Bortezomib attenuates renal interstitial fibrosis in kidney transplantation via regulating the EMT induced by TNF‐α‐Smurf1‐Akt‐mTOR‐P70S6K pathway

Bortezomib in Kidney Transplant: Current Use and Perspectives

(2018) Lucio R. Requiao-Moura et al.   CURRENT DRUG METABOLISM

ERK1/2-Dependent Gene Expression Contributing to TGFβ-Induced Lens EMT

(2018) Magdalena C. Wojciechowski et al.   CURRENT EYE RESEARCH

CKIP-1 affects the polyubiquitination of Nrf2 and Keap1 via mediating Smurf1 to resist HG-induced renal fibrosis in GMCs and diabetic mice kidneys

(2018) Wenyan Gong et al.   FREE RADICAL BIOLOGY AND MEDICINE

Role of tumor necrosis factor-α in epithelial-to-mesenchymal transition in transplanted kidney cells in recipients with chronic allograft dysfunction

(2018) Chunchun Zhao et al.   GENE

Smurf1 controls S phase progression and tumorigenesis through Wee1 degradation

(2017) Rongfei Wei et al.   FEBS LETTERS

Role of endothelial-to-mesenchymal transition induced by TGF-β1 in transplant kidney interstitial fibrosis

(2017) Zijie Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The proteasome inhibitor bortezomib attenuates renal fibrosis in mice via the suppression of TGF-β1

(2017) Moko Zeniya et al.   Scientific Reports

Angiotensin(1–7) attenuated Angiotensin II-induced hepatocyte EMT by inhibiting NOX-derived H 2 O 2 -activated NLRP3 inflammasome/IL-1β/Smad circuit

(2016) Li-Li Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

TGF-β: the connecting link between nephropathy and fibrosis

(2016) Brijesh Sutariya et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Proteomic Profiling of Radiation-Induced Skin Fibrosis in Rats: Targeting the Ubiquitin-Proteasome System

(2016) Wenjie Wang et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Cdh1 inhibits WWP2-mediated ubiquitination of PTEN to suppress tumorigenesis in an APC-independent manner

(2016) Jia Liu et al.   Cell Discovery

The Impact of Infection on Chronic Allograft Dysfunction and Allograft Survival After Solid Organ Transplantation

(2015) C. Martin-Gandul et al.   AMERICAN JOURNAL OF TRANSPLANTATION

SND1 Acts Downstream of TGF 1 and Upstream of Smurf1 to Promote Breast Cancer Metastasis

(2015) L. Yu et al.   CANCER RESEARCH

Advanced glycation end products accelerate arteriosclerosis after renal transplantation through the AGE/RAGE/ILK pathway

(2015) Xuzhong Liu et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Bortezomib prevents oncogenesis and bone metastasis of prostate cancer by inhibiting WWP1, Smurf1 and Smurf2

(2014) ZHIYU WANG et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Molecular mechanisms of epithelial–mesenchymal transition

(2014) Samy Lamouille et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Inhibitory Role of the KEAP1-NRF2 Pathway in TGFβ1-Stimulated Renal Epithelial Transition to Fibroblastic Cells: A Modulatory Effect on SMAD Signaling

(2014) In-geun Ryoo et al.   PLoS One

Bortezomib induces apoptosis of endometrial cancer cells through microRNA-17-5p by targeting p21

(2013) Yuan Shen et al.   CELL BIOLOGY INTERNATIONAL

Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat

(2010) R. Vogelbacher et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Rapamycin Inhibits PAI-1 Expression and Reduces Interstitial Fibrosis and Glomerulosclerosis in Chronic Allograft Nephropathy

(2009) Paola Pontrelli et al.   TRANSPLANTATION

In VivoInvestigations on Anti-Fibrotic Potential of Proteasome Inhibition in Lung and Skin Fibrosis

(2008) Serena Fineschi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY