From Plk1 to Plk5

Polo-like Kinase Plk2 Is an Epigenetic Determinant of Chemosensitivity and Clinical Outcomes in Ovarian Cancer

(2011) N. Syed et al.   CANCER RESEARCH

Plk2 regulated centriole duplication is dependent on its localization to the centrosome and a functional polo-box domain

(2011) Onur Cizmecioglu et al.   CELL CYCLE

Plk5, a Polo Box Domain-Only Protein with Specific Roles in Neuron Differentiation and Glioblastoma Suppression

(2011) G. de Carcer et al.   MOLECULAR AND CELLULAR BIOLOGY

A role for Drosophila Polo protein in chromosome resolution and segregation during mitosis

(2010) Susana Godinho et al.   CELL CYCLE

PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle

(2010) Jaerak Chang et al.   EMBO JOURNAL

Stepwise evolution of the centriole-assembly pathway

(2010) Z. Carvalho-Santos et al.   JOURNAL OF CELL SCIENCE

Plk2 attachment to NSF induces homeostatic removal of GluA2 during chronic overexcitation

(2010) Danielle M Evers et al.   NATURE NEUROSCIENCE

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

The novel mouse Polo-like kinase 5 responds to DNA damage and localizes in the nucleolus

(2010) Zdenek Andrysik et al.   NUCLEIC ACIDS RESEARCH

Plk4 is required for cytokinesis and maintenance of chromosomal stability

(2010) C. O. Rosario et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional Whole-genome Analysis Identifies Polo-like Kinase 2 and Poliovirus Receptor as Essential for Neuronal Differentiation Upstream of the Negative Regulator αB-crystallin

(2009) Cristina Draghetti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Plk1 Self-Organization and Priming Phosphorylation of HsCYK-4 at the Spindle Midzone Regulate the Onset of Division in Human Cells

(2009) Mark E. Burkard et al.   PLOS BIOLOGY

Polo-Like Kinase 1 Directs Assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF Complex to Initiate Cleavage Furrow Formation

(2009) Benjamin A. Wolfe et al.   PLOS BIOLOGY

Polo-like Kinase 3 Functions as a Tumor Suppressor and Is a Negative Regulator of Hypoxia-Inducible Factor-1  under Hypoxic Conditions

(2008) Y. Yang et al.   CANCER RESEARCH

Emerging cancer therapeutic opportunities by inhibiting mitotic kinases

(2008) Ignacio Pérez de Castro et al.   CURRENT OPINION IN PHARMACOLOGY

Sequestration of Polo kinase to microtubules by phosphopriming-independent binding to Map205 is relieved by phosphorylation at a CDK site in mitosis

(2008) V. Archambault et al.   GENES & DEVELOPMENT

Regulation of Postsynaptic RapGAP SPAR by Polo-like Kinase 2 and the SCFβ-TRCPUbiquitin Ligase in Hippocampal Neurons

(2008) Xiaolu L. Ang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Polo-like Kinase 3 by Hypoxic Stresses

(2008) Ling Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polo-like Kinase 2 (PLK2) Phosphorylates α-Synuclein at Serine 129 in Central Nervous System

(2008) Kelly J. Inglis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polo-Like Kinase 1 Is Essential for Early Embryonic Development and Tumor Suppression

(2008) L.-Y. Lu et al.   MOLECULAR AND CELLULAR BIOLOGY

Critical Role of CDK5 and Polo-like Kinase 2 in Homeostatic Synaptic Plasticity during Elevated Activity

(2008) Daniel P. Seeburg et al.   NEURON

Bora and the Kinase Aurora A Cooperatively Activate the Kinase Plk1 and Control Mitotic Entry

(2008) A. Seki et al.   SCIENCE