Therapeutic Potentials of Ketamine and Esketamine in Obsessive–Compulsive Disorder (OCD), Substance Use Disorders (SUD) and Eating Disorders (ED): A Review of the Current Literature

Ketamine—50 years in use: from anesthesia to rapid antidepressant effects and neurobiological mechanisms

(2021) Samuel Kohtala   Pharmacological Reports

Ketamine induces immediate and delayed alterations of OCD-like behavior

(2020) Summer L. Thompson et al.   PSYCHOPHARMACOLOGY

Overlap in the neural circuitry and molecular mechanisms underlying ketamine abuse and its use as an antidepressant

(2020) Saurabh S. Kokane et al.   BEHAVIOURAL BRAIN RESEARCH

Are NMDA and opioid receptors involved in the antidepressant actions of ketamine?

(2020) Kenji Hashimoto   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical Utility of Repeated Intravenous Ketamine Treatment for Resistant Obsessive-Compulsive Disorder

(2020) Lavanya P Sharma et al.   Asian Journal of Psychiatry

Registered clinical trials investigating ketamine for psychiatric disorders

(2020) Bahareh Peyrovian et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Anorexia nervosa, zinc deficiency and the glutamate system: The ketamine option

(2020) Daniel F. Hermens et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Remission from Chronic Anorexia Nervosa With Ketogenic Diet and Ketamine: Case Report

(2020) Barbara Scolnick et al.   Frontiers in Psychiatry

Safety of Repeated Administration of Parenteral Ketamine for Depression

(2020) David Feifel et al.   Pharmaceuticals

Psychedelic Treatments for Psychiatric Disorders: A Systematic Review and Thematic Synthesis of Patient Experiences in Qualitative Studies

(2020) Joost J. Breeksema et al.   CNS DRUGS

Mystical-type experiences occasioned by ketamine mediate its impact on at-risk drinking: Results from a randomized, controlled trial

(2020) Rebecca L Rothberg et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Glutamate Systems in DSM-5 Anxiety Disorders: Their Role and a Review of Glutamate and GABA Psychopharmacology

(2020) Madeeha Nasir et al.   Frontiers in Psychiatry

Generality and opponency of rostromedial tegmental (RMTg) roles in valence processing

(2019) Hao Li et al.   eLife

Association of Combined Naltrexone and Ketamine With Depressive Symptoms in a Case series of Patients With Depression and Alcohol Use Disorder

(2019) Gihyun Yoon et al.   JAMA Psychiatry

A Single Ketamine Infusion Combined With Mindfulness-Based Behavioral Modification to Treat Cocaine Dependence: A Randomized Clinical Trial

(2019) Elias Dakwar et al.   AMERICAN JOURNAL OF PSYCHIATRY

Esketamine for treatment resistant depression

(2019) Jennifer Swainson et al.   Expert Review of Neurotherapeutics

Attenuation of antidepressant and antisuicidal effects of ketamine by opioid receptor antagonism

(2019) Nolan R. Williams et al.   MOLECULAR PSYCHIATRY

Ketamine and Cognitive Behavioral Therapy for Rapid Opioid Tapering with Sustained Opioid Abstinence: a Case Report and 1‐Year Follow Up

(2019) Aaron C. Ocker et al.   Pain Practice

Ketamine for suicidal ideation in adults with psychiatric disorders: A systematic review and meta-analysis of treatment trials

(2019) Katrina Witt et al.   AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY

Ketamine can reduce harmful drinking by pharmacologically rewriting drinking memories

(2019) Ravi K. Das et al.   Nature Communications

Molecular and cellular mechanisms underlying the antidepressant effects of ketamine enantiomers and its metabolites

(2019) Chun Yang et al.   Translational Psychiatry

A Single Ketamine Infusion Combined With Motivational Enhancement Therapy for Alcohol Use Disorder: A Randomized Midazolam-Controlled Pilot Trial

(2019) Elias Dakwar et al.   AMERICAN JOURNAL OF PSYCHIATRY

Three Rostromedial Tegmental Afferents Drive Triply Dissociable Aspects of Punishment Learning and Aversive Valence Encoding

(2019) Hao Li et al.   NEURON

The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

(2018) Samuel T. Wilkinson et al.   AMERICAN JOURNAL OF PSYCHIATRY

Pharmacotherapy for Alcohol Use Disorder

(2018) Stephen R. Holt et al.   MEDICAL CLINICS OF NORTH AMERICA

Mechanisms of ketamine action as an antidepressant

(2018) P Zanos et al.   MOLECULAR PSYCHIATRY

A sub-set of psychoactive effects may be critical to the behavioral impact of ketamine on cocaine use disorder: Results from a randomized, controlled laboratory study

(2018) E. Dakwar et al.   NEUROPHARMACOLOGY

Ketamine for the treatment of addiction: Evidence and potential mechanisms

(2018) I. Ivan Ezquerra-Romano et al.   NEUROPHARMACOLOGY

New steps for treating alcohol use disorder

(2018) Erin J. Campbell et al.   PSYCHOPHARMACOLOGY

Psychopharmacological treatment of Obsessive-Compulsive Disorder (OCD)

(2018) Antonio Del Casale et al.   Current Neuropharmacology

Single injection of ketamine during mid-adolescence promotes long-lasting resilience to activity-based anorexia of female mice by increasing food intake and attenuating hyperactivity as well as anxiety-like behavior

(2018) Yi-Wen Chen et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

Crosstalk Between Inflammation and Glutamate System in Depression: Signaling Pathway and Molecular Biomarkers for Ketamine’s Antidepressant Effect

(2018) Wenyan Cui et al.   MOLECULAR NEUROBIOLOGY

Efficacy of Ketamine in the Treatment of Substance Use Disorders: A Systematic Review

