- Home
- Publications
- Publication Search
- Publication Details
Title
The molecular mechanism of ovarian granulosa cell tumors
Authors
Keywords
GCT, FOXL2, PI3K/AKT signaling, TGF-β signaling, Notch signaling
Journal
Journal of Ovarian Research
Volume 11, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-02-06
DOI
10.1186/s13048-018-0384-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- FSH Stimulation promotes progesterone synthesis and output from human granulosa cells without luteinization
- (2017) Ozgur Oktem et al. HUMAN REPRODUCTION
- Cell Cycle Control by PTEN
- (2017) Andrew Brandmaier et al. JOURNAL OF MOLECULAR BIOLOGY
- Abnormal expression levels of BMP15/Smad1 are associated with granulosa cell apoptosis in patients with polycystic ovary syndrome
- (2017) Xiangrong Cui et al. Molecular Medicine Reports
- Vascular endothelial growth factor (VEGF) and VEGF receptor inhibitors in the treatment of renal cell carcinomas
- (2017) Robert Roskoski PHARMACOLOGICAL RESEARCH
- Transforming Growth Factor-β Receptors and Smads: Regulatory Complexity and Functional Versatility
- (2017) Erine H. Budi et al. TRENDS IN CELL BIOLOGY
- Incidence and occupational variation of ovarian granulosa cell tumours in Finland, Iceland, Norway and Sweden during 1953-2012: a longitudinal cohort study
- (2016) S Bryk et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- Constitutive Activation of PI3K in Oocyte Induces Ovarian Granulosa Cell Tumors
- (2016) So-Youn Kim et al. CANCER RESEARCH
- Role of Notch signaling in granulosa cell proliferation and polyovular follicle induction during folliculogenesis in mouse ovary
- (2016) Karin J. Terauchi et al. CELL AND TISSUE RESEARCH
- Impact of FOXL2 mutations on signaling in ovarian granulosa cell tumors
- (2016) Dilys T.H. Leung et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Cisplatin-induced CCL5 secretion from CAFs promotes cisplatin-resistance in ovarian cancer via regulation of the STAT3 and PI3K/Akt signaling pathways
- (2016) BO ZHOU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- miR-124 Regulates the Expression of BACE1 in the Hippocampus Under Chronic Cerebral Hypoperfusion
- (2016) Xiaowen Zhang et al. MOLECULAR NEUROBIOLOGY
- Blockage of glutaminolysis enhances the sensitivity of ovarian cancer cells to PI3K/mTOR inhibition involvement of STAT3 signaling
- (2016) Lili Guo et al. TUMOR BIOLOGY
- The four and a half LIM domains 2 (FHL2) regulates ovarian granulosa cell tumor progression via controlling AKT1 transcription
- (2016) G Hua et al. Cell Death & Disease
- Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors
- (2015) Dae-Shik Suh et al. JOURNAL OF PROTEOME RESEARCH
- RNAi-mediated knockdown of inhibin α subunit increased apoptosis in granulosa cells and decreased fertility in mice
- (2015) Ishwari Kadariya et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development
- (2015) Zhilin Liu et al. MOLECULAR ENDOCRINOLOGY
- Therapy-resistant acute lymphoblastic leukemia (ALL) cells inactivate FOXO3 to escape apoptosis induction by TRAIL and Noxa
- (2015) Michael J Ausserlechner et al. Oncotarget
- Adult granulosa cell tumours of the ovary
- (2014) Rosanna Mancari et al. CURRENT OPINION IN ONCOLOGY
- Inhibin at 90: From Discovery to Clinical Application, a Historical Review
- (2014) Yogeshwar Makanji et al. ENDOCRINE REVIEWS
- Follicle-stimulating hormone synthesis and fertility depend on SMAD4 and FOXL2
