Acute administration of the NMDA receptor antagonists ketamine and MK-801 reveals dysregulation of glutamatergic signalling and sensorimotor gating in the Sapap3 knockout mouse model of compulsive-like behaviour

Effect of psilocybin on marble burying in ICR mice: role of 5-HT1A receptors and implications for the treatment of obsessive-compulsive disorder

(2023) Sandeep Singh et al.   Translational Psychiatry

SAPAP3 regulates epileptic seizures involving GluN2A in post-synaptic densities

(2022) Yanke Zhang et al.   Cell Death & Disease

Ketamine in the Treatment of Obsessive-Compulsive Disorder: A Systematic Review

(2022) Igor D. Bandeira et al.   HARVARD REVIEW OF PSYCHIATRY

Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice

(2021) Elizabeth E. Manning et al.   Scientific Reports

Optogenetic inhibition of indirect pathway neurons in the dorsomedial striatum reduces excessive grooming in Sapap3-knockout mice

(2021) Kathia I. Ramírez-Armenta et al.   NEUROPSYCHOPHARMACOLOGY

Therapeutic Potentials of Ketamine and Esketamine in Obsessive–Compulsive Disorder (OCD), Substance Use Disorders (SUD) and Eating Disorders (ED): A Review of the Current Literature

(2021) Giovanni Martinotti et al.   Brain Sciences

Ketamine increases activity of a fronto-striatal projection that regulates compulsive behavior in SAPAP3 knockout mice

(2021) Gwynne L. Davis et al.   Nature Communications

Glutamatergic medications as adjunctive therapy for moderate to severe obsessive-compulsive disorder in adults: a systematic review and meta-analysis

(2021) Fatemeh Hadi et al.   BMC Pharmacology & Toxicology

Quantification of Metabotropic Glutamate Receptor 5 Availability With Both [11C]ABP688 and [18F]FPEB Positron Emission Tomography in the Sapap3 Knockout Mouse Model for Obsessive-Compulsive–like Behavior

(2021) Dorien Glorie et al.   Biological Psychiatry-Cognitive Neuroscience and Neuroimaging

Recapitulation of Neuropsychiatric Behavioral Features in Mice Using Acute Low-dose MK-801 Administration

(2020) Darine Froy N. Mabunga et al.   Experimental Neurobiology

Antidepressant-like effects of ketamine in a mouse model of serotonergic dysfunction

(2020) Carey Wilson et al.   NEUROPHARMACOLOGY

Progression of obsessive compulsive disorder-like grooming in Sapap3 knockout mice: A longitudinal [11C]ABP688 PET study

(2020) Dorien Glorie et al.   NEUROPHARMACOLOGY

Clozapine generates obsessive compulsive disorder-like behavior in mice

(2020) Shinwon Kang et al.   Molecular Brain

Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice

(2020) Lotfi C. Hadjas et al.   NEUROPSYCHOPHARMACOLOGY

Investigating the role of 5-HT2A and 5-HT2C receptor activation in the effects of psilocybin, DOI, and citalopram on marble burying in mice

(2020) Anna U. Odland et al.   BEHAVIOURAL BRAIN RESEARCH

Lateral orbitofrontal dysfunction in the Sapap3 knockout mouse model of obsessive–compulsive disorder

(2019) Huimeng Lei et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Obsessive-Compulsive Disorder: Puzzles and Prospects

(2019) Trevor W. Robbins et al.   NEURON

Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder

(2019) Sean C. Piantadosi et al.   MOLECULAR PSYCHIATRY

Treatment of Obsessive-Compulsive Disorders (OCD) and Obsessive-Compulsive-Related Disorders (OCRD)

(2019) Waldemar Krzyszkowiak et al.   Psychiatria Polska

Higher prevalence of irritable bowel syndrome and greater gastrointestinal symptoms in obsessive-compulsive disorder

(2019) Jasmine Turna et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder

(2019) Lotfi C. Hadjas et al.   Scientific Reports

Monoamine abnormalities in the SAPAP3 knockout model of obsessive-compulsive disorder-related behaviour

(2018) Jesse Wood et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mechanism of NMDA receptor channel block by MK-801 and memantine

(2018) Xianqiang Song et al.   NATURE

Impaired instrumental reversal learning is associated with increased medial prefrontal cortex activity in Sapap3 knockout mouse model of compulsive behavior

(2018) Elizabeth E. Manning et al.   NEUROPSYCHOPHARMACOLOGY

Obsessive-Compulsive Disorder

(2017) Matthew E. Hirschtritt et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ketamine-induced behavioural and brain oxidative changes in mice: an assessment of possible beneficial effects of zinc as mono- or adjunct therapy

