Green tea extract provides extensive Nrf2-independent protection against lipid accumulation and NFκB pro- inflammatory responses during nonalcoholic steatohepatitis in mice fed a high-fat diet

The effect of bioactive compounds in tea on lipid metabolism and obesity through regulation of peroxisome proliferator-activated receptors

(2015) Sung-Joon Lee et al.   CURRENT OPINION IN LIPIDOLOGY

The gut microbiota and host health: a new clinical frontier

(2015) Julian R Marchesi et al.   GUT

Epigallocatechin Gallate (EGCG) Suppresses Lipopolysaccharide-Induced Toll-like Receptor 4 (TLR4) Activity via 67 kDa Laminin Receptor (67LR) in 3T3-L1 Adipocytes

(2015) Suqing Bao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Green Tea Lowers Hepatic COX-2 and Prostaglandin E2 in Rats with Dietary Fat-Induced Nonalcoholic Steatohepatitis

(2015) Min-Yu Chung et al.   JOURNAL OF MEDICINAL FOOD

The Dual Role of Nrf2 in Nonalcoholic Fatty Liver Disease: Regulation of Antioxidant Defenses and Hepatic Lipid Metabolism

(2015) Sílvia S. Chambel et al.   Biomed Research International

Epigallocatechin-3-gallate (EGCG) attenuates concanavalin A-induced hepatic injury in mice

(2014) Dongmei Liu et al.   ACTA HISTOCHEMICA

Treatment with baicalein attenuates methionine−choline deficient diet-induced non-alcoholic steatohepatitis in rats

(2014) Hai-Guang Xin et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Susceptibility of Nrf2-Null Mice to Steatohepatitis and Cirrhosis upon Consumption of a High-Fat Diet Is Associated with Oxidative Stress, Perturbation of the Unfolded Protein Response, and Disturbance in the Expression of Metabolic Enzymes but Not with Insulin Resistance

(2014) P. J. Meakin et al.   MOLECULAR AND CELLULAR BIOLOGY

Transcription Factor Nrf1 Negatively Regulates the Cystine/Glutamate Transporter and Lipid-Metabolizing Enzymes

(2014) T. Tsujita et al.   MOLECULAR AND CELLULAR BIOLOGY

γ-Tocopherol-rich supplementation additively improves vascular endothelial function during smoking cessation

(2013) Eunice Mah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 Orchestrates Fuel Partitioning for Cell Proliferation

(2012) John D. Hayes et al.   Cell Metabolism

Nrf2: A Potential Target for New Therapeutics in Liver Disease

(2012) A M Bataille et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

(2012) Geoffrey C. Farrell et al.   Gut and Liver

Tumor necrosis factor receptor 1 gain-of-function mutation aggravates nonalcoholic fatty liver disease but does not cause insulin resistance in a murine model*

(2012) Marcela Aparicio-Vergara et al.   HEPATOLOGY

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

(2012) Emilie E. Vomhof-DeKrey et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

NF-E2-Related Factor 1 (Nrf1) Serves as a Novel Regulator of Hepatic Lipid Metabolism through Regulation of the Lipin1 and PGC-1  Genes

(2012) Y. Hirotsu et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of starch digestion by the green tea polyphenol, (−)-epigallocatechin-3-gallate

(2012) Sarah C. Forester et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Therapeutic potential of green tea in nonalcoholic fatty liver disease

(2012) Christopher Masterjohn et al.   NUTRITION REVIEWS

Conditional Deletion ofNrf2in Airway Epithelium Exacerbates Acute Lung Injury and Impairs the Resolution of Inflammation

(2011) Narsa M. Reddy et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Effects of Green Tea Polyphenol (−)-Epigallocatechin-3-gallate on Newly Developed High-Fat/Western-Style Diet-Induced Obesity and Metabolic Syndrome in Mice

(2011) Yu-Kuo Chen et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Green Tea Extract Suppresses NFκB Activation and Inflammatory Responses in Diet-Induced Obese Rats with Nonalcoholic Steatohepatitis

(2011) Hea Jin Park et al.   JOURNAL OF NUTRITION

Beneficial Role of Nrf2 in Regulating NADPH Generation and Consumption

(2011) Kai Connie Wu et al.   TOXICOLOGICAL SCIENCES

(−)-Epigallocatechin-3-gallate increases the expression of genes related to fat oxidation in the skeletal muscle of high fat-fed mice

(2011) Sudathip Sae-tan et al.   Food & Function

Small Intestinal Bacterial Overgrowth in Nonalcoholic Steatohepatitis: Association with Toll-Like Receptor 4 Expression and Plasma Levels of Interleukin 8

(2010) Ahmed Abu Shanab et al.   DIGESTIVE DISEASES AND SCIENCES

Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

(2010) V. W.-S. Wong et al.   GUT

Nonalcoholic fatty liver disease (NAFLD) activity score and the histopathologic diagnosis in NAFLD: distinct clinicopathologic meanings

(2010) Elizabeth M. Brunt et al.   HEPATOLOGY

Green tea extract attenuates hepatic steatosis by decreasing adipose lipogenesis and enhancing hepatic antioxidant defenses in ob/ob mice

(2010) Hea Jin Park et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Role of tumor necrosis factor α (TNFα) in the onset of fructose-induced nonalcoholic fatty liver disease in mice

(2010) Giridhar Kanuri et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver

(2010) Neil R. Kitteringham et al.   Journal of Proteomics

Tea catechin auto-oxidation dimers are accumulated and retained by Caco-2 human intestinal cells

(2010) Andrew P. Neilson et al.   NUTRITION RESEARCH

Enhanced expression of Nrf2 in mice attenuates the fatty liver produced by a methionine- and choline-deficient diet☆

(2010) Yu-Kun Jennifer Zhang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Deletion of nuclear factor-E2-related factor-2 leads to rapid onset and progression of nutritional steatohepatitis in mice

(2009) Hirokazu Sugimoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Genetic versus chemoprotective activation of Nrf2 signaling: overlapping yet distinct gene expression profiles between Keap1 knockout and triterpenoid-treated mice

(2009) Melinda S. Yates et al.   CARCINOGENESIS

Loss of Nrf2 markedly exacerbates nonalcoholic steatohepatitis

(2009) Sudhir Chowdhry et al.   FREE RADICAL BIOLOGY AND MEDICINE

VSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice

(2009) Arumugam Velayudham et al.   HEPATOLOGY

Liver NF-κB and AP-1 DNA Binding in Obese Patients

(2009) Luis A. Videla et al.   Obesity

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

Safety of Green Tea Extracts

(2008) Dandapantula N Sarma et al.   DRUG SAFETY

Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes

(2008) Makiko Ohtsuji et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NF-E2-Related Factor 2 Inhibits Lipid Accumulation and Oxidative Stress in Mice Fed a High-Fat Diet

(2008) Y. Tanaka et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Molecular mechanisms of Nrf2-mediated antioxidant response

(2008) Wenge Li et al.   MOLECULAR CARCINOGENESIS

Modulation of Nrf2-mediated antioxidant and detoxifying enzyme induction by the green tea polyphenol EGCG

(2007) Hye-Kyung Na et al.   FOOD AND CHEMICAL TOXICOLOGY