(2018) Jennifer L. Jones et al.   Frontiers in Psychiatry

What is the mechanism of Ketamine's rapid-onset antidepressant effect? A concise overview of the surprisingly large number of possibilities

(2017) S. E. Strasburger et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Challenges in Testing Intranasal Ketamine in Obsessive-Compulsive Disorder

(2017) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

Intranasal Ketamine and Cognitive-Behavioral Therapy for Treatment-Refractory Obsessive-Compulsive Disorder

(2017) Thomas G. Adams et al.   JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY

Ketamine as a rapid-acting agent for suicidal ideation: A meta-analysis

(2017) Francesco Bartoli et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A proof-of-concept investigation into ketamine as a pharmacological treatment for alcohol dependence: study protocol for a randomised controlled trial

(2017) Amy McAndrew et al.   Trials

Psychopharmacological advances in eating disorders

(2017) Hubertus Himmerich et al.   Expert Review of Clinical Pharmacology

Clarifying the prospective relationships between social anxiety and eating disorder symptoms and underlying vulnerabilities

(2016) Cheri A. Levinson et al.   APPETITE

Experience of the use of Ketamine to manage opioid withdrawal in an addicted woman: a case report

(2016) Laurence Lalanne et al.   BMC Psychiatry

Open-Label Trial on the Effects of Memantine in Adults With Obsessive-Compulsive Disorder After a Single Ketamine Infusion

(2016) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

Can Exposure-Based CBT Extend the Effects of Intravenous Ketamine in Obsessive-Compulsive Disorder?

(2016) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

Cocaine self-administration disrupted by the N-methyl-D-aspartate receptor antagonist ketamine: a randomized, crossover trial

(2016) E Dakwar et al.   MOLECULAR PSYCHIATRY

Altered structural and effective connectivity in anorexia and bulimia nervosa in circuits that regulate energy and reward homeostasis

(2016) G K W Frank et al.   Translational Psychiatry

Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula

(2015) Frank J Meye et al.   NATURE NEUROSCIENCE

In vivo effects of ketamine on glutamate-glutamine and gamma-aminobutyric acid in obsessive-compulsive disorder: Proof of concept

(2015) Carolyn I. Rodriguez et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Evaluation of Adjunctive Ketamine to Benzodiazepines for Management of Alcohol Withdrawal Syndrome

(2014) Adrian Wong et al.   ANNALS OF PHARMACOTHERAPY

Therapeutic infusions of ketamine: Do the psychoactive effects matter?

(2014) E. Dakwar et al.   DRUG AND ALCOHOL DEPENDENCE

The Effects of Subanesthetic Ketamine Infusions on Motivation to Quit and Cue-Induced Craving in Cocaine-Dependent Research Volunteers

(2013) Elias Dakwar et al.   BIOLOGICAL PSYCHIATRY

Two cases of delayed-onset suicidal ideation, dysphoria and anxiety after ketamine infusion in patients with obsessive–compulsive disorder and a history of major depressive disorder

(2013) Mark J Niciu et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Rapid, transient synaptic plasticity in addiction

(2013) Cassandra D. Gipson et al.   NEUROPHARMACOLOGY

Randomized Controlled Crossover Trial of Ketamine in Obsessive-Compulsive Disorder: Proof-of-Concept

(2013) Carolyn I Rodriguez et al.   NEUROPSYCHOPHARMACOLOGY

The association of interoceptive awareness and alexithymia with neurotransmitter concentrations in insula and anterior cingulate

(2013) Jutta Ernst et al.   Social Cognitive and Affective Neuroscience

Effects of Ketamine in Treatment-Refractory Obsessive-Compulsive Disorder

(2012) Michael H. Bloch et al.   BIOLOGICAL PSYCHIATRY

Ketamine for Depression: Where Do We Go from Here?

(2012) Marije aan het Rot et al.   BIOLOGICAL PSYCHIATRY

The Action of Antidepressants on the Glutamate System: Regulation of Glutamate Release and Glutamate Receptors

(2012) Laura Musazzi et al.   BIOLOGICAL PSYCHIATRY

Neurobiology of obsessive–compulsive disorder: insights into neural circuitry dysfunction through mouse genetics

(2011) Jonathan T Ting et al.   CURRENT OPINION IN NEUROBIOLOGY

Rapid Resolution of Obsessions After an Infusion of Intravenous Ketamine in a Patient With Treatment-Resistant Obsessive-Compulsive Disorder

(2011) Carolyn I. Rodriguez et al.   JOURNAL OF CLINICAL PSYCHIATRY

The stressed synapse: the impact of stress and glucocorticoids on glutamate transmission

(2011) Maurizio Popoli et al.   NATURE REVIEWS NEUROSCIENCE

Anorexia nervosa versus hyperinsulinism: therapeutic effects of neuropharmacological manipulation

(2011) Fuad Lechin et al.   Therapeutics and Clinical Risk Management

Chronic ketamine use increases serum levels of brain-derived neurotrophic factor

(2010) Valerio Ricci et al.   PSYCHOPHARMACOLOGY

Serum glutamine, set-shifting ability and anorexia nervosa

(2010) Michiko Nakazato et al.   Annals of General Psychiatry

Pregabalin versus naltrexone in alcohol dependence: a randomised, double-blind, comparison trial

(2009) G. Martinotti et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Anti-Brain Autoantibodies and Altered Excitatory Neurotransmitters in Obsessive–Compulsive Disorder

(2009) Sagnik Bhattacharyya et al.   NEUROPSYCHOPHARMACOLOGY

The glutamate-based genetic immune hypothesis in obsessive-compulsive disorder. An integrative approach from genes to symptoms

(2009) J.Y. Rotge et al.   NEUROSCIENCE

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE