STING signaling in islet macrophages impairs insulin secretion in obesity
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
STING signaling in islet macrophages impairs insulin secretion in obesity
Authors
Keywords
-
Journal
Science China-Life Sciences
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-31
DOI
10.1007/s11427-022-2371-9
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses
- (2022) Isabelle K. Vila et al. Cell Metabolism
- A distinct role of STING in regulating glucose homeostasis through insulin sensitivity and insulin secretion
- (2022) Jingting Qiao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Intervention of cGAS‒STING signaling in sterile inflammatory diseases
- (2022) Ze Hong et al. Journal of Molecular Cell Biology
- Bcl10 phosphorylation-dependent droplet-like condensation positively regulates DNA virus-induced innate immune signaling
- (2022) Dandan Yang et al. Science China-Life Sciences
- cGAS‐STING pathway: post‐translational modifications and functions in sterile inflammatory diseases
- (2021) Ze Hong et al. FEBS Journal
- STING inhibitors target the cyclic dinucleotide binding pocket
- (2021) Ze Hong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Global Proteomic Analyses of STING‐Positive and ‐Negative Macrophages Reveal STING and Non‐STING Differentially Regulated Cellular and Molecular Pathways
- (2020) Uma K. Aryal et al. Proteomics Clinical Applications
- Secretory Functions of Macrophages in the Human Pancreatic Islet Are Regulated by Endogenous Purinergic Signaling
- (2020) Jonathan R. Weitz et al. DIABETES
- TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
- (2020) Katherine R. Balka et al. Cell Reports
- TLR4 signals through islet macrophages to alter cytokine secretion during diabetes
- (2020) Manesh Chittezhath et al. JOURNAL OF ENDOCRINOLOGY
- The STING-IRF3 pathway is involved in lipotoxic injury of pancreatic β cells in type 2 diabetes
- (2020) H.Q. Hu et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Mitochondrial stress-activated cGAS-STING pathway inhibits thermogenic program and contributes to overnutrition-induced obesity in mice
- (2020) Juli Bai et al. Communications Biology
- Metabolism-Associated Molecular Patterns (MAMPs)
- (2020) Xu Wang et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
- (2020) Shufang Cui et al. Cell Reports
- Offspring of Mice Exposed to a Low-Protein Diet in Utero Demonstrate Changes in mTOR Signaling in Pancreatic Islets of Langerhans, Associated with Altered Glucagon and Insulin Expression and a Lower β-Cell Mass
- (2019) Renee King et al. Nutrients
- Structural basis of STING binding with and phosphorylation by TBK1
- (2019) Conggang Zhang et al. NATURE
- The cGAS-cGAMP-STING Pathway: A Molecular Link Between Immunity and Metabolism
- (2019) Juli Bai et al. DIABETES
- Toll-like receptors TLR2 and TLR4 block the replication of pancreatic β cells in diet-induced obesity
- (2019) Yewei Ji et al. NATURE IMMUNOLOGY
- STING Polymer Structure Reveals Mechanisms for Activation, Hyperactivation, and Inhibition
- (2019) Sabrina L. Ergun et al. CELL
- DNA sensing by the cGAS–STING pathway in health and disease
- (2019) Mona Motwani et al. NATURE REVIEWS GENETICS
- Graph-based genome alignment and genotyping with HISAT2 and HISAT-genotype
- (2019) Daehwan Kim et al. NATURE BIOTECHNOLOGY
- A Simple High Efficiency Protocol for Pancreatic Islet Isolation from Mice
- (2019) Daniel Villarreal et al. Jove-Journal of Visualized Experiments
- The integrative biology of type 2 diabetes
- (2019) Michael Roden et al. NATURE
- The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities
- (2019) Wei Ying et al. Nature Reviews Endocrinology
- The resident macrophages in murine pancreatic islets are constantly probing their local environment, capturing beta cell granules and blood particles
- (2018) Bernd H. Zinselmeyer et al. DIABETOLOGIA
- Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
- (2018) J.T. Qiao et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Palmitic and Oleic Acid: The Yin and Yang of Fatty Acids in Type 2 Diabetes Mellitus
- (2018) Xavier Palomer et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity
- (2018) Wei Ying et al. Cell Metabolism
- Expression of STING Is Increased in Liver Tissues From Patients With NAFLD and Promotes Macrophage-Mediated Hepatic Inflammation and Fibrosis in Mice
- (2018) Xianjun Luo et al. GASTROENTEROLOGY
- STING-mediated inflammation in Kupffer cells contributes to progression of nonalcoholic steatohepatitis
- (2018) Yongsheng Yu et al. JOURNAL OF CLINICAL INVESTIGATION
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Insulin action and resistance in obesity and type 2 diabetes
- (2017) Michael P Czech NATURE MEDICINE
- DsbA-L prevents obesity-induced inflammation and insulin resistance by suppressing the mtDNA release-activated cGAS-cGAMP-STING pathway
- (2017) Juli Bai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA Sequencing of Single Human Islet Cells Reveals Type 2 Diabetes Genes
- (2016) Yurong Xin et al. Cell Metabolism
- Single-Cell Transcriptome Profiling of Human Pancreatic Islets in Health and Type 2 Diabetes
- (2016) Åsa Segerstolpe et al. Cell Metabolism
- Regulation of metabolism by the innate immune system
- (2015) Denise E. Lackey et al. Nature Reviews Endocrinology
- Beta cells transfer vesicles containing insulin to phagocytes for presentation to T cells
- (2015) Anthony N. Vomund et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TLR2/6 and TLR4-activated macrophages contribute to islet inflammation and impair beta cell insulin gene expression via IL-1 and IL-6
- (2014) Dominika Nackiewicz et al. DIABETOLOGIA
- Resident Macrophages Mediate Islet Amyloid Polypeptide–Induced Islet IL-1β Production and β-Cell Dysfunction
- (2013) Clara Y. Westwell-Roper et al. DIABETES
- Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes
- (2013) Tony Jourdan et al. NATURE MEDICINE
- STING-IRF3 pathway links endoplasmic reticulum stress with hepatocyte apoptosis in early alcoholic liver disease
- (2013) J. Petrasek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation
- (2012) Kosei Eguchi et al. Cell Metabolism
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
- (2010) J. A. Ehses et al. DIABETOLOGIA
- Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes
- (2010) Seth L Masters et al. NATURE IMMUNOLOGY
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now