Overexpression of PLK3 Mediates the Degradation of Abnormal Prion Proteins Dependent on Chaperone-Mediated Autophagy

Inhibition of Polo-like kinase 1 reduces beta-amyloid-induced neuronal cell death in Alzheimer's disease

(2016) Bing Song et al.   Aging-US

Polo-like kinase 3 (PLK3) mediates the clearance of the accumulated PrP mutants transiently expressed in cultured cells and pathogenic PrPSc in prion infected cell line via protein interaction

(2015) Hui Wang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

FBXW7-Induced MTOR Degradation Forces Autophagy to Counteract Persistent Prion Infection

(2015) Yin Xu et al.   MOLECULAR NEUROBIOLOGY

Regulated degradation of Chk1 by chaperone-mediated autophagy in response to DNA damage

(2015) Caroline Park et al.   Nature Communications

Activation of the AMPK-ULK1 pathway plays an important role in autophagy during prion infection

(2015) Xue-Yu Fan et al.   Scientific Reports

Sorting out the trash: the spatial nature of eukaryotic protein quality control

(2014) Emily M Sontag et al.   CURRENT OPINION IN CELL BIOLOGY

Overexpression of p62/SQSTM1 promotes the degradations of abnormally accumulated PrP mutants in cytoplasm and relieves the associated cytotoxicities via autophagy–lysosome-dependent way

(2013) Yin Xu et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Abortive Cell Cycle Events in the Brains of Scrapie-Infected Hamsters with Remarkable Decreases of PLK3/Cdc25C and Increases of PLK1/Cyclin B1

(2013) Hui Wang et al.   MOLECULAR NEUROBIOLOGY

Emerging regulation and functions of autophagy

(2013) Patricia Boya et al.   NATURE CELL BIOLOGY

Activation of the macroautophagic system in scrapie-infected experimental animals and human genetic prion diseases

(2012) Yin Xu et al.   Autophagy

Misfolded PrP and a novel mechanism of proteasome inhibition

(2012) Ralph Andre et al.   Prion

Heat shock protein 70 selectively mediates the degradation of cytosolic PrPs and restores the cytosolic PrP-induced cytotoxicity via a molecular interaction

(2012) Jin Zhang et al.   Virology Journal

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

From Plk1 to Plk5

(2011) Guillermo de Cárcer et al.   CELL CYCLE

Chaperone-mediated autophagy at a glance

(2011) S. Kaushik et al.   JOURNAL OF CELL SCIENCE

Familial CJD Associated PrP Mutants within Transmembrane Region Induced Ctm-PrP Retention in ER and Triggered Apoptosis by ER Stress in SH-SY5Y Cells

(2011) Xin Wang et al.   PLoS One

Prions

(2011) D. W. Colby et al.   Cold Spring Harbor Perspectives in Biology

Autophagy gone awry in neurodegenerative diseases

(2010) Esther Wong et al.   NATURE NEUROSCIENCE

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Constitutive Activation of Chaperone-mediated Autophagy in Cells with Impaired Macroautophagy

(2008) Susmita Kaushik et al.   MOLECULAR BIOLOGY OF THE CELL

Protein microarray analysis identifies human cellular prion protein interactors

(2008) J. Satoh et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY