Immunological and physiological observations in baboons with life-supporting genetically engineered pig kidney grafts

Therapeutic regulation of systemic inflammation in xenograft recipients

(2017) Hayato Iwase et al.   XENOTRANSPLANTATION

Role of TLRs and DAMPs in allograft inflammation and transplant outcomes

(2016) Faouzi Braza et al.   Nature Reviews Nephrology

Anti-TNF-α Agent Infliximab and Splenectomy Are Protective Against Renal Ischemia-Reperfusion Injury

(2016) Yudai Nagata et al.   TRANSPLANTATION

A Nonhematopoietic Erythropoietin Analogue, ARA 290, Inhibits Macrophage Activation and Prevents Damage to Transplanted Islets

(2016) Masaaki Watanabe et al.   TRANSPLANTATION

Thyroid hormone: relevance to xenotransplantation

(2016) Hayato Iwase et al.   XENOTRANSPLANTATION

Further evidence for sustained systemic inflammation in xenograft recipients (SIXR)

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Pig kidney graft survival in a baboon for 136 days: longest life-supporting organ graft survival to date

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Pig-to-baboon heterotopic heart transplantation - exploratory preliminary experience with pigs transgenic for human thrombomodulin and comparison of three costimulation blockade-based regimens

(2015) Hayato Iwase et al.   XENOTRANSPLANTATION

Pre-transplant antibody screening and anti-CD154 costimulation blockade promote long-term xenograft survival in a pig-to-primate kidney transplant model

(2015) Laura Higginbotham et al.   XENOTRANSPLANTATION

Current status of pig kidney xenotransplantation

(2015) Hayato Iwase et al.   International Journal of Surgery

Systemic inflammation in xenograft recipients (SIXR): A new paradigm in pig-to-primate xenotransplantation?

(2015) Mohamed B. Ezzelarab et al.   International Journal of Surgery

Immune Modulation in Xenotransplantation

(2014) Magdalena Boksa et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Inflammatory triggers of acute rejection of organ allografts

(2014) Daniel N. Mori et al.   IMMUNOLOGICAL REVIEWS

Immunosuppressive Effects of Erythropoietin on Human Alloreactive T Cells

(2014) P. Cravedi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

When Erythropoietin Meddles in Immune Affairs

(2014) F. Martinez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Porcine Cytomegalovirus Infection Is Associated With Early Rejection of Kidney Grafts in a Pig to Baboon Xenotransplantation Model

(2014) Kazuhiko Yamada et al.   TRANSPLANTATION

Meta-analysis of the independent and cumulative effects of multiple genetic modifications on pig lung xenograft performance during ex vivo perfusion with human blood

(2014) Donald G. Harris et al.   XENOTRANSPLANTATION

Systemic inflammation in xenograft recipients precedes activation of coagulation

(2014) Mohamed B. Ezzelarab et al.   XENOTRANSPLANTATION

Plasma free triiodothyronine (fT3) levels in baboons undergoing pig organ transplantation: relevance to early recovery of organ function

(2014) Hayato Iwase et al.   XENOTRANSPLANTATION

Progress in pig-to-non-human primate transplantation models (1998-2013): a comprehensive review of the literature

(2014) David K. C. Cooper et al.   XENOTRANSPLANTATION

Are there advantages in the use of specific pathogen-free baboons in pig organ xenotransplantation models?

(2014) Huidong Zhou et al.   XENOTRANSPLANTATION

Regulatory Dendritic Cell Infusion Prolongs Kidney Allograft Survival in Nonhuman Primates

(2013) M. B. Ezzelarab et al.   AMERICAN JOURNAL OF TRANSPLANTATION

One-Year Heterotopic Cardiac Xenograft Survival in a Pig to Baboon Model

(2013) M. M. Mohiuddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Regulatory Sequences of the Porcine THBD Gene Facilitate Endothelial-Specific Expression of Bioactive Human Thrombomodulin in Single- and Multitransgenic Pigs

(2013) Annegret Wuensch et al.   TRANSPLANTATION

Role of anti-CD40 antibody-mediated costimulation blockade on non-Gal antibody production and heterotopic cardiac xenograft survival in a GTKO.hCD46Tg pig-to-baboon model

(2013) Muhammad M. Mohiuddin et al.   XENOTRANSPLANTATION

A Novel Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival

(2012) M. Lowe et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Safety and tolerability of the T-cell depletion protocol coupled with anakinra and etanercept for clinical islet cell transplantation

(2012) Morihito Takita et al.   CLINICAL TRANSPLANTATION

Genetically-Engineered Pig-to-Baboon Liver Xenotransplantation: Histopathology of Xenografts and Native Organs

(2012) Burcin Ekser et al.   PLoS One

Human CD55 Expression Blocks Hyperacute Rejection and Restricts Complement Activation in Gal Knockout Cardiac Xenografts

(2012) Christopher G.A. McGregor et al.   TRANSPLANTATION

Clinical lung xenotransplantation - what donor genetic modifications may be necessary?

(2012) David K. C. Cooper et al.   XENOTRANSPLANTATION

Comparison of hematologic, biochemical, and coagulation parameters in α1,3-galactosyltransferase gene-knockout pigs, wild-type pigs, and four primate species

(2012) Burcin Ekser et al.   XENOTRANSPLANTATION

Costimulation blockade in pig artery patch xenotransplantation - a simple model to monitor the adaptive immune response in nonhuman primates

(2012) Mohamed B. Ezzelarab et al.   XENOTRANSPLANTATION

Islet Xenotransplantation Using Gal-Deficient Neonatal Donors Improves Engraftment and Function

(2011) P. Thompson et al.   AMERICAN JOURNAL OF TRANSPLANTATION

B-Cell Depletion Extends the Survival of GTKO.hCD46Tg Pig Heart Xenografts in Baboons for up to 8 Months

(2011) M. M. Mohiuddin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Improving Efficacy of Clinical Islet Transplantation with Iodixanol-Based Islet Purification, Thymoglobulin Induction, and Blockage of IL-1β and TNF-α

(2011) Shinichi Matsumoto et al.   CELL TRANSPLANTATION

The 5-Year Outcome of ABO-Incompatible Kidney Transplantation With Rituximab Induction

(2011) Shohei Fuchinoue et al.   TRANSPLANTATION

Changes in cardiac gene expression after pig-to-primate orthotopic xenotransplantation

(2011) Guerard W. Byrne et al.   XENOTRANSPLANTATION

Recipient Tissue Factor Expression Is Associated With Consumptive Coagulopathy in Pig-to-Primate Kidney Xenotransplantation

(2010) C. C. Lin et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Renal and Cardiac Endothelial Heterogeneity Impact Acute Vascular Rejection in Pig-to-Baboon Xenotransplantation

(2009) C. Knosalla et al.   AMERICAN JOURNAL OF TRANSPLANTATION

The Innate Immune Response and Activation of Coagulation in α1,3-Galactosyltransferase Gene-Knockout Xenograft Recipients

(2009) Mohamed Ezzelarab et al.   TRANSPLANTATION