immune status

(2013) Hidetaka Hara et al.   IMMUNOLOGY

American Burn Association Consensus Statements

(2013) Nicole S. Gibran et al.   Journal of Burn Care & Research

The immunosuppressive molecule HLA-G and its clinical implications

(2012) Ãlvaro González et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Preservation methods of allografts and their (lack of) influence on clinical results in partial thickness burns

(2011) Michel H.E. Hermans   BURNS

Immune recognition and rejection of allogeneic skin grafts

(2011) Gilles Benichou et al.   Immunotherapy

Prolonged survival of GalT-KO swine skin on baboons

(2010) Joshua Weiner et al.   XENOTRANSPLANTATION

Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help

(2009) S. Heidt et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

HLA-E/Human β2-Microglobulin Transgenic Pigs: Protection Against Xenogeneic Human Anti-Pig Natural Killer Cell Cytotoxicity

(2009) Elisabeth H. Weiss et al.   TRANSPLANTATION

Production and characterization of transgenic pigs expressing porcine CTLA4-Ig

(2009) Carol J. Phelps et al.   XENOTRANSPLANTATION

The Banff 2007 Working Classification of Skin-Containing Composite Tissue Allograft Pathology

(2008) L. C Cendales et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Mortality and causes of death in a burn centre

(2008) G.C. Bloemsma et al.   BURNS

NK cells contribute to the skin graft rejection promoted by CD4+ T cells activated through the indirect allorecognition pathway

(2008) Akiko Ito et al.   INTERNATIONAL IMMUNOLOGY