Advances in mass spectrometry to unravel the structure and function of protein condensates
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Advances in mass spectrometry to unravel the structure and function of protein condensates
Authors
Keywords
-
Journal
Nature Protocols
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-10-31
DOI
10.1038/s41596-023-00900-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Mass Spectrometry of RNA-Binding Proteins during Liquid–Liquid Phase Separation Reveals Distinct Assembly Mechanisms and Droplet Architectures
- (2023) Cagla Sahin et al. Journal of the American Chemical Society
- Ion Mobility Mass Spectrometry Unveils Global Protein Conformations in Response to Conditions that Promote and Reverse Liquid–Liquid Phase Separation
- (2023) Christina Glen Robb et al. Journal of the American Chemical Society
- Liquid–Liquid Phase Separation Primes Spider Silk Proteins for Fiber Formation via a Conditional Sticker Domain
- (2023) Axel Leppert et al. Nano Letters
- Direct Observation of “Elongated” Conformational States in α‐Synuclein upon Liquid‐Liquid Phase Separation
- (2022) Daniele Ubbiali et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mass Spectrometry and Machine Learning Reveal Determinants of Client Recognition by Antiamyloid Chaperones
- (2022) Nicklas Österlund et al. MOLECULAR & CELLULAR PROTEOMICS
- Investigating how intrinsically disordered regions contribute to protein function using HDX-MS
- (2022) Matthew A.H. Parson et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Molecular and environmental determinants of biomolecular condensate formation
- (2022) José A. Villegas et al. Nature Chemical Biology
- Biomolecular condensate phase diagrams with a combinatorial microdroplet platform
- (2022) William E. Arter et al. Nature Communications
- FUS and TDP-43 Phases in Health and Disease
- (2021) Bede Portz et al. TRENDS IN BIOCHEMICAL SCIENCES
- NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation
- (2021) Leonidas Emmanouilidis et al. Nature Chemical Biology
- Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions
- (2021) Georg Krainer et al. Nature Communications
- TDP-43 condensation properties specify its RNA-binding and regulatory repertoire
- (2021) Martina Hallegger et al. CELL
- A multi-step nucleation process determines the kinetics of prion-like domain phase separation
- (2021) Erik W. Martin et al. Nature Communications
- HspB8 prevents aberrant phase transitions of FUS by chaperoning its folded RNA binding domain
- (2021) Edgar E Boczek et al. eLife
- Deciphering how naturally occurring sequence features impact the phase behaviours of disordered prion-like domains
- (2021) Anne Bremer et al. Nature Chemistry
- Capillary flow experiments for thermodynamic and kinetic characterization of protein liquid-liquid phase separation
- (2021) Emil G. P. Stender et al. Nature Communications
- The (un)structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy
- (2020) Anastasia C. Murthy et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TDP-43 α-helical structure tunes liquid–liquid phase separation and function
- (2020) Alexander E. Conicella et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Valence and patterning of aromatic residues determine the phase behavior of prion-like domains
- (2020) Erik W. Martin et al. SCIENCE
- Cross-linking/mass spectrometry at the crossroads
- (2020) Lolita Piersimoni et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Amyloid-β oligomers are captured by the DNAJB6 chaperone: Direct detection of interactions that can prevent primary nucleation
- (2020) Nicklas Österlund et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Predicting the shapes of protein complexes through collision cross section measurements and database searches
- (2020) Michael Landreh et al. ANALYTICAL CHEMISTRY
- α-Synuclein aggregation nucleates through liquid–liquid phase separation
- (2020) Soumik Ray et al. Nature Chemistry
- Emerging role of Mass Spectrometry‐Based Structural Proteomics in Elucidating Intrinsic Disorder in Proteins
- (2020) Gopa Mitra PROTEOMICS
- Structural analysis of 70S ribosomes by cross-linking/mass spectrometry reveals conformational plasticity
- (2020) Christian Tüting et al. Scientific Reports
- Unraveling Molecular Interactions in Liquid–Liquid Phase Separation of Disordered Proteins by Atomistic Simulations
- (2020) Matteo Paloni et al. JOURNAL OF PHYSICAL CHEMISTRY B
- The nucleolus as a multiphase liquid condensate
- (2020) Denis L. J. Lafontaine et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Structural rearrangement of amyloid-β upon inhibitor binding suppresses formation of Alzheimer disease related oligomers
- (2020) Tobias Lieblein et al. eLife
- Visualizing and trapping transient oligomers in amyloid assembly pathways
- (2020) Emma E. Cawood et al. BIOPHYSICAL CHEMISTRY
- Widespread occurrence of the droplet state of proteins in the human proteome
- (2020) Maarten Hardenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ion Mobility Mass Spectrometry Uncovers the Impact of the Patterning of Oppositely Charged Residues on the Conformational Distributions of Intrinsically Disordered Proteins
