Early growth response factor 1 upregulates pro-fibrotic genes through activation of TGF-β1/Smad pathway via transcriptional regulation of PAR1 in high-glucose treated HK-2 cells
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Early growth response factor 1 upregulates pro-fibrotic genes through activation of TGF-β1/Smad pathway via transcriptional regulation of PAR1 in high-glucose treated HK-2 cells
Authors
Keywords
-
Journal
MOLECULAR AND CELLULAR ENDOCRINOLOGY
Volume 572, Issue -, Pages 111953
Publisher
Elsevier BV
Online
2023-05-11
DOI
10.1016/j.mce.2023.111953
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Hirudin improves renal interstitial fibrosis by reducing renal tubule injury and inflammation in unilateral ureteral obstruction (UUO) mice
- (2020) Yongxiang Xie et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Epigenetics and epigenomics in diabetic kidney disease and metabolic memory
- (2019) Mitsuo Kato et al. Nature Reviews Nephrology
- Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF‐α‐Smurf1‐Akt‐mTOR‐P70S6K pathway
- (2019) Jiajun Zhou et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Distinct features of bivalent direct thrombin inhibitors, hirudin and bivalirudin, revealed by clot waveform analysis and enzyme kinetics in coagulation assays
- (2019) Masatoshi Wakui et al. JOURNAL OF CLINICAL PATHOLOGY
- Signaling Crosstalk of TGF-β/ALK5 and PAR2/PAR1: A Complex Regulatory Network Controlling Fibrosis and Cancer
- (2018) Hendrik Ungefroren et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Early growth response protein 1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease
- (2018) Yan-Lin Yang et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Combined long-term caffeine intake and exercise inhibits the development of diabetic nephropathy in OLETF rats
- (2017) Masato Suzuki et al. JOURNAL OF APPLIED PHYSIOLOGY
- Egr-1 Mediates Chronic Hypoxia-Induced Renal Interstitial Fibrosis via the PKC/ERK Pathway
- (2017) Shiren Sun et al. AMERICAN JOURNAL OF NEPHROLOGY
- Trends in Prevalence of Chronic Kidney Disease in the United States
- (2016) Daniel Murphy et al. ANNALS OF INTERNAL MEDICINE
- TGF-β: the master regulator of fibrosis
- (2016) Xiao-ming Meng et al. Nature Reviews Nephrology
- Protease-activated receptor-1 deficiency protects against streptozotocin-induced diabetic nephropathy in mice
- (2016) Maaike Waasdorp et al. Scientific Reports
- Transcription Factor Egr1 is Involved in High Glucose-Induced Proliferation and Fibrosis in Rat Glomerular Mesangial Cells
- (2015) Dan Wang et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The emerging role of coagulation proteases in kidney disease
- (2015) Thati Madhusudhan et al. Nature Reviews Nephrology
- New developments concerning the proximal tubule in diabetic nephropathy:in vitromodels and mechanisms
- (2015) Jennifer Slyne et al. NEPHROLOGY DIALYSIS TRANSPLANTATION
- Cell-Surface Receptors Transactivation Mediated by G Protein-Coupled Receptors
- (2014) Fabio Cattaneo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of matrix metalloproteinase-2 by halofuginone is mediated by the Egr1 transcription factor
- (2012) Eyal Zcharia et al. ANTI-CANCER DRUGS
- Targeting proteinase-activated receptors: therapeutic potential and challenges
- (2012) Rithwik Ramachandran et al. NATURE REVIEWS DRUG DISCOVERY
- Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial
- (2011) Edmund J. Lewis et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy
- (2011) H. Wang et al. BLOOD
- Regulation of thrombin-induced plasminogen activator inhibitor-1 in 4T1 murine breast cancer cells
- (2011) Troy A. McEachron et al. BLOOD COAGULATION & FIBRINOLYSIS
- Glomerular and Tubular Damage Markers Are Elevated in Patients With Diabetes
- (2011) F. L. Nauta et al. DIABETES CARE
- Sulodexide Fails to Demonstrate Renoprotection in Overt Type 2 Diabetic Nephropathy
- (2011) D. K. Packham et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Early growth response transcription factors: Key mediators of fibrosis and novel targets for anti-fibrotic therapy
- (2011) Swati Bhattacharyya et al. MATRIX BIOLOGY
- Thrombin down-regulates the TGF-β-mediated synthesis of collagen and fibronectin by human proximal tubule epithelial cells through the EPCR-dependent activation of PAR-1
- (2010) Jong-Sup Bae et al. JOURNAL OF CELLULAR PHYSIOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started