Disruption of prepulse inhibition is associated with compulsive behavior severity and nucleus accumbens dopamine receptor changes in Sapap3 knockout mice

A cross-species assessment of behavioral flexibility in compulsive disorders

(2021) Nabil Benzina et al.   Communications Biology

Instrumental learning in a mouse model for obsessive-compulsive disorder: Impaired habit formation in Sapap3 mutants

(2020) I. Ehmer et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Projection-specific deficits in synaptic transmission in adult Sapap3-knockout mice

(2020) Lotfi C. Hadjas et al.   NEUROPSYCHOPHARMACOLOGY

Strengthened inputs from secondary motor cortex to striatum in a mouse model of compulsive behavior

(2019) Victoria L. Corbit et al.   JOURNAL OF NEUROSCIENCE

Behavioral flexibility in a mouse model for obsessive-compulsive disorder: Impaired Pavlovian reversal learning in SAPAP3 mutants

(2019) Bastijn J.G. van den Boom et al.   GENES BRAIN AND BEHAVIOR

Lower excitatory synaptic gene expression in orbitofrontal cortex and striatum in an initial study of subjects with obsessive compulsive disorder

(2019) Sean C. Piantadosi et al.   MOLECULAR PSYCHIATRY

Aberrant habit formation in the Sapap3-knockout mouse model of obsessive-compulsive disorder

(2019) Lotfi C. Hadjas et al.   Scientific Reports

Differential Effects of Deep Brain Stimulation of the Internal Capsule and the Striatum on Excessive Grooming in Sapap3 Mutant Mice

(2018) Cindy M. Pinhal et al.   BIOLOGICAL PSYCHIATRY

Monoamine abnormalities in the SAPAP3 knockout model of obsessive-compulsive disorder-related behaviour

(2018) Jesse Wood et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Impaired instrumental reversal learning is associated with increased medial prefrontal cortex activity in Sapap3 knockout mouse model of compulsive behavior

(2018) Elizabeth E. Manning et al.   NEUROPSYCHOPHARMACOLOGY

Dorsal striatum D1-expressing neurons are involved with sensorimotor gating on prepulse inhibition test

(2017) Samanta Rodrigues et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Revealing the complex genetic architecture of obsessive–compulsive disorder using meta-analysis

(2017) Paul D Arnold et al.   MOLECULAR PSYCHIATRY

Increased Metabotropic Glutamate Receptor 5 Signaling Underlies Obsessive-Compulsive Disorder-like Behavioral and Striatal Circuit Abnormalities in Mice

(2016) Kristen K. Ade et al.   BIOLOGICAL PSYCHIATRY

PREPULSE INHIBITION DEFICITS ONLY IN FEMALES WITH OBSESSIVE-COMPULSIVE DISORDER

(2016) Shari A. Steinman et al.   DEPRESSION AND ANXIETY

Prepulse Inhibition Deficits in Obsessive-Compulsive Disorder are More Pronounced in Females

(2016) Susanne E Ahmari et al.   NEUROPSYCHOPHARMACOLOGY

Age-related changes in behavior in C57BL/6J mice from young adulthood to middle age

(2016) Hirotaka Shoji et al.   Molecular Brain

Histidine Decarboxylase Deficiency Causes Tourette Syndrome: Parallel Findings in Humans and Mice

(2014) Lissandra Castellan Baldan et al.   NEURON

Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex

(2013) Bianca Jupp et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Dopaminergic activity in Tourette syndrome and obsessive-compulsive disorder

(2013) Damiaan Denys et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Double deletion of melanocortin 4 receptors and SAPAP3 corrects compulsive behavior and obesity in mice

(2013) P. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Optogenetic Stimulation of Lateral Orbitofronto-Striatal Pathway Suppresses Compulsive Behaviors

(2013) E. Burguiere et al.   SCIENCE

Repeated Cortico-Striatal Stimulation Generates Persistent OCD-Like Behavior

(2013) S. E. Ahmari et al.   SCIENCE

BDNF deficiency and young-adult methamphetamine induce sex-specific effects on prepulse inhibition regulation

(2013) Elizabeth E. Manning et al.   Frontiers in Cellular Neuroscience

Impaired Sensorimotor Gating in Unmedicated Adults with Obsessive–Compulsive Disorder

(2012) Susanne E Ahmari et al.   NEUROPSYCHOPHARMACOLOGY

Essential Role for Orbitofrontal Serotonin 1B Receptors in Obsessive-Compulsive Disorder-Like Behavior and Serotonin Reuptake Inhibitor Response in Mice

(2011) Nancy A. Shanahan et al.   BIOLOGICAL PSYCHIATRY

Cue-induced striatal dopamine release in Parkinson's disease-associated impulsive-compulsive behaviours

(2011) S. S. O'Sullivan et al.   BRAIN

Lesions of the dorsomedial striatum disrupt prepulse inhibition

(2011) L.C. Baldan Ramsey et al.   NEUROSCIENCE

Enhanced Striatal Dopamine Release During Food Stimulation in Binge Eating Disorder

(2011) Gene-Jack Wang et al.   Obesity

Age-associated improvements in cross-modal prepulse inhibition in mice.

(2010) Jared W. Young et al.   BEHAVIORAL NEUROSCIENCE

Psychotropic drug-induced locomotor hyperactivity and prepulse inhibition regulation in male and female aromatase knockout (ArKO) mice: role of dopamine D1 and D2 receptors and dopamine transporters

(2009) Carolina Chavez et al.   PSYCHOPHARMACOLOGY

Chronic Reductions in Serotonin Transporter Function Prevent 5-HT1B-Induced Behavioral Effects in Mice

(2008) Nancy A. Shanahan et al.   BIOLOGICAL PSYCHIATRY

Dopamine D1 receptor binding in the striatum of patients with obsessive–compulsive disorder

(2008) James S. Olver et al.   JOURNAL OF AFFECTIVE DISORDERS

Multiple rare SAPAP3 missense variants in trichotillomania and OCD

(2008) S Züchner et al.   MOLECULAR PSYCHIATRY

In vivo PET study of 5HT2A serotonin and D2 dopamine dysfunction in drug-naive obsessive-compulsive disorder

(2008) Daniela Perani et al.   NEUROIMAGE