Orotic acid induces apoptotic death in ovarian adult granulosa tumour cells and increases mitochondrial activity in normal ovarian granulosa cells

Hypoxia Active Platinum(IV) Prodrugs of Orotic Acid Selective to Liver Cancer Cells

(2021) Moumita Maji et al.   INORGANIC CHEMISTRY

Importance of Bioactive Substances in Sheep’s Milk in Human Health

(2021) Zuzanna Flis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Signaling Pathways in Cancer: Therapeutic Targets, Combinatorial Treatments, and New Developments

(2021) Hon Yan Kelvin Yip et al.   Cells

Prognostic significance of cyclin D3 expression in malignancy patients: a meta-analysis

(2019) Bo Wang et al.   Cancer Cell International

The molecular mechanism of ovarian granulosa cell tumors

(2018) Jiaheng Li et al.   Journal of Ovarian Research

A real-time, bioluminescent annexin V assay for the assessment of apoptosis

(2018) Kevin Kupcho et al.   APOPTOSIS

Persistent endocrine-disrupting chemicals found in human follicular fluid stimulate the proliferation of granulosa tumor spheroids via GPR30 and IGF1R but not via the classic estrogen receptors

(2018) Justyna Gogola et al.   CHEMOSPHERE

Exposure of phosphatidylserine on the cell surface

(2016) S Nagata et al.   CELL DEATH AND DIFFERENTIATION

Orotic Acid, More Than Just an Intermediate of Pyrimidine de novo Synthesis

(2015) Monika Löffler et al.   Journal of Genetics and Genomics

Targeting Apoptosis Pathways in Cancer and Perspectives with Natural Compounds from Mother Nature

(2014) F. M. Millimouno et al.   Cancer Prevention Research

The Requirement for Cyclin D Function in Tumor Maintenance

(2012) Yoon Jong Choi et al.   CANCER CELL

Establishment of a Human Nonluteinized Granulosa Cell Line that Transitions from the Gonadotropin-Independent to the Gonadotropin-Dependent Status

(2012) Bayasula et al.   ENDOCRINOLOGY

Tri- and diorganotin(IV) complexes of biologically important orotic acid: Synthesis, spectroscopic studies, in vitro anti-cancer, DNA fragmentation, enzyme assays and in vivo anti-inflammatory activities

(2012) Mala Nath et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells

(2012) Eun-Jeong Jung et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Improvement of the energy supply and contractile function in normal and ischemic rat hearts by dietary orotic acid

(2012) Laura Cristina Jardim Pôrto et al.   LIFE SCIENCES

Surgical staging and adjuvant chemotherapy in the management of patients with adult granulosa cell tumors of the ovary

(2011) Jeong-Yeol Park et al.   GYNECOLOGIC ONCOLOGY

A cyclin-D1 interaction with BAX underlies its oncogenic role and potential as a therapeutic target in mantle cell lymphoma

(2011) E. Beltran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The hydroxyl functional group of N-(4-hydroxyphenyl)retinamide mediates cellular uptake and cytotoxicity in premalignant and malignant human epithelial cells

(2010) Numsen Hail et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Role of Mitochondria in Apoptosis

(2009) Chunxin Wang et al.   Annual Review of Genetics