- (2019) Rebecca Beveridge et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Single-molecule fluorescence studies of intrinsically disordered proteins and liquid phase separation
- (2019) Irem Nasir et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Intrinsic GTPase Activity of K-RAS Monitored by Native Mass Spectrometry
- (2019) Zahra Moghadamchargari et al. BIOCHEMISTRY
- Fast photochemical oxidation of proteins(FPOP): A powerful mass spectrometry based structural proteomics tool
- (2019) Danté T Johnson et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- SERF engages in a fuzzy complex that accelerates primary nucleation of amyloid proteins
- (2019) Ben A. Meinen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins
- (2018) Jie Wang et al. CELL
- Unique insights to intrinsically disordered proteins provided by ion mobility mass spectrometry
- (2018) Dale Stuchfield et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing
- (2018) Ailin Wang et al. EMBO JOURNAL
- A User’s Guide for Phase Separation Assays with Purified Proteins
- (2018) Simon Alberti et al. JOURNAL OF MOLECULAR BIOLOGY
- Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
- (2018) Elizabeth L. Guenther et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Atomic structures of TDP-43 LCD segments and insights into reversible or pathogenic aggregation
- (2018) Elizabeth L. Guenther et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Analysis of the oligomeric states of nucleophosmin using size exclusion chromatography
- (2018) Gyosuke Sakashita et al. Scientific Reports
- NFGAIL Amyloid Oligomers: The Onset of Beta-Sheet Formation and the Mechanism for Fibril Formation
- (2017) Waldemar Hoffmann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Addressing a Common Misconception: Ammonium Acetate as Neutral pH “Buffer” for Native Electrospray Mass Spectrometry
- (2017) Lars Konermann JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
- High-fidelity mass analysis unveils heterogeneity in intact ribosomal particles
- (2017) Michiel van de Waterbeemd et al. NATURE METHODS
- Biomolecular condensates: organizers of cellular biochemistry
- (2017) Salman F. Banani et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation
- (2017) Tariq Afroz et al. Nature Communications
- The Structure and Dynamics of Higher-Order Assemblies: Amyloids, Signalosomes, and Granules
- (2016) Hao Wu et al. CELL
- Phase separation in biology; functional organization of a higher order
- (2016) Diana M. Mitrea et al. Cell Communication and Signaling
- The diverse and expanding role of mass spectrometry in structural and molecular biology
- (2016) Philip Lössl et al. EMBO JOURNAL
- ALS Mutations Disrupt Phase Separation Mediated by α-Helical Structure in the TDP-43 Low-Complexity C-Terminal Domain
- (2016) Alexander E. Conicella et al. STRUCTURE
- Structure of the ribosome post-recycling complex probed by chemical cross-linking and mass spectrometry
- (2016) Kristin Kiosze-Becker et al. Nature Communications
- Nucleophosmin integrates within the nucleolus via multi-modal interactions with proteins displaying R-rich linear motifs and rRNA
- (2016) Diana M Mitrea et al. eLife
- Mass Determination of Entire Amyloid Fibrils by Using Mass Spectrometry
- (2015) Tristan Doussineau et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Chemical cross-linking and native mass spectrometry: A fruitful combination for structural biology
- (2015) Andrea Sinz et al. PROTEIN SCIENCE
- Relating gas phase to solution conformations: Lessons from disordered proteins
- (2015) Rebecca Beveridge et al. PROTEOMICS
- Collision Cross Sections for Structural Proteomics
- (2015) Erik G. Marklund et al. STRUCTURE
- Screening and classifying small-molecule inhibitors of amyloid formation using ion mobility spectrometry–mass spectrometry
- (2014) Lydia M. Young et al. Nature Chemistry
- A mass spectrometry–based hybrid method for structural modeling of protein complexes
- (2014) Argyris Politis et al. NATURE METHODS
- Phase transitions in the assembly of multivalent signalling proteins
- (2012) Pilong Li et al. NATURE
- Aβ40 and Aβ42 Amyloid Fibrils Exhibit Distinct Molecular Recycling Properties
- (2011) Laia Sánchez et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Structural organization of brain-derived mammalian prions examined by hydrogen-deuterium exchange
- (2011) Vytautas Smirnovas et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Active liquid-like behavior of nucleoli determines their size and shape in Xenopus laevis oocytes
- (2011) C. P. Brangwynne et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Polydispersity of αB-Crystallin Is Rationalized by an Interconverting Polyhedral Architecture
- (2011) Andrew J. Baldwin et al. STRUCTURE
- How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas phase
- (2010) Ewa Jurneczko et al. ANALYST
- Ion mobility–mass spectrometry reveals a conformational conversion from random assembly to β-sheet in amyloid fibril formation
- (2010) Christian Bleiholder et al. Nature Chemistry
- Germline P Granules Are Liquid Droplets That Localize by Controlled Dissolution/Condensation
- (2009) C. P. Brangwynne et al. SCIENCE
- Collisional activation of protein complexes: Picking up the pieces
- (2008) Justin L. P. Benesch JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now