Paradoxical role of β8 integrin on angiogenesis and vasculogenic mimicry in glioblastoma

Mechanisms of vasculogenic mimicry in hypoxic tumor microenvironments

(2021) Xiaoxu Wei et al.   Molecular Cancer

The Great Escape: The Power of Cancer Stem Cells to Evade Programmed Cell Death

(2021) Vanessa Castelli et al.   Cancers

lncRNA ITGB8-AS1 functions as a ceRNA to promote colorectal cancer growth and migration through integrin-mediated focal adhesion signaling

(2021) Xiaoting Lin et al.   MOLECULAR THERAPY

The prognostic value of ITGA and ITGB superfamily members in patients with high grade serous ovarian cancer

(2020) Tingting Zhu et al.   Cancer Cell International

Transforming Growth Factor-β Signaling in Immunity and Cancer

(2019) Eduard Batlle et al.   IMMUNITY

Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis

(2019) Chen Wei et al.   Molecular Cancer

β8 integrin mediates pancreatic cancer cell radiochemoresistance

(2019) Sha Jin et al.   MOLECULAR CANCER RESEARCH

EMT, stemness and tumor plasticity in aggressive variant neuroendocrine prostate cancers

(2018) Rama Soundararajan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Cancer stem cell in breast cancer therapeutic resistance

(2018) Xupeng Bai et al.   CANCER TREATMENT REVIEWS

IDH mutation status is associated with distinct vascular gene expression signatures in lower-grade gliomas

(2018) Lei Zhang et al.   NEURO-ONCOLOGY

IGFBP2 promotes vasculogenic mimicry formation via regulating CD144 and MMP2 expression in glioma

(2018) Y. Liu et al.   ONCOGENE

Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression

(2017) P A Guerrero et al.   ONCOGENE

Ubiquitin-dependent regulation of Cdc42 by XIAP

(2017) Arun Murali et al.   Cell Death & Disease

COL11A1 is overexpressed in gastric cancer tissues and regulates proliferation, migration and invasion of HGC-27 gastric cancer cells in vitro

(2016) Aiqing Li et al.   ONCOLOGY REPORTS

The tumour-promoting receptor tyrosine kinase, EphB4, regulates expression of Integrin-β8 in prostate cancer cells

(2015) Inga Mertens-Walker et al.   BMC CANCER

Tumor Stroma, Tumor Blood Vessels, and Antiangiogenesis Therapy

(2015) Harold F. Dvorak   CANCER JOURNAL

Hypoxia promotes vasculogenic mimicry formation by inducing epithelial–mesenchymal transition in ovarian carcinoma

(2014) Jing Du et al.   GYNECOLOGIC ONCOLOGY

Release of Active TGF-β1 from the Latent TGF-β1/GARP Complex on T Regulatory Cells Is Mediated by Integrin β8

(2014) Justin P. Edwards et al.   JOURNAL OF IMMUNOLOGY

αvβ8 integrin interacts with RhoGDI1 to regulate Rac1 and Cdc42 activation and drive glioblastoma cell invasion

(2013) Steve B. Reyes et al.   MOLECULAR BIOLOGY OF THE CELL

Molecular Pathways: Vasculogenic Mimicry in Tumor Cells: Diagnostic and Therapeutic Implications

(2012) D. A. Kirschmann et al.   CLINICAL CANCER RESEARCH

Glioblastoma-derived Tumor Cells Induce Vasculogenic Mimicry through Flk-1 Protein Activation

(2012) Ralph Francescone et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transdifferentiation of Glioblastoma Stem-Like Cells into Mural Cells Drives Vasculogenic Mimicry in Glioblastomas

(2012) S. Scully et al.   JOURNAL OF NEUROSCIENCE

Defective Retinal Vascular Endothelial Cell Development As a Consequence of Impaired Integrin  V 8-Mediated Activation of Transforming Growth Factor- 

(2012) T. D. Arnold et al.   JOURNAL OF NEUROSCIENCE

β8 integrin is essential for neuroblast migration in the rostral migratory stream

(2011) Aaron K. Mobley et al.   GLIA

Latent TGF-β structure and activation

(2011) Minlong Shi et al.   NATURE

A new alternative mechanism in glioblastoma vascularization: tubular vasculogenic mimicry

(2010) S. El Hallani et al.   BRAIN

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

Transcription of the Transforming Growth Factor β Activating Integrin β8 Subunit Is Regulated by SP3, AP-1, and the p38 Pathway

(2010) Jennifer A. Markovics et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Study of Bevacizumab Plus Temozolomide During and After Radiation Therapy for Patients With Newly Diagnosed Glioblastoma Multiforme

(2010) Albert Lai et al.   JOURNAL OF CLINICAL ONCOLOGY

The proliferation, apoptosis, invasion of endothelial-like epithelial ovarian cancer cells induced by hypoxia

(2010) Pengfei Zhu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells

(2010) Lucia Ricci-Vitiani et al.   NATURE

Glioblastoma stem-like cells give rise to tumour endothelium

(2010) Rong Wang et al.   NATURE

MicroRNA miR-93 promotes tumor growth and angiogenesis by targeting integrin-β8

(2010) L Fang et al.   ONCOGENE

Establishing Intracranial Brain Tumor Xenografts With Subsequent Analysis of Tumor Growth and Response to Therapy using Bioluminescence Imaging

(2010) Tomoko Ozawa et al.   Jove-Journal of Visualized Experiments

 8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain

(2009) A. K. Mobley et al.   JOURNAL OF CELL SCIENCE

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Non-Smad pathways in TGF-β signaling

(2008) Ying E Zhang   CELL RESEARCH

An exploratory survival analysis of anti-angiogenic therapy for recurrent malignant glioma

(2008) Andrew D. Norden et al.   JOURNAL OF NEURO-ONCOLOGY