- (2014) Jérôme Fortin et al. FASEB JOURNAL
- TGFβ Signaling Promotes Juvenile Granulosa Cell Tumorigenesis by Suppressing Apoptosis
- (2014) Nadéra Mansouri-Attia et al. MOLECULAR ENDOCRINOLOGY
- Oocyte-derived BMP15 but not GDF9 down-regulates connexin43 expression and decreases gap junction intercellular communication activity in immortalized human granulosa cells
- (2014) Hsun-Ming Chang et al. MOLECULAR HUMAN REPRODUCTION
- FOXL2, GATA4, and SMAD3 Co-Operatively Modulate Gene Expression, Cell Viability and Apoptosis in Ovarian Granulosa Cell Tumor Cells
- (2014) Mikko Anttonen et al. PLoS One
- Anti-VEGFA Therapy Reduces Tumor Growth and Extends Survival in a Murine Model of Ovarian Granulosa Cell Tumor
- (2014) Mayra Tsoi et al. Translational Oncology
- HER2 and GATA4 are new prognostic factors for early-stage ovarian granulosa cell tumor-a long-term follow-up study
- (2014) Anniina Färkkilä et al. Cancer Medicine
- FOXL2-induced follistatin attenuates activin A-stimulated cell proliferation in human granulosa cell tumors
- (2013) Jung-Chien Cheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Effects of an Inhibitor of the Gamma-Secretase Complex on Proliferation and Apoptotic Parameters in a FOXL2-Mutated Granulosa Tumor Cell Line (KGN)1
- (2013) Griselda Irusta et al. BIOLOGY OF REPRODUCTION
- Genetic changes in nonepithelial ovarian cancer
- (2013) Els Van Nieuwenhuysen et al. Expert Review of Anticancer Therapy
- The role of FOXL2 in the pathogenesis of adult ovarian granulosa cell tumours
- (2013) Roseanne Rosario et al. GYNECOLOGIC ONCOLOGY
- Granulosa cell tumor mutant FOXL2C134W suppresses GDF-9 and activin A-induced follistatin transcription in primary granulosa cells
- (2013) Kirsten J. McTavish et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Betaglycan Alters NFκB-TGFβ2 Cross Talk to Reduce Survival of Human Granulosa Tumor Cells
- (2013) Maree Bilandzic et al. MOLECULAR ENDOCRINOLOGY
- SelectiveSmad4Knockout in Ovarian Preovulatory Follicles Results in Multiple Defects in Ovulation
- (2013) Chao Yu et al. MOLECULAR ENDOCRINOLOGY
- Overexpression of Wild-Type but Not C134W Mutant FOXL2 Enhances GnRH-Induced Cell Apoptosis by Increasing GnRH Receptor Expression in Human Granulosa Cell Tumors
- (2013) Jung-Chien Cheng et al. PLoS One
- TGFβ signalling in context
- (2012) Joan Massagué NATURE REVIEWS MOLECULAR CELL BIOLOGY
- BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors
- (2012) S K Tripurani et al. ONCOGENE
- GATA-4 and FOG-2 Expression in Pediatric Ovarian Sex Cord-Stromal Tumors Replicates Embryonal Gonadal Phenotype: Results from the TREP Project
- (2012) Calogero Virgone et al. PLoS One
- The Transcriptional Targets of Mutant FOXL2 in Granulosa Cell Tumours
- (2012) Roseanne Rosario et al. PLoS One
- Immunohistochemical Characterization of Nonhuman Primate Ovarian Sex Cord–Stromal Tumors
- (2012) A. Durkes et al. VETERINARY PATHOLOGY
- Akt, FoxO and regulation of apoptosis
- (2011) Xinbo Zhang et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- New targets for old hormones: inhibins clinical role revisited [Review]
- (2011) Padmanaban S. Suresh et al. ENDOCRINE JOURNAL
- Serum Vascular Endothelial Growth Factor A (VEGF) Is Elevated in Patients with Ovarian Granulosa Cell Tumor (GCT), and VEGF Inhibition by Bevacizumab Induces Apoptosis in GCTin Vitro
