Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease

The β8 integrin cytoplasmic domain activates extracellular matrix adhesion to promote brain neurovascular development

(2022) Arpan De et al.   DEVELOPMENT

Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration

(2022) Amrendra K. Ajay et al.   Cell Reports

MicroRNA-10a/b inhibit TGF-β/Smad-induced renal fibrosis by targeting TGF-β receptor 1 in diabetic kidney disease

(2022) Jinxiang Li et al.   Molecular Therapy-Nucleic Acids

Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma

(2022) Yang Liu et al.   Cell Death & Disease

New strategies to improve clinical outcomes for diabetic kidney disease

(2022) Thomas Forst et al.   BMC Medicine

US Renal Data System 2020 Annual Data Report: Epidemiology of Kidney Disease in the United States

(2021) Kirsten L. Johansen et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

KIM-1 mediates fatty acid uptake by renal tubular cells to promote progressive diabetic kidney disease

(2021) Yutaro Mori et al.   Cell Metabolism

TGF-Beta as a Master Regulator of Diabetic Nephropathy

(2021) Li Wang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diabetic Complications: An Update on Pathobiology and Therapeutic Strategies

(2021) Karthika Nellaiappan et al.   CURRENT DIABETES REVIEWS

Methylation in pericytes after acute injury promotes chronic kidney disease

(2020) Yu-Hsiang Chou et al.   JOURNAL OF CLINICAL INVESTIGATION

Putative endothelial progenitor cells do not promote vascular repair but attenuate pericyte–myofibroblast transition in UUO-induced renal fibrosis

(2019) Juan Yang et al.   Stem Cell Research & Therapy

Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low‐dose cisplatin exposure

(2019) Hua Su et al.   FASEB JOURNAL

Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2

(2018) Fang-Fang He et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

CKD in diabetes: diabetic kidney disease versus nondiabetic kidney disease

(2018) Hans-Joachim Anders et al.   Nature Reviews Nephrology

MDM2 is implicated in high-glucose-induced podocyte mitotic catastrophe via Notch1 signalling

(2017) Hui Tang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation

(2017) Nan Wang et al.   Scientific Reports

MDM2 Contributes to High Glucose-Induced Glomerular Mesangial Cell Proliferation and Extracellular Matrix Accumulation via Notch1

(2017) Chun-Tao Lei et al.   Scientific Reports

Activation of the Pro-Oxidant PKCβII-p66ShcSignaling Pathway Contributes to Pericyte Dysfunction in Skeletal Muscles of Patients With Diabetes With Critical Limb Ischemia

(2016) Rosa Vono et al.   DIABETES

Anti–TGF-β1 Antibody Therapy in Patients with Diabetic Nephropathy

(2016) James Voelker et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice

(2016) Li Ma et al.   Translational Stroke Research

Peroxisome Proliferator–Activated Receptor α Protects Capillary Pericytes in the Retina

(2014) Lexi Ding et al.   AMERICAN JOURNAL OF PATHOLOGY

Epigenetic mechanisms in diabetic complications and metabolic memory

(2014) Marpadga A. Reddy et al.   DIABETOLOGIA

Structural determinants of integrin β-subunit specificity for latent TGF-β

(2014) Xianchi Dong et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Erratum to: Renal pericytes: multifunctional cells of the kidneys

(2013) Ania Stefańska et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Renal Endothelium in Diabetic Nephropathy

(2013) Theodoros Eleftheriadis et al.   RENAL FAILURE

Pericyte TIMP3 and ADAMTS1 Modulate Vascular Stability after Kidney Injury

(2012) C. Schrimpf et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Targeting Pericyte Differentiation as a Strategy to Modulate Kidney Fibrosis in Diabetic Nephropathy

(2012) Benjamin D. Humphreys   SEMINARS IN NEPHROLOGY

Mesangial Cell Integrin αvβ8 Provides Glomerular Endothelial Cell Cytoprotection by Sequestering TGF-β and Regulating PECAM-1

(2011) Shenaz Khan et al.   AMERICAN JOURNAL OF PATHOLOGY

Mechanisms of fibrosis: the role of the pericyte

(2011) Claudia Schrimpf et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Platelet-derived growth factor receptor signaling activates pericyte–myofibroblast transition in obstructive and post-ischemic kidney fibrosis

(2011) Yi-Ting Chen et al.   KIDNEY INTERNATIONAL

Integrin Structure, Activation, and Interactions

(2011) I. D. Campbell et al.   Cold Spring Harbor Perspectives in Biology

Origin of new cells in the adult kidney: results from genetic labeling techniques

(2010) Jeremy S. Duffield et al.   KIDNEY INTERNATIONAL

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

The Mesangial Cell Revisited: No Cell Is an Island

(2009) D. Schlondorff et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Pericytes and Perivascular Fibroblasts Are the Primary Source of Collagen-Producing Cells in Obstructive Fibrosis of the Kidney

(2008) Shuei-Liong Lin et al.   AMERICAN JOURNAL OF PATHOLOGY