Integrin β8 Deletion Enhances Vascular Dysplasia and Hemorrhage in the Brain of Adult Alk1 Heterozygous Mice

Hemorrhage Rates From Brain Arteriovenous Malformation in Patients With Hereditary Hemorrhagic Telangiectasia

(2015) H. Kim et al.   STROKE

Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking  V 8-TGF  signaling in the brain

(2014) T. D. Arnold et al.   DEVELOPMENT

Novel Brain Arteriovenous Malformation Mouse Models for Type 1 Hereditary Hemorrhagic Telangiectasia

(2014) Eun-Jung Choi et al.   PLoS One

De Novo Cerebrovascular Malformation in the Adult Mouse After Endothelial Alk1 Deletion and Angiogenic Stimulation

(2014) Wanqiu Chen et al.   STROKE

Hemorrhage Rates and Risk Factors in the Natural History Course of Brain Arteriovenous Malformations

(2014) W. Caleb Rutledge et al.   Translational Stroke Research

Brain Arteriovenous Malformation Modeling, Pathogenesis, and Novel Therapeutic Targets

(2014) Wanqiu Chen et al.   Translational Stroke Research

Endoglin Deficiency in Bone Marrow is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse After Vascular Endothelial Growth Factor Stimulation

(2013) Eun-Jung Choi et al.   STROKE

Reduced Mural Cell Coverage and Impaired Vessel Integrity After Angiogenic Stimulation in the Alk1 -deficient Brain

(2012) Wanqiu Chen et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Minimal Homozygous Endothelial Deletion of Eng with VEGF Stimulation Is Sufficient to Cause Cerebrovascular Dysplasia in the Adult Mouse

(2012) Eun-Jung Choi et al.   CEREBROVASCULAR DISEASES

Age-Dependent Lethality in Novel Transgenic Mouse Models of Central Nervous System Arteriovenous Malformations

(2012) Ian Milton et al.   STROKE

Polymorphisms in ACVRL1 and Endoglin Genes are Not Associated with Sporadic and HHT-Related Brain AVMs in Dutch Patients

(2012) Kim Boshuisen et al.   Translational Stroke Research

Arteriovenous malformation in the adult mouse brain resembling the human disease

(2010) Espen J. Walker et al.   ANNALS OF NEUROLOGY

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

(2010) Marwa Mahmoud et al.   CIRCULATION RESEARCH

VEGF Induces More Severe Cerebrovascular Dysplasia in Eng+/− than in Alk1+/− Mice

(2010) Qi Hao et al.   Translational Stroke Research

Reduced Expression of Integrin αvβ8 Is Associated with Brain Arteriovenous Malformation Pathogenesis

(2009) Hua Su et al.   AMERICAN JOURNAL OF PATHOLOGY

 8 integrin regulates neurogenesis and neurovascular homeostasis in the adult brain

(2009) A. K. Mobley et al.   JOURNAL OF CELL SCIENCE

Increased tissue perfusion promotes capillary dysplasia in the ALK1-deficient mouse brain following VEGF stimulation

(2008) Qi Hao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

ALK5- and TGFBR2-independent role of ALK1 in the pathogenesis of hereditary hemorrhagic telangiectasia type 2

(2007) S. O. Park et al.   BLOOD