- (2011) Anniina Färkkilä et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Anti-Müllerian hormone inhibits growth of AMH type II receptor-positive human ovarian granulosa cell tumor cells by activating apoptosis
- (2011) Mikko Anttonen et al. LABORATORY INVESTIGATION
- Bone morphogenetic protein signaling transcription factor (SMAD) function in granulosa cells
- (2011) Stephanie A. Pangas MOLECULAR AND CELLULAR ENDOCRINOLOGY
- GATA4 protects granulosa cell tumors from TRAIL-induced apoptosis
- (2010) Antti Kyrönlahti et al. ENDOCRINE-RELATED CANCER
- Vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 are highly expressed in ovarian granulosa cell tumors
- (2010) Anniina Färkkilä et al. EUROPEAN JOURNAL OF ENDOCRINOLOGY
- The Role of Inhibins B and Antimüllerian Hormone for Diagnosis and Follow-up of Granulosa Cell Tumors
- (2010) Inge Geerts et al. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER
- Inhibin-A Antagonizes TGFβ2 Signaling by Down-Regulating Cell Surface Expression of the TGFβ Coreceptor Betaglycan
- (2010) Brendan D. Looyenga et al. MOLECULAR ENDOCRINOLOGY
- Granulosa Cell-Expressed BMPR1A and BMPR1B Have Unique Functions in Regulating Fertility but Act Redundantly to Suppress Ovarian Tumor Development
- (2010) Mark A. Edson et al. MOLECULAR ENDOCRINOLOGY
- Differential apoptotic activities of wild-type FOXL2 and the adult-type granulosa cell tumor-associated mutant FOXL2 (C134W)
- (2010) J-H Kim et al. ONCOGENE
- Functional Exploration of the Adult Ovarian Granulosa Cell Tumor-Associated Somatic FOXL2 Mutation p.Cys134Trp (c.402C>G)
- (2010) Bérénice A. Benayoun et al. PLoS One
- Bone morphogenetic proteins (BMPs): From morphogens to metabologens
- (2009) A. Hari Reddi et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Loss of inhibin alpha uncouples oocyte-granulosa cell dynamics and disrupts postnatal folliculogenesis
- (2009) Michelle Myers et al. DEVELOPMENTAL BIOLOGY
- Serum Müllerian Inhibiting Substance/Anti-Müllerian Hormone levels in patients with adult granulosa cell tumors directly correlate with aggregate tumor mass as determined by pathology or radiology
- (2009) Henry L. Chang et al. GYNECOLOGIC ONCOLOGY
- Anti-angiogenesis therapy with bevacizumab for patients with ovarian granulosa cell tumors
- (2009) Xia Tao et al. GYNECOLOGIC ONCOLOGY
- Tumeurs juvéniles de la granulosa : expression clinique et moléculaire
- (2009) N. Kalfa et al. GYNECOLOGIE OBSTETRIQUE & FERTILITE
- Loss of Betaglycan Contributes to the Malignant Properties of Human Granulosa Tumor Cells
- (2009) Maree Bilandzic et al. MOLECULAR ENDOCRINOLOGY
- Mutation ofFOXL2in Granulosa-Cell Tumors of the Ovary
- (2009) Sohrab P. Shah et al. NEW ENGLAND JOURNAL OF MEDICINE
- Synergistic effects of Pten loss and WNT/CTNNB1 signaling pathway activation in ovarian granulosa cell tumor development and progression
- (2008) Marie-Noëlle Laguë et al. CARCINOGENESIS
- GATA-4 Regulates Bcl-2 Expression in Ovarian Granulosa Cell Tumors
- (2008) Antti Kyrönlahti et al. ENDOCRINOLOGY
- Glucose metabolism and angiogenesis in granulosa cell tumors of the ovary: Activation of Akt, expression of M2PK, TKTL1 and VEGF
- (2008) Melanie Schmidt et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Activin signals via SMAD2/3 between germ and somatic cells in the human fetal ovary and regulates kit ligand expression
- (2007) Shiona M. Coutts et al. DEVELOPMENTAL BIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now