(2017) Olakunle James Onaolapo et al.   PSYCHOPHARMACOLOGY

Prevalence of sexual dimorphism in mammalian phenotypic traits

(2017) Natasha A. Karp et al.   Nature Communications

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

(2016) Kristen K. Ade et al.   BIOLOGICAL PSYCHIATRY

PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER

(2016) Shari A. Steinman et al.   DEPRESSION AND ANXIETY

KETAMINE'S MECHANISM OF ACTION: A PATH TO RAPID-ACTING ANTIDEPRESSANTS

(2016) Chadi G. Abdallah et al.   DEPRESSION AND ANXIETY

Men and mice: Relating their ages

(2016) Sulagna Dutta et al.   LIFE SCIENCES

BORIS: a free, versatile open-source event-logging software for video/audio coding and live observations

(2016) Olivier Friard et al.   Methods in Ecology and Evolution

Neurobiology of rodent self-grooming and its value for translational neuroscience

(2015) Allan V. Kalueff et al.   NATURE REVIEWS NEUROSCIENCE

Environmental Enrichment Ameliorates Behavioral Impairments Modeling Schizophrenia in Mice Lacking Metabotropic Glutamate Receptor 5

(2015) Emma L Burrows et al.   NEUROPSYCHOPHARMACOLOGY

Astroglial Glutamate Transporter Deficiency Increases Synaptic Excitability and Leads to Pathological Repetitive Behaviors in Mice

(2015) Tomomi Aida et al.   NEUROPSYCHOPHARMACOLOGY

Effects of single and combined gabapentin use in elevated plus maze and forced swimming tests

(2014) Fatma Sultan Kilic et al.   ACTA NEUROPSYCHIATRICA

Obsessive-compulsive disorder

(2014) D. Veale et al.   BMJ-British Medical Journal

Ketamine increases striatal dopamine release and hyperlocomotion in adult rats after postnatal functional blockade of the prefrontal cortex

(2013) Y. Usun et al.   BEHAVIOURAL BRAIN RESEARCH

Circuit-Selective Striatal Synaptic Dysfunction in the Sapap3 Knockout Mouse Model of Obsessive-Compulsive Disorder

(2013) Yehong Wan et al.   BIOLOGICAL PSYCHIATRY

Prepulse inhibition in psychiatric disorders – Apart from schizophrenia

(2013) S. Kohl et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept

(2013) Carolyn I Rodriguez et al.   NEUROPSYCHOPHARMACOLOGY

Update: Studies of prepulse inhibition of startle, with particular relevance to the pathophysiology or treatment of Tourette Syndrome

(2012) Neal R. Swerdlow   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Pharmacological Management of Treatment-Resistant Obsessive-Compulsive Disorder

(2011) Anat Abudy et al.   CNS DRUGS

Neurobiology of obsessive–compulsive disorder: insights into neural circuitry dysfunction through mouse genetics

(2011) Jonathan T Ting et al.   CURRENT OPINION IN NEUROBIOLOGY

Molecular basis of NMDA receptor functional diversity

(2011) Pierre Paoletti   EUROPEAN JOURNAL OF NEUROSCIENCE

Sapap3 Deletion Anomalously Activates Short-Term Endocannabinoid-Mediated Synaptic Plasticity

(2011) M. Chen et al.   JOURNAL OF NEUROSCIENCE

Sapap3 Deletion Causes mGluR5-Dependent Silencing of AMPAR Synapses

(2011) Y. Wan et al.   JOURNAL OF NEUROSCIENCE

A Single-Blinded Case-Control Study of Memantine in Severe Obsessive-Compulsive Disorder

(2010) S. Evelyn Stewart et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Effects ofPsilocybe argentipeson Marble-Burying Behavior in Mice

(2009) Yoshihiro MATSUSHIMA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Obsessive-compulsive disorder

(2009) Jonathan S Abramowitz et al.   LANCET

Meta-analysis of the dose-response relationship of SSRI in obsessive-compulsive disorder

(2009) M H Bloch et al.   MOLECULAR PSYCHIATRY

Riluzole Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder

(2008) Christopher Pittenger et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Involvement of Pallidotegmental Neurons in Methamphetamine- and MK-801-Induced Impairment of Prepulse Inhibition of the Acoustic Startle Reflex in Mice: Reversal by GABAB Receptor Agonist Baclofen

(2008) Sawako Arai et al.   NEUROPSYCHOPHARMACOLOGY